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Aim of the study: To assess the association of prevalence and size of pelvic sentinel node (SLN) metastases with risk factors in endometrial cancer (EC). Patients and Methods: Between June 2014 and January 2024 consecutive women with a uterine confined EC undergoing robotic surgery including detection of pelvic SLNs at a University Hospital were included. An anatomically based algorithm utilizing
Objective: Real-life management of hypertensive patients with chronic kidney disease (CKD) is unclear. Methods: A survey was conducted in 2023 by the European Society of Hypertension (ESH) to assess management of CKD patients referred to ESH-Hypertension Excellence Centres (ESH-ECs) at first referral visit. The questionnaire contained 64 questions with which ESH-ECs representatives were asked to e
A method is presented to reconstruct charged particles with lifetimes between 10ps and 10ns, which considers a combination of their decay products and the partial tracks created by the initial charged particle. Using the Ξ- baryon as a benchmark, the method is demonstrated with simulated events and proton-proton collision data at s=13TeV, corresponding to an integrated luminosity of 2.0fb-1 collec
Background: Neuroendocrine tumours (NETs) typically overexpress somatostatin receptors. By radiolabelling somatostatin analogues with a positron-emitting radionuclide (68Ga-DOTATOC or 68Ga-DOTATATE), these tumours can be detected with high sensitivity and specificity using somatostatin receptor positron emission tomography-computed tomography (PET-CT).Aim: To enhance knowledge about NETs imaged wi
Purpose: Different imaging tools, including digital breast tomosynthesis (DBT), are frequently used for evaluating tumor response during neoadjuvant chemotherapy (NACT). This study aimed to explore whether using artificial intelligence (AI) for serial DBT acquisitions during NACT for breast cancer can predict pathological complete response (pCR) after completion of NACT. Methods: A total of 149 wo
Objective: Targeted Health Dialogues (THD) is a public health intervention program that aims at preventing cardiovascular disease. THDs were implemented in the Swedish region Scania, in 2020, with the novelty of being conducted in a metropolitan area with a multiethnic population. This study investigated the prevalence of obesity among 40-year-old THD participants in Scania by region of birth, and
Purpose Visual interpretation of brain amyloid-β (Aβ) PET can be difficult in individuals with borderline Aβ burden. Coregistration with individual MRI is recommended in these cases, which, however, is not always available. This study evaluated coregistration with the early perfusion frames acquired immediately after tracer injection to support the visual interpretation of the late Aβ-frames in PE
The Varena Iron Ore deposit in the SW East European Craton is a significant ore body that occurs within metamorphosed and hydrothermally reworked Paleoproterozoic dolostones. We have performed microstructural investigations supplemented with mineral chemistry and geochronological investigations (LA-ICP-MS) to obtain age constraints on the ore-forming event(s) and improve the understanding of the c
Project report from Region Skåne, investigating how to improve evaluations of healthcare quality and equity in Region Skåne. Project duration 2022-2024.
Almost half of all divorced Swedes are aged 60+ and many of them are, or have been, part of a reconstituted family. This increases the probability of having (or to be a) bonus/step-grandchild and raises the question: How does the caregiving dynamic between bonus-grandparents and bonus-grandchildren intersect with gender and life situation, unraveling the intricate threads that weave through familiAlmost half of all divorced Swedes are aged 60+ and many of them are, or have been, part of a reconstituted family. This increases the probability of having (or to be a) bonus/step-grandchild and raises the question: How does the caregiving dynamic between bonus-grandparents and bonus-grandchildren intersect with gender and life situation, unraveling the intricate threads that weave through famili
Parkinson's disease (PD) is characterised by severe degeneration of dopamine (DA) neurons innervating the striatum. Spiny projection neurons (SPNs), are the principal type of striatal neuron and belong to either of two classes: the D2 receptor-positive indirect pathway SPNs (iSPNs) and the D1 receptor-positive direct pathway SPNs (dSPNs). The thesis aims at investigating dynamic changes of SPNs an
This paper develops new econometric methods for multiple structural break detection in panel data models with interactive fixed effects. The new methods include tests for the presence of structural breaks, estimators for the number of breaks and their location, and a method for constructing asymptotically valid break date confidence intervals. The new methodology is applied to a large panel of US
Introduction: Antimicrobial resistance (AMR) represents a persistent and ascensive global threat influenced by antibiotic misuse and overuse. In the Romanian context, patterns of antibiotic consumption and resistance within the healthcare system are marked in the red scenario on the European map. General practitioners and pharmacists, among others, play a major role in stewardship towards AMR.Aim:
AIMS: Impaired left ventricular-arterial coupling (VAC) has been shown to correlate with worse prognosis in cardiac diseases and heart failure (HF). The extent of the relationship between VAC and circulating biomarkers associated with HF has been scarcely documented. We aimed to explore associations of VAC with proteins involved in HF pathophysiology within a large population-based cohort of middl
BACKGROUND: Despite the detrimental impact of abnormal glucose metabolism on cardiovascular prognosis after myocardial infarction (MI), diabetes is both underdiagnosed and undertreated. We investigated associations between structured diabetes care routines in cardiac rehabilitation (CR) and detection and treatment of diabetes at one-year post-MI.METHODS: Center-level data was derived from the Perf
