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This article describes the combination of self-assembled peptide nanofibrils with metal electrodes for the development of an electrochemical metal-ion biosensor. The biological nanofibrils were immobilized on gold electrodes and used as biorecognition elements for the complexation with copper ions. These nanofibrils were obtained under aqueous conditions, at room temperature and outside the clean

Results based on virtual instrument models for the first high-flux, high-resolution, spallation based, backscattering spectrometer, BASIS are presented in this paper. These were verified using the Monte Carlo instrument simulation packages McStas and VITESS. Excellent agreement of the neutron count rate at the sample position between the virtual instrument simulation and experiments was found, in

Previously, a lower risk of colorectal cancer was observed with fruit and vegetable consumption in the European Prospective Investigation into Cancer and Nutrition within a follow-up period of nine years which was not fully supported by a recent meta-analysis. Therefore, we were interested in the relation with extended follow-up, also focusing on single subtypes and variety of intake of fruit and

Terminal alkynyl and azide groups are introduced on the surface of molecularly imprinted core-shell nanoparticles using precipitation polymerization. These clickable groups enable simple nanoparticle conjugation and surface modification under mild reaction conditions, opening new opportunities for nanoparticle-based assays and chemical sensing.

In this article, it is pointed out that the European Union does not have a harmonized practice when it comes to trade procedures, implying that countries in the rest of the world face different trade barriers depending on which EU country they ship their goods to. Estimating the impact of trade procedures on exports from non-EU countries, a highly statistically significant and negative effect is f

There is an increasing recognition of the healthcare needs of long-term childhood and adolescent cancer survivors, but less information is known about the education and training needs of healthcare professionals.

To assess the age and origin of the metasedimentary migmatites in southernmost Sweden and their relationships with the Mesoproterozoic granitoid magmatism in the area, we have dated migmatite zircon using the secondary ion mass spectrometry U-Pb method. The studied metasedimentary migmatites, here called the Noteboda migmatites, occur along the southwestern boundary of the 1442 Ma Taghusa granitoi

The COX2 rs5277 (306G>C) polymorphism has been associated with inflammation-associated cancers. In breast cancer, tumor COX-2 expression has been associated with increased estrogen levels in estrogen receptor (ER)-positive and activated Akt-pathway in ER-negative tumors. Our study investigated the impact of COX2 genotypes on early breast cancer events and treatment response in relation to tumor ER

Streptococcus dysgalactiae subsp. equisimilis (SDSE) can cause recurrent bacteremic infection. We have characterized novel virulence properties of an SDSE isolate of type stG485.0 that caused severe sepsis three times in a patient despite that he had opsonizing antibodies to the isolate. An infected aortic aneurysm was suspected to be the focus for the persisting bacteria. For the first time we sh

Open source components can be used as one type of software component in development of commercial software. In development using this type of component, potential open source components must first be identified, then specific components must be selected, and after that selected components should maybe be adapted before they are included in the developed product. A company using open source compone

Objective. An association between 25-hydroxyvitamin D (25[ OH] D; vitamin D) deficiency and increased cardiovascular (CV) risk factors and CV disease (CVD) has been shown in general population studies. Vitamin D deficiency has been noted in systemic lupus erythematosus (SLE), and CVD is a major cause of morbidity and mortality in SLE. The objectives of this study were to estimate the associations

BACKGROUND Men and women with type 1 long QT syndrome (LQT1) exhibit time-dependent differences in the risk for cardiac events. OBJECTIVE We hypothesized that sex-specific risk for LQT1 is related to the location and function of the disease-causing mutation in the KCNQ1 gene. METHODS The risk for life-threatening cardiac events (comprising aborted cardiac arrest [ACA] or sudden cardiac death [SCD]

In 1994 a cerebral palsy (CP) register and healthcare programme was established in southern Sweden with the primary aim of preventing dislocation of the hip in these children. The results from the first ten years were published in 2005 and showed a decrease in the incidence of dislocation of the hip, from 8% in a historical control group of 103 children born between 1990 and 1991 to 0.5% in a grou

Distributions sensitive to the underlying event are studied in events containing one or more chargedparticle jets produced in pp collisions at root s = 7 TeV with the ATLAS detector at the Large Hadron Collider (LHC). These measurements reflect 800 mu b(-1) of data taken during 2010. Jets are reconstructed using the anti-k(t) algorithm with radius parameter R varying between 0.2 and 1.0. Distribut

This study investigated the impact of well geometry and surface reflectance on vertical daylight factors on the walls of rectangular atria under a CIE standard overcast sky. The vertical daylight factors predicted using the modelling software Radiance were validated by artificial sky scale model measurements. More simulated data of vertical daylight factors for a very wide range of rectangular atr

It is well known that in the context of the classical regression model with heteroskedastic errors, while ordinary least squares (OLS) is not efficient, the weighted least squares (WLS) and quasi-maximum likelihood (QML) estimators that utilize the information contained in the heteroskedasticity are. In the context of unit root testing with conditional heteroskedasticity, while intuition suggests

We have studied the production of neutral high-Rydberg (HR) fragments from the CH4 molecule at the C 1s -> 3p excitation and at the C 1s ionization threshold. Neutral fragments in HR states were ionized using a pulsed electric field and the resulting ions were mass-analyzed using an ion time-of-flight spectrometer. The atomic fragments C(HR) and H(HR) dominated the spectra, but molecular fragments

Objective: Cancer quality registers are attracting increasing attention as important, but still underutilized sources of clinical data. To optimize the use of registers in quality assurance and improvement, data have to be rapidly collected, collated and presented as actionable, at-a-glance information to the reporting departments. This article presents a dashboard performance report on select qua

tThe PID controller is by far the most common controller, and to ensure good behavior under all circumstances, a PID implementation must consider many practical aspects such as integrator windup,derivative kick, and bumpless parameter and mode changes. In this paper, an entirely new issue for the derivative part is introduced and has been named derivative backoff. It occurs when the process value