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Associations of prenatal methylmercury exposure and maternal polyunsaturated fatty acid status with neurodevelopmental outcomes at 7 years of age : results from the Seychelles Child Development Study Nutrition Cohort 2
BACKGROUND: Fish is a primary source of protein and n-3 PUFA but also contains methylmercury (MeHg), a naturally occurring neurotoxicant to which, at sufficient exposure levels, the developing fetal brain is particularly sensitive. OBJECTIVES: To examine the association between prenatal MeHg and maternal status of n-3 and n-6 PUFA with neurodevelopment, and to determine whether PUFA might modify p
Replik: Svepande påståenden men inget nytt
Medical and nonmedical information during multidisciplinary team meetings in cancer care
Background: Multidisciplinary team (MDT) meetings provide treatment recommendations based on available information and collective decision-making in teams with complementary professions, disciplines and skills. We aimed to map ancillary medical and nonmedical patient information during case presentations and case discussions in MDT meetings in cancer care. Methods: Through a nonparticipant, observ
Influence of core divisome proteins on cell division in Streptomyces venezuelae ATCC 10712
The sporulating, filamentous soil bacterium Streptomyces venezuelae ATCC 10712 differentiates under submerged and surface growth conditions. In order to lay a solid foundation for the study of development-associated division for this organism, a congenic set of mutants was isolated, individually deleted for a gene encoding either a cytoplasmic (i.e. ftsZ) or core inner membrane (i.e. divIC, ftsL,
Exogenous LL-37 but not homogenates of desquamated oral epithelial cells shows activity against Streptococcus mutans
Objective: The antimicrobial peptide hCAP18/LL-37 is detected in desquamated epithelial cells of human whole saliva, but the functional importance of this pool of hCAP18/LL-37 is not understood. Here, we assess the impact of homogenates of desquamated oral epithelial cells and exogenous, synthetic LL-37 on two oral bacteria: S. mutans and S. gordonii. Material and methods: Desquamated epithelial c
A comparison of MyPKFiT and WAPPS-Hemo as dosing tools for optimizing prophylaxis in patients with severe haemophilia A treated with Octocog alfa
Introduction: MyPKFiT and the Web-Accessible Population Pharmacokinetic service—Hemophilia (WAPPS-Hemo) are web-based population-based applications developed for helping physicians individualize and optimize replacement therapy. Although MyPKFiT is intended for Octocog alfa and Rurioctocog alfa pegol use only, the WAPPS-Hemo is applicable to all factor VIII concentrates. Aim: To compare MyPKFiT an
Rekindling the Agenda on Women, Peace and Security: can the EU lead by example?
The terrain of war and peace is not gender neutral. This was recognised for the first time by the UN Security Council in its resolution 1325 (UNSC 1325) adopted on 31 October 2000. It is a historic decision for the global efforts to achieve the equality of women and girls in this terrain. For the first time, the principal organ with primary responsibility for international security acknowledged a
Restoring the rule of law within the EU. In judges we trust
Single-cell sequencing in translational cancer research and challenges to meet clinical diagnostic needs
The ability to capture alterations in the genome or transcriptome by next-generation sequencing has provided critical insight into molecular changes and programs underlying cancer biology. With the rapid technological development in single-cell sequencing, it has become possible to study individual cells at the transcriptional, genetic, epigenetic, and protein level. Using single-cell analysis, an
Management of Spontaneous Isolated Mesenteric Artery Dissection : A Systematic Review
Background and Aims: There are increasing reports on case series on spontaneous isolated mesenteric artery dissection, that is, dissections of the superior mesenteric artery and celiac artery, mainly due to improved diagnostic capacity of high-resolution computed tomography angiography performed around the clock. A few case–control studies are now available, while randomized controlled trials are
Recombinant FVIIa in elective non-orthopaedic surgery of adults with haemophilia and inhibitors : A systematic literature review
Aim: To assess available evidence on the use of rFVIIa in non-orthopaedic surgery including dental surgery in adult patients with congenital haemophilia with inhibitors (PWHI). Methods: A systematic literature search was performed according to a prespecified search string; prespecified criteria were used to select applicable studies including PWHI ≥18 years of age who underwent any non-orthopaedic
Asymmetric contributions of seed and pollen to gene dispersal in the marsh orchid Dactylorhiza umbrosa in Asia Minor
Orchids differ from other plants in their extremely small and partly air-filled seeds that can be transported long distances by wind. Seed dispersal in orchids is expected to contribute strongly to overall gene flow, and orchids generally express low levels of genetic differentiation between populations and low pollen to seed flow ratios. However, studies in orchids distributed in northern Europe
Short time to blood culture positivity in Enterococcus faecalis infective endocarditis
Time to blood culture positivity (TTP) is an indirect measure of bacterial concentration in blood. A short TTP has been linked to the presence of infective endocarditis (IE) and to poor prognosis in Staphylococcus aureus bacteremia. We analyze factors influencing TTP in bacteremia with Enterococcus faecalis. This retrospective observational study of medical records included adults diagnosed with m
Sibling correlation in risk attitudes : evidence from Burkina Faso
This study uses sibling correlation to provide novel descriptive evidence of parental and household characteristics on three different risk domains collected in a nationally representative survey from Burkina Faso. The sibling correlations are between 0.51 and 0.83. The correlations are higher in the general risk domain compared to risk taking in financial matters and traffic. Moreover, the siblin
Intergenerational transmission of risk attitudes in Burkina Faso
Previous research shows that transmission of attitudes in the family is gendered. However, there are limited findings about intergenerational transmission of risk attitudes and whether it is gendered. This study replicates the findings by Dohmen et al. (Rev Econ Stud 79(2):645–677) for Germany by using quantitative data from Burkina Faso in 2014 to analyze three different self-reported risk questi
Om ofrivillig ensamhet bland äldre : Intervjuer och dialog med yrkesverksamma inom Vård- och omsorgsförvaltningen i Helsingborg
År 2020 genomfördes ett deltagarbaserat projekt om ofrivillig ensamhet bland äldre inom Vård- och omsorgsförvaltningen i Helsingborg. Syftet med studien var att undersöka hur ett antal anställda inom olika verksamheter och på olika nivåer inom Vård- och omsorgsförvaltningen resonerade om ofrivillig ensamhet och analysera hur de förhållningssätt, strategier och strukturer som framträdde kunde först
Kanadamodellen – kollektivavtal i kampen mot sexuella trakasserier
Tio år med Diskrimineringsombudsmannen - En rapport om nedmontering av diskrimineringsskyddet
Street Artivism on Athenian Walls : A cognitive semiotic analysis of metaphor and narrative in street art
The thesis is a collection of four papers on Greek street art (specifically situated in the city of Athens) with a focus on metaphors and narratives. The overall aim guiding this thesis is to explore how street art in times of crisis can represent sociopolitical issues and in what ways these messages can be conveyed. By using the perspective of cognitive semiotics to address this, a parallel aim i