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Popular Abstract in Swedish Den huvudsakliga hämmande signalsubstansen i hjärnan är GABA (gamma-aminobutyric acid, gamma-aminosmörsyra). GABA finns i ungefär hälften av alla nervceller i hjärnan och alla nervceller i hjärnan antas ha receptorer som binder GABA. Om man tänker på alla de normala neurologiska funktioner samt rubbningar där GABA är involverat är det inte svårt att förstå GABA:s oerhörInhibitory neurotransmission in the brain is mostly mediated by gamma-aminobutyric acid type A (GABAA) receptors. These receptors are involved in both phasic inhibition (point-to-point inhibition, synaptic transmission) and tonic inhibition (diffuse form of inhibition, brain homeostasis). In this thesis the functional and pharmacological properties of GABAA receptors expressed in brain slices or i

Three sesquiterpenoids that are found in the edible mushrooms Lactarius deliciosus, L. deterrimus and L. sanguifluus, have been assayed for biological activity. The compounds tested were a stearic acid ester of a sesquiterpene (I) and a sesquiterpene aldehyde (lactaroviolin, II) and alcohol (deterrol, III). The assays used were for mutagenic activity in the Ames Salmonella assay, for antimicrobial

Both theoretical and experimental studies of pleural fluid dynamics and lung buoyancy during steady-state, apneic conditions are presented. The theory shows that steady-state, top-to-bottom pleural-liquid flow creates a pressure distribution that opposes lung buoyancy. These two forces may balance, permitting dynamic lung floating, but when they do not, pleural-pleural contact is required. The ani

Aqueous di persions of a porcine lung surfactant (PLS) extract with and without cholesterol supplementation were analyzed by X-ray scattering. Lamellar liquid-crystalline and gel-type bilayer phases are formed, as in pure phosphatidylcholine (PC)-cholesterol systems. This PLS extract, developed for clinical applications, has a cholesterol content of less than 1% (w/w). Above the limit of swelling,

For a class of non-selfadjoint h-pseudodifferential operators in dimension 2, we determine all eigenvalues in an h-independent domain in the complex plane and show that they are given by a Bohr-Sommerfeld quantization condition. No complete integrability is assumed, and as a geometrical step in our proof, we get a KAM-type theorem (without small divisors) in the complex domain.

Popular Abstract in Swedish Denna avhandling presenterar en metod som kan hantera generella tjocka frekvensselektiva strukturer (FSS). Metoden är baserad på modanpassning och finita elementmetoden (FEM). Avhandlingen är en sammanläggningsavhandling och består av en introduktion som följs av fem vetenskapliga artiklar. Frekvensselektiva strukturer fungerar som filter för elektromagnetiska vågor, sThis thesis presents a new method that can handle a general thick Frequency Selective Structure (FSS), that consists of an arbitrary number of aperture layers and dielectric layers. The method is based on the Mode Matching Technique (MMT) and the finite element method (FEM). The thesis consists of a General Introduction and five scientific papers. The General Introduction gives an overview of fil

Summary In 1895 a posthumous essay by the Swedish poet and scholar Viktor Rydberg (1828- 1895) was published with the, for many modern Europeans, provoking title Den hvita rasens framtid (“The future of the white race”). In the late 20th century however “the white race” was a commonly used expression, it did not indicate any right-wing sympathies. Rydberg himself was a leftist, a social liberal. C

The study builds on a previous study of the everyday occupations of 100 women who worked at home and in the paid workforce. Their pattern of daily occupations was depicted using time-occupation graphs inspired by the time geography method, whereby the women’s pattern of occupations were categorised and clustered according to complexity. For each woman, the level of complexity was operationalised a

In this paper, we propose a new dynamic and efficient bounding volume hierarchy for breakable objects undergoing structured and/or unstructured motion. Our object-space method is based on different ways to incrementally update the hierarchy during simulation by exploiting temporal coherence and lazy evaluation techniques. This leads to significant advantages in terms of execution speed. Furthermor

Two biofilm reactors, using pumice stone and Poraver as biofilm supports, were run, based on the optimization of sulphide production using a factorial design. The maximum H2S concentrations reached were 10 and 15 mm, respectively, both being appropriate for metal precipitation in effluents. The set-up of the pumice stone biofilm reactor is suitable for application in the mining area in the Bolivia

The purpose of this long-term treatment study was to evaluate health-related quality of life by comparing the effects of diltiazem and atenolol on some important metabolic parameters. SUBJECTS, MATERIAL AND METHODS: In a Swedish-Finnish long-term multicenter study 256 patients with mild to moderate hypertension were randomized to treatment with diltiazem retard (D) (n = 127) or atenolol (A) (n = 1

Previous experimental studies have shown positive effects of hyperbaric oxygen treatment in the early regeneration phase in the first few days following a nerve injury. In this study, functional effects of hyperbaric oxygen treatment were studied in 2 series of rats after an injury to the sciatic nerve - a standardized crush injury and nerve transection and repair, respectively. Postoperatively th

Lead is one of the poisonous elements for de-NOx catalysts especially in the case of municipal waste incineration plants. Samples of a commercial selective catalytic reduction catalyst were impregnated with different amounts of Pb(NO3)(2), and their catalytic activities were studied. The XPS and SEM analysis showed higher lead concentration on the outer surface of the monolith than on the inside o

The regulation of a K+ current activating during oscillatory electrical activity (I-K,I-slow) in an insulin-releasing,beta-cell was studied by applying the perforated patch whole-cell technique to intact mouse pancreatic islets. The resting whole-cell conductance in the presence of 10 mm glucose amounted to 1.3 nS, which rose by 50% during a series of 26 simulated action potentials. Application of