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Localization of cardiac arrhythmias : conventional noninvasive methods

Noninvasive localization of the accessory pathway (AP) in patients with the Wolff-Parkinson-White syndrome and of the site of origin of ventricular tachycardia (VT) is reviewed. 12-lead electrocardiography (ECG) is the most readily available method for localization of both the AP and the site of VT origin. Many published ECG criteria are introduced. The application of body surface potential mappin

Comparative study of eight sets of ECG criteria for the localization of the accessory pathway in Wolff-Parkinson-White syndrome

Eight sets of electrocardiographic (ECG) criteria for the localization of accessory conduction pathway (ACP) were evaluated on 182 patients with a single ACP. The Rosenbaum criteria identified 78.6% of the left-sided and 94.0% of the right-sided ACPs. Four of the other seven sets of criteria demonstrated a sensitivity higher than 70.9% and six showed a specificity higher than 74.9% in the 4-region

Comparative study of five preoperative methods for the localization of accessory pathways in the Wolff-Parkinson-White syndrome

One hundred and thirty-four cases of Wolff-Parkinson-White syndrome were studied to evaluate the relative usefulness of electrocardiography (ECG), electrophysiological studies (EPS), body surface mapping (BSM), gated blood-pool phase analysis (nuclear studies), and vectorcardiography (VCG) in the localization of the accessory pathway (ACP). In comparison with the final localization verified by int

Chemical and visual analysis of flint from Gotland and Öland

We have used visual and instrumental (EDXRF, energy-dispersive x-ray fluorescence) methods to analyse naturally occurring flint from Gotland and Öland. We compare the results with previously published analyses conducted on other types of flint. We identify two visually distinct types of flint from Gotland: grey flint and white/brown flint. The chemistry of the more common grey flint is unique comp

Nailed Steel Plate Connections : Strength and Ductile Failure Modes

This paper deals with theoretical and experimental investigations of nailed steel plate connections. For the experimental part, a total of 99 laboratory tests have been carried out in order to study failure mechanism and shear capacity of nailed steel plate connections. The testing programme comprised two nail lengths, two steel plate thicknesses and five nailing patterns. All tests related to loa

Effectiveness of HPV vaccination in women reaching screening age in Italy

Background and objectives A randomized trial was conducted in Tuscany, Italy, to evaluate the effectiveness of HPV vaccination for 25 year old (yo) women who attend at the first time cervical cancer screening. The trial also evaluated immune response after vaccination, reductions of cytological abnormalities and the impact of vaccination on screening activity. Study design During 2010–2011, all 25

Biomass or growth? How to measure soil food webs to understand structure and function

Food web links reflect the feeding rate of organisms and should thus capture the biomass production rate of the consumer. This information is rarely available for detrital food webs and has instead been inferred from biomass estimates to construct quantitative detrital food webs. Published method comparisons between biomass, growth and mineralisation show that microbial biomass is a poor predictor

Dose-volume analysis of radiation-induced trismus in head and neck cancer patients

Introduction: Trismus is a treatment-related late side effect in patients treated for cancer in the head and neck region (HNC). The condition can have a considerable negative impact on nutrition, dental hygiene, ability to speak and quality of life. We have previously studied trismus within the frame of a randomized phase 3 study of HNC patients treated with mainly three-dimensional (3D) conformal

Mismatch repair gene mutation spectrum in the Swedish Lynch syndrome population

Lynch syndrome caused by constitutional mismatch-repair defects is one of the most common hereditary cancer syndromes with a high risk for colorectal, endometrial, ovarian and urothelial cancer. Lynch syndrome is caused by mutations in the mismatch repair (MMR) genes i.e., MLH1, MSH2, MSH6 and PMS2. After 20 years of genetic counseling and genetic testing for Lynch syndrome, we have compiled the m

Chemical separation of disc components using RAVE

We present evidence from the RAdial Velocity Experiment (RAVE) survey of chemically separated, kinematically distinct disc components in the solar neighbourhood.We apply probabilistic chemical selection criteria to separate our sample into a-low ('thin disc') and a-high ('thick disc') sequences. Using newly derived distances,which will be utilized in the upcoming RAVE DR5, we explore the kinematic

Disentangling the visual cues used by a jumping spider to locate its microhabitat

Many arthropod species have evolved to thrive only on the leaves of a particular species of plant, which they must be capable of finding in order to survive accidental displacement, developmental transitions, or the changing of the seasons. A number of studies have tested whether such species select leaves to land or oviposit on based on their color, shape, or size. Unfortunately, many studies did

Using RGB displays to portray color realistic imagery to animal eyes

RGB displays effectively simulate millions of colors in the eyes of humans by modulating the relative amount of light emitted by 3 differently colored juxtaposed lights (red, green, and blue). The relationship between the ratio of red, green, and blue light and the perceptual experience of that light has been well defined by psychophysical experiments in humans, but is unknown in animals. The perc

The role of CART in islet function

Diminished insulin secretion and dysregulated glucagon secretion are key features of type 2 diabetes (T2D). The overall aim of this thesis was to study the role of cocaine- and amphetamine-regulated transcript (CART) in islet cell function and how CART regulates glucose homeostasis. We found that CART is expressed in human islet cells and that its expression is increased in patients with T2D, as w

Parity, breastfeeding and risk of coronary heart disease : A pan-European case-cohort study

Objective There is uncertainty about the direction and magnitude of the associations between parity, breastfeeding and the risk of coronary heart disease (CHD). We examined the separate and combined associations of parity and breastfeeding practices with the incidence of CHD later in life among women in a large, pan-European cohort study. Methods Data were used from European Prospective Investigat

A reference panel of 64,976 haplotypes for genotype imputation

We describe a reference panel of 64,976 human haplotypes at 39,235,157 SNPs constructed using whole-genome sequence data from 20 studies of predominantly European ancestry. Using this resource leads to accurate genotype imputation at minor allele frequencies as low as 0.1% and a large increase in the number of SNPs tested in association studies, and it can help to discover and refine causal loci.