Metastatic cancer spread is responsible for most cancer-related deaths. To colonize a new organ, invading cells adapt to, and remodel, the local extracellular matrix (ECM), a network of proteins and proteoglycans underpinning all tissues, and a critical regulator of homeostasis and disease. However, there is a major lack in tools to study cancer cell behavior within native 3D ECM. Here, an in-hous

The aim of this randomized controlled trial was to investigate the effects of guided internet-based cognitive be-havior therapy (ICBT) for posttraumatic stress disorder (PTSD). Sixty-two participants with chronic PTSD, asassessed by the Clinician-administered PTSD Scale, were recruited via nationwide advertising and randomizedto either treatment (n= 31) or delayed treatment attention control (n= 3

Objectives: To evaluate the effects of center experience and a variety of patient- and procedure-related factors on patient radiation exposure during prostatic artery embolization (PAE) in three Scandinavian centers with different PAE protocols and levels of experience. Understanding factors that influence radiation exposure is crucial in effective patient selection and procedural planning. Method

Mitochondrial dysfunction has been implicated in major depressive disorder (MDD). A measure of mitochondrial respiratory chain (RC) enzymatic activity—the Mitochondrial Health Index (MHI)—has previously been found to correlate with stress and emotional states in caregivers. We here report mitochondrial RC activities, mitochondrial DNA copy number (mtDNAcn), and the composite MHI in unmedicated and

Introduction A second peak of inhibitors has been reported in patients with severe hemophilia A (HA) aged >50 years in the United Kingdom. The reason for this suggested breakdown of tolerance in the aging population is unclear, as is the potential impact of regular exposure to the deficient factor by prophylaxis at higher age. No data on hemophilia B (HB) have ever been reported. Aim The ADVANCE W

Background and aims: Clinical support systems are widely used in pediatric care. The aim of this study was to assess the support for drug treatments used at pediatric cardiac wards and intensive care units in Sweden. Methods: Drug information, such as type of drug, indication, dose, and route of administration, for all in-hospital pediatric cardiac patients, was included in the study. Treatments w

Epithelial–mesenchymal transition (EMT) is a cellular process during which epithelial cells acquire mesenchymal phenotypes. Cancer cells undergo EMT to acquire malignant features and TGF-β is a key regulator of EMT. Here, we demonstrate for the first time that TGF-β could elicit EMT in a mouse lung adenocarcinoma cell line. TGF-β signaling activation led to cell morphological changes corresponding

Remiss över EU-kommissionens meddelande - Mot en modernare och mer europeisk ram för upphovsrätten - JURFAK 2016/3

In a world where copyright is being infringed in a plethora of ways, consumers find it difficult to access legal digital content. Therefore, this thesis investigates how copyright law governs access to legal content in the digital environment in respect of so-called consumptive use. By apprehending a user-centric approach I evaluate whether and how copyright law accounts for the consumer interest

Report on online copyright infringement and enforcement of rights in Sweden. Includes a description of applicable law and current practices. Part of Annex 2 in Quintais, J.P. Global Online Piracy Study: Legal Background Report, Institute of Information Law, University of Amsterdam, 2018 .

Critical opinion piece on the European parody exception in Article 5(3)(k) InfoSoc Directive, Article 17 DSM Directive, and parodies under Swedish copyright law. Published by Nordiskt Immateriellt Rättsskydd (NIR).

From a strict technological perspective copyright holders can today truly enforce their rights ex ante by creating closed environments in which the consumption of digital works is strictly controlled by DRM systems. The scope of such control is however usually attributable to a given business model rather than legal compliance because the copyright framework (and particularly Art. 6 InfoSoc Direct

Survey on national public sources of copyright flexibilities in Sweden, focusing on copyright exceptions and limitations, public domain, user rights and public interest. Part of ReCreating Europe project WP2 - End Users.

Survey on legal status of information society service providers in the pre- and post-CDSM Directive era in Sweden, focusing on service providers as intermediaries and as users of copyright-protected content (January 2021). Phase 1 report, part of ReCreating Europe project WP6 - Intermediaries.

The objective of the report is to review the state of the law and current legal responses to developments in AI and robotics and determine how specific questions/issues are addressed in Sweden. It highlights key legal developments pertaining to AI and robotics covering the last five to ten years; i.e. developments in AI that might have led to amendments in constitutional or human rights and/or leg

Internet är uppbyggt av länkar, vilket är centralt för dess funktion. Samtidigt länkas det i stor omfattning till både olovligt och lovligt upplagt upphovsrättsligt skyddat material. I upphovsrätten är det däremot inte klart när länkning till ett verk kan vara ett upphovsrättsintrång. EU-domstolen kommer dock under 2014 att avgöra tre länkningsmål.

In today’s knowledge-based global economy, most inventions are made by employed persons through their employers’ research and development activities. However, methods of establishing rights over an employee’s intellectual property assets are relatively uncertain in the absence of international solutions. Given that increasingly more businesses establish entities in different countries and more emp

Employees’ Intellectual Property Rights describes and analyses employers’ acquisition of employees’ intellectual property rights in thirty-four different jurisdictions worldwide collectively representing all habitable continents. In today’s knowledge-based global economy, most inventions are made by employed persons through their employers’ research and development activities. However, methods of