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N-methyl-d-aspartate receptor autoimmunity affects cognitive performance in herpes simplex encephalitis

Objectives: To investigate the prevalence and temporal development of . N-methyl-d-aspartate receptor (NMDAR) autoantibodies in relation to neurocognitive performance in patients with herpes simplex encephalitis (HSE). Methods: This prospective observational study enrolled a total of 49 HSE patients within a randomized controlled trial of valacyclovir. Cerebrospinal fluid and serum samples were dr

A new algorithm for optimizing the wavelength coverage for spectroscopic studies : Spectral Wavelength Optimization Code (swoc)

The past decade and a half has seen the design and execution of several ground-based spectroscopic surveys, both Galactic and Extragalactic. Additionally, new surveys are being designed that extend the boundaries of current surveys. In this context, many important considerations must be done when designing a spectrograph for the future. Among these is the determination of the optimum wavelength co

Context, image and the case of the Shahbag movement

This research discusses the importance of a photograph of an accused war criminal, Abdul Kader Molla, during the period immediately before the emergence of the Shahbag movement in Bangladesh. The image captures Kader Molla flashing a V sign, and it was taken in the moments after he had been sentenced to life imprisonment by the International Crimes Tribunal in Bangladesh in 2013. After Kader Molla

Reduction of Streptococcus pneumoniae in upper respiratory tract cultures and a decreased incidence of related acute otitis media following introduction of childhood pneumococcal conjugate vaccines in a Swedish county

Background: The effect of pneumococcal conjugate vaccines (PCV) on invasive pneumococcal disease is frequently reported, but the impact on upper respiratory tract infections in a clinical setting is less documented. Our aim in this 5-year observational study was to investigate serotype changes in a large number of Streptococcus pneumoniae upper respiratory tract isolates following sequential intro

Antibodies against Phosphorylcholine among New Guineans Compared to Swedes : An Aspect of the Hygiene/Missing Old Friends Hypothesis

Background: We here study antibodies against phosphorylcholine (anti-PC) which we reported to be inversely associated with atherosclerosis, cardiovascular disease (CVD), and autoimmune conditions. In previous studies, we determined that this inverse association is more pronounced at low levels with high risk and at high levels, with decreased risk. We compare individuals from Kitava, New Guinea (w

Epidemiology of Familial Aggregation of Venous Thromboembolism

Familial aggregation (clustering) of venous thromboembolism (VTE) is the clustering of VTE within a family. Though several genes, such as antithrombin, protein C, protein S, factor V, and prothrombin are associated with the familial clustering of VTE, these loci only partially explain the familial aggregation of VTE. The epidemiology of the familial aggregation of VTE exhibits typical characterist

Sensitivity of VOF simulations of the liquid jet breakup to physical and numerical parameters

In this paper the characteristics of the primary breakup of a liquid jet is analyzed numerically. We applied the Volumes of Fluids (VOF) approach utilizing the Direction Averaged Curvature (DAC) model, to estimate the interface curvature, and the Direction Averaged Normal (DAN) model, to propagate the interface. While being used for the first time to predict liquid atomization, this methodology sh

Neighborhood socioeconomic characteristics and statin medication in patients with myocardial infarction : A Swedish nationwide follow-up study

Background: Coronary heart disease (CHD) and myocardial infarction (MI) are associated with neighborhood-level socioeconomic status (SES). Statins are important drugs for secondary prevention of MI. However, no study has determined whether neighborhood-level SES is associated with statin medication in MI patients. We aimed to determine whether there is a difference in statin medication rate in MI

Galectin-3 causes enteric neuronal loss in mice after left sided permanent middle cerebral artery occlusion, a model of stroke

In addition to brain injury stroke patients often suffer gastrointestinal complications. Neuroimmune interactions involving galectin-3, released from microglia in the brain, mediates the post-stroke pro-inflammatory response. We investigated possible consequences of stroke on the enteric nervous system and the involvement of galectin-3. We show that permanent middle cerebral artery occlusion (pMCA

Importance of carbon as limiting nutrient for bacterioplankton in a boreal sub-arctic coastal system.

Much debate has revolved around nutrient limitation in estuaries. A common view today is that nitrogen (N) and phosphorus (P) act as co-limiting nutrients, both for processes carried out by phytoplankton and by bacterioplankton, although recent studies show that also carbon (C) may control estuarine bacterioplankton, even in systems with large inputs of terrestrial organic matter (tOM). We conduct

Trading health for money: agential struggles in the (re)configuartion of subjectivity, the body and pain among construction workers

Construction work is physically demanding and often associated with bodily pain. This article presents a study of construction workers’ practices of using and relating to their bodies at work through an agential realist framework for analysing the (re)configuration of the workers’ embodied subjectivity. The analysis draws on interviews with 32 Danish construction workers as well as brief observati

Artificial Intelligence and the City : urbanistic Perspectives on AI

This book explores in theory and practice how artificial intelligence (AI) intersects with and alters the city. Drawing upon a range of urban disciplines and case studies, the chapters reveal the multitude of repercussions that AI is having on urban society, urban infrastructure, urban governance, urban planning and urban sustainability.Contributors also examine how the city, far from being a pass

Models for Non-Modelers : Understanding the Use of Models for Social Scientists and Others

Models for Non-Modelers focuses not on how to design models but on how to understand and critically appraise them. Data and statistical models are widely used in disciplines such as epidemiology, climate science and systems design, but it can be difficult for those without the necessary training to understand and implement them. This book is for non-modelers, especially social scientists. Through

Provsamlingen Swecrit och AI ger ny kunskap vid intensivvård

The unique Swecrit Biobank and its associated clinical registries for sepsis, ARDS, cardiac arrest, trauma, and COVID-19 include more than 150,000 blood samples and descriptions of critically ill patients. These assets provide a unique opportunity to research and improve the care of the most seriously ill patients through biomarker analyses, proteomic studies, and genetic and epigenetic studies us

A TDLAS-based photofragmentation method for spatially resolved measurement of KOH and KCl as well as its application in biomass combustion processes

The release of gas-phase potassium species, mainly KOH, KCl, and K atoms, from burning biomass fuels can introduce severe problems to boilers, such as fouling, slagging, and corrosion. In the present work, an optical technique combining laser-induced photofragmentation and tunable diode laser absorption spectroscopy is developed for simultaneously measuring the concentration of KOH, KCl and K atom