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BACKGROUND: Autistic people are more likely to report problematic alcohol and other substance use when compared to the general population. Evidence suggests that up to one in three autistic adults may have an alcohol or other substance use disorder (AUD/SUD), although the evidence base for behavioural addictions is less clear. Autistic people may use substances or engage in potentially addictive b

BACKGROUND: Restrictive measures (RM) are prevalent in services for people with intellectual disabilities. This study investigates managerial awareness of RM and the nature of organisational supports required to reduce their use.METHOD: A survey asked front-line managers and staff what (RM) were used, their purpose, impact and importance (10-item Likert scales) and what organisational changes were

BACKGROUND: The Pediatric Outcomes Data Collection Instrument (PODCI) is a validated quality-of-life questionnaire with 6 domains designed to provide a standardized method of measuring outcomes in pediatric musculoskeletal conditions. To our knowledge there are no reports on its use in children with multiple hereditary exostosis (MHE).QUESTIONS/PURPOSES: Most published studies on MHE patients have

Structural brain MRI has proven invaluable in understanding movement disorder pathophysiology. However, most work has focused on grey/white matter volumetric (macrostructural) and white matter microstructural effects, limiting understanding of frequently implicated grey matter microstructural differences. Using ultra-strong spherical tensor encoding diffusion-weighted MRI, a persistent MRI signal

A significant problem in diffusion MRI (dMRI) is the lack of understanding regarding which microstructural features account for the variability in the diffusion tensor imaging (DTI) parameters observed in meningioma tumors. A common assumption is that mean diffusivity (MD) and fractional anisotropy (FA) from DTI are inversely proportional to cell density and proportional to tissue anisotropy, resp

The choroid plexus (ChP) is part of the blood-cerebrospinal fluid barrier, regulating brain homeostasis and the brain's response to peripheral events. Its upregulation and enlargement are considered essential in psychosis. However, the timing of the ChP enlargement has not been established. This study introduces a novel magnetic resonance imaging-based segmentation method to examine ChP volumes in

Magnetic resonance imaging (MRI) is the primary method for noninvasive investigations of the human brain in health, disease, and development but yields data that are difficult to interpret whenever the millimeter-scale voxels contain multiple microscopic tissue environments with different chemical and structural properties. We propose a novel MRI framework to quantify the microscopic heterogeneity

American photographer Jerry N. Uelsmann (1934–2022) was a seminal figure in photo history. Uelsmann catalyzed the transfer from modernist to post-modern photography with his at the time controversial photo montages and double exposures. Decades before the birth of digital image editing programs like Photoshop, Uelsmann created photo montages by combining several negatives in the darkroom. He start

Transmission electron microscopy (TEM) is an atomic resolution technique that allows for in depth analysis of the properties of different materials by passing high energy electrons through a thin sample and detecting how they are affected. However, due to the strong interaction between electrons and matter, the probability of the sample remaining unperturbed by the electron irradiation is small. T

Although the effects of captive offshoring on firm innovation have increasingly become a subject of study, the literature did so far not distinguish between the effects on introducing innovation as opposed to the effects their market diffusion. This distinction is important. By integrating insights from the innovation diffusion literature, we argue that the effects of captive offshoring on home ba

Background: Intraventricular haemorrhage (IVH) is a major complication of preterm birth. Large haemorrhages are associated with a high risk of disability and hydrocephalus. Instability of blood pressure and cerebral blood in the newborn flow are postulated as causative factors. Another mechanism may involve reperfusion damage from oxygen free radicals. It has been suggested that phenobarbital stab

Background: Workers in the construction industry are highly exposed to vibration from handheld equipment, which can have negative effects on the nerves and blood vessels in the hands. Employers in this industry often fail to comply with legislation regarding vibration exposure. Aims: To assess carpenters' perceptions of proactive health and safety (H&S) management regarding hand-arm vibration

We first define a new multiplication on triangular Banach algebras. Then study amenability, weak amenability, biflatness and biprojectivity of these algebras.

This thesis consists of three self-contained papers studying different topics in health economics. The first chapter studies the substitution effect between in-person physician visits and a new type of doctor visits, direct-to-consumer (DCT) telemedicine, where a person can call a doctor directly via an app. To causally assess to which degree DCT consultations substitute for in-person consultation

Personalgruppens psykologi ger en grundläggande översikt över de psykologiska processer som kännetecknar en personalgrupp. Enkelt och lättillgängligt presenterar författarna teorier och begrepp som kan fungera som redskap för att förstå arbetslagets och samarbetets psykologiska villkor. Teori varvas med praktiska övningar och resonemang kring hur samarbetsproblem och konflikter kan förebyggas och