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Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO

Plasmodium falciparum is the causative agent of the most severe type of malaria, a life-threatening disease affecting the lives of over three billion people. Factors like widespread resistance against available drugs and absence of an effective vaccine are seriously compounding control of the malaria parasite. Thus, there is an urgent need for the identification and validation of new drug targets.

Individual variation and repeatability of sex pheromone emission of female turnip moths Agrotis segetum

Individual variation of the female sex pheromone signal in Agrotis segetum was determined by gas chromatographic analysis. The individuals varied extensively, both in absolute and relative amounts of the three major pheromone components; Z5-10:OAc, Z7-12:OAc and Z9-14:OAc. Within individuals there was a strong correspondence between the sex pheromone gland content and the signal actually emitted.

Interpretation of EXAFS spectra for sitting-atop complexes with the help of computational methods

The metallation of tetrapyrroles is believed to proceed via a sitting-atop (SAT) complex, in which some of the pyrrole nitrogen atoms are protonated and the metal ion resides above the ring plane. No crystal structure of such a complex has been presented, but NMR and EXAFS (extended X-ray absorption fine structure) data has been reported for Cu2+ in acetonitrile, which have been interpreted as the

Soil carbon sequestration in traditional farming in Sudanese dry lands

Do altered land management practices offer possibilities to sequester carbon in the soil and thereby mitigate increasing atmospheric CO2 as well as improve local soil fertility? This study investigates the impact of fallow periods on soil organic carbon in semiarid subsistence agroecosystems on sandy and poor soils in Kordofan, Sudan. The area is characterized by low-input cultivation of millet an

Meaning Constitution Analysis: A Phenomenological Approach

Each and every thought, word, feeling or action of a person recele a surplus of meaning, opening on all the possible worlds accessible for him/her. A vision on those possible worlds and possibilities of action, should be of the highest interest for psychological research. Research in cross/cultural/intercultural psychology confronts the researcher to language, in conversations, narratives, writing

The African Food Crisis: Lessons from the Asian Green Revolution.

This book is the outcome of a three-year project coordinated by a group of Swedish researchers and with collaborating scholars from Africa and Asia. It provides a comparative study between Asian agricultural development during the Green Revolution in food production and the current problematic agricultural situation in sub-Saharan Africa. Case studies of eight African and eight Asian countries (fo

Multi-Party Based Development and Decisions for a Nation-Wide Packaging Pool System

Planning and implementing an open-loop, business-wide national pool system for transport packaging (trays and pallets) is a complex process. This research project is focusing on the driving forces in the development and decision processes. During 1992-1999, a group of logistics specialists within the Swedish food supply chains took part in a development process, which included much learning and ne

Retirement – a new beginning or the beginning of the end?

The chapter explores what retirement means to women about to, or having recently retired in the current economic climate. It examines the choices perceived available to pre-retirement and retired people and their attitudes towards retirement. From our findings we are able to deduce that not everyone approaches retirement in the same way. Davies and Jenkins (2013) categorize individual-level experi

Health and disease in early Lund, Osteo-pathologic studies of 3,305 individuals buried in the cemetery area of Lund 990-1536

The purpose of this thesis is to characterize the health status of the population in early Lund. This is pursued by an osteological analysis of 3.305 individuals fron three time periods: c. 990-1100, c. 1100-1300 and c. 1300-1536. The individuals derives from cemeteries connected to four neighbouring churches, where one is the sucessor of the other (Trinitatis). One cemetery (Kattesund) is by and

U-model Based Adaptive IMC for Nonlinear Dynamic Plants.

A novel technique, involving U-model based IMC (Internal Model Control), is proposed for the adaptive control of nonlinear dynamic plants. The proposed scheme combines the robustness of the IMC and the ability of Neural Networks to identify arbitrary nonlinear functions, with the control-oriented nature of the U-model to achieve adaptive tracking of stable nonlinear plants. The proposed structure