In the first years of the twentieth century, numerous attempts were made at powered flight. What is commonly labelled 'the pioneer era' (1900-1914) covers the unsteady beginnings of the motorized airplane as well as its large-scale introduction in warfare and for the transportation of goods and passengers. Initially regarded as a foolish toy for hazardous adventure, the airplane rapidly became a f

Aims and objectivesTo explore how nurses and managers perceive that evidence‐based sources are obtained to inform relevant nursing interventions.BackgroundImplementation of evidence‐based practice requires a systematic search and evaluation of research, clinical expertise and consideration of the patients’ preferences and values. Much has been written over the past decade about how this should be

Chaos in the debate: Common answer to the editor of META

Childhood and adolescence are critical periods for the skeleton. Mechanical load has then been shown to be one of the best stimuli to enhance not only bone mass, but also structural skeletal adaptations, as both contributing to bone strength. Exercise prescription also includes a window of opportunity to improve bone strength in the late pre- and early peri-pubertal period. There is some evidence

Multicolor imaging of vegetation fluorescence following laser excitation is reported for distances of 50 m. A mobile laser-radar system equipped with a Nd:YAG laser transmitter and a 40-cm-diameter telescope was utilized. The laser light was Raman shifted to 397 nm with pulse energies of approximately 30 mJ. An image-intensified CCD camera with a specially designed split-mirror Cassegrainian teles

It is generally considered mammals and birds have five Tec family kinases (TFKs): Btk, Bmx (also known as Etk), Itk, Tec, and Txk (also known as Rlk). Here, we discuss the domains and their functions and regulation in TFKs. Over the last few years, a large number of genomes from various phyla have been sequenced making it possible to study evolutionary relationships at the molecular and sequence l

The rostral migratory stream (RMS) is the main pathway by which newly born subventricular zone cells reach the olfactory bulb (OB) in rodents. However, the RMS in the adult human brain has been elusive. We demonstrate the presence of a human RMS, which is unexpectedly organized around a lateral ventricular extension reaching the OB, and illustrate the neuroblasts in it. The RMS ensheathing the lat

An arrangement for real-time fluorescence imaging of capillary electrophoretic separations is described. A decoated capillary was excited along a substantial part of its length by a dye laser pumped with an XeCl excimer laser tuned to match the fluorophors in the sample. Light emitted from the migrating, fluorescent molecules was detected by an image-intensified, thermoelectrically cooled charge-c

Foreign investors in the Nordic countries are most likely to find country risk arising from problems on the supply side, as in corporate structural changes. Such changes manifest themselves in a tendency toward concentration and internationalization on the macroeconomic level. Country risk can be divided into political risk and the risk of suspended payments, both of which are directly related to

A high-performance and flexible analog-to-digital converter (ADC), that can be integrated in deep-submicron CMOS technology, is a key building block for reduced size, cost and power consumption of digital communication systems. This dissertation concerns the investigation of particular problems associated with the design of such ADCs. The problem of increased clock jitter sensitivity of low-pass

The present study investigated whether the rotation rate induced by amphetamine in 6-OHDA-lesioned rats was predictive of development of l-DOPA-induced dyskinesia (LID) and success of the lesion procedure in our experimental settings. We collected data from 312 6-OHDA-lesioned rats (from different sets of experiments). Rats were subjected to the amphetamine-induced rotation test (2.5mg/kg) and chr

In this study, tactile sensitivity of gloved hand in the cold operation has been investigated. The relations among physical properties of protective gloves and hand tactile sensitivity and cold protection were also analysed both objectively and subjectively. Subjects with various gloves participated in the experimental study during cold exposure at different ambient temperatures of -12°C and -25°C