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Clinical and genetical studies in cystic fibrosis and pseudohypoaldosteronism

Popular Abstract in Swedish Cystisk fibros (CF) är den vanligaste svåra ärftliga metabola sjukdomen i den vita befolkningen. I Sverige drabbar den ca 1:4500-6500 individer men i många länder har den en högre incidens på ca 1:2000-3000. Trots en klart förbättrad överlevnad det senaste decenniet är det fortfarande många som dör i ung ålder. Den vanligaste dödsorsaken är lungkomplikationer till följdCystic fibrosis (CF) is the most common severe autosomal recessive disorder among Caucasians and is caused by mutations of the chloride channel, CFTR (cystic fibrosis transmembrane conductance regulator) gene. Despite a markedly improved median survival many CF patients still die at a young age. The chronic lung disorder is the main cause of mortality. Endogenous and exogenous factors, which may c

Women’s Agency in Transforming Religious Discourse: Gender-Sensitive Interpretations of Islam in Indonesia

The purpose of this article is to present and analyse gender sensitive interpretations of Islam in Indonesia and a reform of fiqh from a gender perspective. These interpretations can be seen as an expression of Islamic feminism, a discursive framework that has grown from the Islamisation processes of Muslim societies in the 1980s. Another aim is to depict the specific Indonesian environment where

Classification of Wolf-Rayet stars in NGC 595 in M 33 through high-spatial resolution observations

NGC 595 is, after NGC 604, the second most luminous HII region in theMilky Ways neighbouring spiral galaxy M 33. Its Wolf-Rayet starcontent has mainly been unveiled by two different channels. On the onehand, the stellar population of NGC 595 has been resolved and its WRstars identified through on-line/off-line HeIIlambda4686 observationsrealised with the HST. Nevertheless, due to the limited numbe

Antigen-specific islet antibodies: prediction of beta cell failure and differentiation between Type 1 and Type 2 diabetes

Popular Abstract in Swedish Vid Typ 1 diabetes mellitus (insulinberoende, [ungdoms]) förlorar kroppen förmågan att tillverka insulin, det hormon som styr upptaget av socker i kroppens celler. Insulinet bildas av bukspottskörtelns hormonproducerande betaceller, och Typ 1 diabetes orsakas av att dessa celler skadas och förstörs. Denna skadeprocess anses idag i de flesta fall förmedlas av kroppens egAutoantibodies against glutamic acid decarboxylase (GADA), protein tyrosine-phosphatase-like protein (IAÐ2A), and/or pancreatic islet cells (ICA) are autoimmune markers usually present at diagnosis of Type 1 diabetes. Type 1 diabetes is therefore in general believed to be caused by an immune-mediated beta cell destruction. In children this destruction is fast, whereas in adult patients Type 1 diab

¿Una vivienda social incluyente en Liberia? El caso de una ciudad intermedia en Costa Rica

This article presents an empirical study, which analyzes the characteristics of those social housing projects implemented in the medium-sized city of Liberia, in Costa Rica, and their relationship to the territorial distribution of inequality and urban poverty. The dynamic economic growth of the province of Guanacaste and in particular of its capital, the city of Liberia, is widely recognized in C

Continuous-Time Identification

This chapter considers the problem of estimation of the transfer function of a continuous-time dynamic system in the presence of colored noise. Whereas parameter estimation can be made by means of a discrete-time maximum-likelihood algorithm, an operator transformation permits a continuous-time model parameterization. The method is useful in cases where it is important to estimate the coefficients

Welcome Home Mr Swanson : Swedish Emigrants and Swedishness on Film

Between 1840 and 1940, more than one million people emigrated from Sweden to America. The fact that so many chose to leave to seek a better life across the Atlantic was a major trauma for the Swedish nation. Filmmakers were not slow to pick up on an exodus that proved to be of lasting importance for the Swedes’ national identity. In Welcome Home Mr Swanson, film studies scholar Ann-Kristin Walleng

We drink with our eyes first: The web of sensory perceptions, aesthetic experiences and mixed imagery in wine reviews

This chapter analyzes the language resources that writers have at their disposal to describe their experience of the web of sensory perceptions that are evoked in the wine tasting practice. The task of the writer is to provide a mental understanding of the sensations as well as a prehension of the experiences. We show that this involves the weaving together of the senses, starting with the sight o

Safety as perceived by wheelchair-seated passengers in special transportation services

The aim of this study was to gain a better understanding of, and to help form a more complete picture of, the perceived safety of wheelchair-seated passengers using special transportation services (STS). A questionnaire was sent out and completed by 801 respondents in five Swedish regions. Additional information was acquired by means of 15 subsequent in-depth interviews. It was found that 5% repor

Proceedings utvecklingskonferens 09

I år var andra gången som Lunds universitet genomförde en universitetsgemensam pedagogisk utvecklingskonferens, första gången var 2007. Konferensen, som är ett samarrangemang mellan samtliga fakulteter och CED, har nu alltså blivit en återkommande aktivitet! Samhällsvetenskapliga fakulteten stod värd för årets konferens och dekanus Ann-Katrin Bäcklund sträckte vid invigningen fram en symbolisk sta

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Essän ägnas åt att skissera en möjligt utvecklingslinje för hur bilder av manskroppen skapats och/eller använts i en homosexuell kultur från sekelskiftet 1900 till idag, och hur detta bildbruk samverkat med en normaliserande och dominerande heterokultur.

Nitric Oxide Regulation during Anti-tumor Immunotherapy

Popular Abstract in Swedish Tumörer kan på olika sätt hämma immunsystemet och detta kan vara orsaken till varför immunterapi mot tumörer oftast inte lyckas. Denna nedreglering av immunförsvaret kan medieras av faktorer producerade från tumörcellerna själva eller så kan den följa efter en stark immunstimulering som satts igång av immunterapi. Kväve monoxid (NO) har visats vara en av de ämnen som kaDuring tumor progression a strong immunosuppression is developed and is believed to be the major reason why immunotherapy fails. This suppression is induced in response to factors produced from tumor cells, but can also be induced after immunotherapy. NO has been shown to play a major role in this suppression both in patients with gliomas and colon carcinomas. The aim of this thesis is to clarify

Postmodernism and the Digital Era

The concept ‘postmodernism’ refers to a very complex ideological movement concerning the entire cognitive field; from music to architecture, from film to philosophy and from technology to sociology. As an academic ‘subject’ or object of study, its origin can be dated to the midst of the 1980’s, but as a historical process, the dating is more difficult. Some writers associate the birth of postmoder