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Transverse and longitudinal Bose-Einstein correlations

We show how a difference in the correlation length longitudinally and transversely, with respect to the jet axis in e+e− annihilation, arises naturally in a model for Bose-Einstein correlations based on the Lund string model. In genuine three-particle correlations the difference is even more apparent and they provide therefore a good probe for the longitudinal stretching of the string field. The c

Beta-Cell-Targeted Expression of a Dominant-Negative Mutant of Hepatocyte Nuclear Factor-1{alpha} in Mice: Diabetes Model with {beta}-Cell Dysfunction Partially Rescued by Nonglucose Secretagogues.

We studied islet function in mice with beta-cell-targeted expression of a dominant-negative mutant of hepatocyte nuclear factor (HNF)-1alpha. At age 2-3 months, anesthetized transgenic and wild-type male mice underwent an intravenous glucose (1 g/kg) tolerance test (IVGTT). It was found that transgenic mice had an abolished insulin response in association with severe glucose intolerance. In other

Isolation, characterization, and enzymatic hydrolysis of acetyl-galactoglucomannan from spruce (Picea abies)

Water-soluble hemicelluloses were extracted from spruce chips by heat-fractionation using microwave treatment. A screening of conditions (pH, temperature and residence time) was performed for the extraction of O-acetyl-galactoglucomannan (AcGGM). The yield and the average molecular weight of the extracted mannan were analysed using HPLC, size-exclusion chromatography (SEC) and mass-spectrometry. T

Selection of Resistant Streptococcus pneumoniae during Penicillin Treatment In Vitro and in Three Animal Models.

Pharmacokinetic (PK) and pharmacodynamic (PD) properties for the selection of resistant pneumococci were studied by using three strains of the same serotype (6B) for mixed-culture infection in time-kill experiments in vitro and in three different animal models, the mouse peritonitis, the mouse thigh, and the rabbit tissue cage models. Treatment regimens with penicillin were designed to give a wide

Dynamic simulation of the steam supply system for a multi-cylinder dryer

A dynamic model and simulation program describing the principles of a steam supply system for a paper dryer were developed. The dynamics of a cylinder and the paper sheet during an altered valve position were studied. The results showed that the dynamic course during a pressure increase is different from the course during a pressure decrease. A potential method for the determination of the heat tr

A novel approach to monoclonal antibody separation using high performance liquid affinity chromatography (HPLAC) with SelectiSpher-10 protein G

Protein G, a bacterial cell wall protein extracted from strains of Streptococci, has been employed as a ligand in high performance liquid affinity chromatography (HPLAC) for separation of monoclonal antibodies. Examples are given of rapid high-resolution separations of rat and mouse monoclonal antibodies belonging to various subclasses. In comparison with protein A chromatography, we were able to

Genetic basis of the K phenotype in the Swedish population.

Abstract in Undetermined BACKGROUND: The absence of all Kell blood group antigens (K0 phenotype) is very rare. K0 persons, however, can produce clinically significant anti-Ku (K5) after transfusion and/or pregnancy and require K0 blood for transfusion. Ten alleles giving rise to the K0 phenotype have been reported: different populations were studied although none from Scandinavia. STUDY DESIGN AND

Variation in the content of glucosinolates, hydroxycinnamic acids, carotenoids, total antioxidant capacity and low-molecular-weight carbohydrates in Brassica vegetables

Bioactive compounds were investigated in genotypes (cauliflower 10, white cabbage 10, curly kale 1) and plant parts of the three crops. The content of most of the major glucosinolates glucobrassicin, sinigrin and glucoiberin differed significantly between cultivars. Samples harvested in 2000 had higher amounts of several glucosinolates than samples from 1999. Within cauliflower the buds of the flo

Development of Dual-broadband Rotational CARS for Combustion Diagnostics

The present thesis concerns development and application of dual-broadband rotational coherent anti-Stokes Raman spectroscopy (DB-RCARS) for temperature and species concentration measurements in combustion processes. Both fundamental development of the technique, including experimental as well as modelling results, and measurements in practical combustion devices were conducted. A code for calcula

How accurate is the CASPT2 method?

This paper is a reply to a recent paper on the isomers of trisulfur oxides (Chem. Commun., 2005, 3712) where the accuracy of the CASPT2 method is called in question. We illustrate that their results are due to an inadequate choice of active orbitals. Some results for related O and S containing molecules are also presented to strengthen the argumentation. It is concluded that the CASPT2 method is a

Improvement of spatial and temporal coherence of a broad area laser diode using an external-cavity design with double grating feedback

We demonstrate a novel technique for narrow bandwidth and highly improved lateral mode operation of a high-power broad area laser diode. The system uses simultaneous feedback from the first diffracted order and the zeroth reflected order of a diffraction grating. The two feedback paths lead to simultaneously improvement of the spectral and spatial properties of the laser diode. The laser system op

The Jurassic-Cretaceous transition of Southern Sweden - palynological and sedimentological interpretation

Palynological studies on the Vitaback Clay help resolve the position of the Jurassic-Cretaceous boundary in southern Sweden. Well-preserved assemblages of terrestrial pollen and spores, together with abundant algae (Botrycoccus), and for the first time, dinoflagellates have been identified in the Vitaback Clay. A Berriasian age is corroborated for the Vitaback Clay based on the palynological data;

Restrained point-charge models for disaccharides

Various methods for deriving atomic partial charges from the quantum chemical electrostatic potential and moments have been tested for the sucrose molecule. We show that if no further information is used, the charges on some carbon atoms become large and charge patterns involving these atoms are badly determined and poorly transferable. Adding lone-pairs on the ether oxygen atoms or dividing the m

Protein pre-fractionation in detergent-polymer aqueous two-phase systems for facilitated proteomic studies of membrane proteins

Pre-fractionation of a complex mixture of proteins increases the resolution in analytical separations of proteins from cells, tissues or organisms. Here we demonstrate a novel method for pre-fractionation of membrane proteins by a detergent-based aqueous two-phase system. Membrane proteins are strongly under-represented in proteomic studies based on two-dimensional electrophoresis (2-DE). As a mod

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A published investigation in 1961 of the vegetation on 10 burial mounds in southern Zealand was repeated in 2000. The burial mounds were situated as islands in the intensively used arable landscape. It is likely that such small fragments receive great inputs of Nitrogen by wet deposition and spill-over of artificial fertiliser from the surrounding fields. It was hypothesised that burial mounds in

A new approach to examine conformational changes occurring upon binding of ligand by biomolecules

Liquid-liquid partition chromatography in an aqueous poly(ethylene glycol)/dextran two-phase system (LLPC) is shown to be a quick and sensitive method for detecting conformational changes occurring upon binding of ligands by biospecific molecules. Two groups of well-characterized proteins, enzymes and monoclonal antibodies, were employed. As an example, LLPC demonstrated that isoforms of lactate d