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An efficient approach was developed for ester-linking the sterically hindered carboxy group of N-acetylneuraminic acid with the secondary hydroxy group at C(2) of galactose. Putative precursors of the glycosidically linked disaccharide Neu5Ac-(2-3)-Gal were prepared.
Hematopoietic stem cells (HSCs) are primitive tissue-specific somatic stem cells, responsible for the maintenance and replenishment of the bone marrow (BM) and subsequently the entire blood system. The never-ending ability to differentiate into all the mature hematopoietic lineages makes these HSCs attractive candidates for use in future regenerative medicine. HSCs are balanced between different f
The two nuclei Cd-98 and Sn-102, closest neighbours of Sn-100, have been studied with a recoil catcher setup, following the reactions: Ni-58(Ti-46, alpha 2n)Cd-98 and Ni-58(Cr-50, alpha 2n)Sn-102. Long lived isomeric states were measured in Cd-98 I-pi = (8+), t(1/2) = 0.48(8) mu s and in Sn-102 I-pi = (6(+)) with t(1/2) = 1.0(6) mu s. The proposed experimental level schemes of the isomeric decay a
Boken är utgiven med anledning av Lars-Erik Nevanders 70-årsdag och baseras på ett symposium i Lund 1991 med föredrag av personer som arbetat med Nevander under hans tid som professor i Lund. Föredragen hölls av en bred samling internationella namn och omfattar ett brett spektrum bl a klimat & fuktfrågor, betong- och murverkskonstruktioner m.m.This book is dedicated to Lars Erik Nevander, who turned 70 in the autumn of 1991. An international symposium was held in Lund in September of 1991 to which participants were specially invited who had worked with Lars Erik Nevander in one connection or another during the time of his professorship at Lund University. Invited papers presented by some 20 of the participants illurninated important d
Electrochemical and fluorometric studies on a few selected phenazine and phenoxazine dyes has been carried out in free conditions and when covalently attached to a protein. The dyes have been coupled using the conventional coupling agent carbodiimide (derivative). Neutral Red and Nile Blue A, show significant shifts in their emission peaks to shorter wavelengths on binding to bovine serum albumin
Knowledge of effects of moisture exposure on timber structures is important for serviceability and load bearing capacity of timber elements and systems. Varying climate affects the moisture content profiles in timber as the relative humidity changes in the ambient air. This paper presents methods for calculation of diffusion based moisture transport and corresponding results on how timber responds
Pioneering work in the last century has resulted in a widely accepted paradigm that primary production is strongly positively related to temperature and water availability such that the northern hemispheric forest carbon sink may increase under conditions of global warming. However, the terrestrial carbon sink at the ecosystem level (i.e. net ecosystem productivity, NEP) depends on the net balance
Eight patients with colloid cysts of the third ventricle were examined with CT and MR. In six, surgical resection was performed and the material was subjected to histologic evaluation; the concentrations of trace elements were determined by particle-induced X-ray emission. Stereotaxic aspiration was performed in two. The investigation showed that colloid cysts are often iso- or hypodense relative
BMD and clinical risk factors predict hip and other osteoporotic fractures. The combination of clinical risk factors and BMD provide higher specificity and sensitivity than either alone. Introduction and hypotheses To develop a risk assessment tool based on clinical risk factors (CRFs) with and without BMD. Methods Nine population-based studies were studied in which BMD and CRFs were documented at
Defect reports are generated from various testing and development activities in software engineering. Some-times two reports are submitted that describe the same problem, leading to duplicate reports. These reports are mostly written in structured natural language, and as such, it is hard to compare two reports for similarity with formal methods. In order to identify duplicates, we investigate usi
Portal hypertension was induced in rats by partial ligation of the hepatic branches of the portal vein. After 5 days of hypertension the portal veins were taken out and mounted for isometric and quick-release experiments. Portal veins from sham-operated normal rats served as controls. The ligated veins had an increased cross-sectional area, indicating smooth-muscle hypertrophy. Although the absolu
The utility of the GHOST(3) cell assay has been evaluated for testing coreceptor use of primary human immunodeficiency virus type 1 (HIV-1) isolates. GHOST(3) cells were derived from the human osteosarcoma cell line, HOS, and have been engineered to stably express CD4 and one or another of the chemokine receptors CCR3, CCR5, CXCR4, Bonzo, or the orphan receptor BOB. The Indicator cell line carries
The fine-structure splittings of highly excited F-states in Cs were measured using high-resolution laser spectroscopy. The 12 and 132F states were found to be inverted with splittings ?E (122F)=-522(3) MHz and ?E (132F)=-416(3) MHz.
Anti-proliferative drugs have been used for immunosuppression since the introduction of clinical transplantation. Most transplant centres include azathioprine (Aza) and cyclosporine (CyA) in their standard regimens, despite several controlled studies having failed to confirm the benefit of this combination. Aza is still. the most commonly used anti-proliferative drug, although no major differences
