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Clinical and experimental studies on wear and osteolysis in total joint replacement

Popular Abstract in Swedish Total höftledsplastik är en vanlig och mycket framgångsrik behandling av smärttillstånd i höftleden. Enligt svenska höftplastikregistret opererades 12651 patienter år 2002 men 1056 patienter fick samma år genomgå ett utbyte av sin höftledsprotes (revision). Att höftleden vrids ur led (luxation) upprepade gånger eller infektion kan vara orsaken till revision men det vanlTotal hip arthroplasty is a very successful procedure. Despite this fact, however, a certain portion of patients has to be revised. One major reason for revision is the wear of the polyethylene leading to loosening and osteolysis. The overall aim of this thesis was to evaluate linear wear and migration of cemented, all - polyethylene sockets and polyethylene liners in total hip arthroplasty. The a

Measurements of Turbulent Flame Speed and Integral Length Scales in a Lean Stationary Premixed Flame

Turbulent premixed natural gas - air flame velocities have been measured in a stationary axi-symmetric burner using LDA. The flame was stabilized by letting the flow retard toward a stagnation plate downstream of the burner exit. Turbulence was generated by letting the flow pass through a plate with drilled holes. Three different hole diameters were used, 3, 6 and 10 mm, in order to achieve differ

Precomputed local radiance transfer for real-time lighting design

This paper introduces a new method for real-time relighting of scenes illuminated by local light sources. We extend previous work on precomputed radiance transfer for distant lighting to local lighting by introducing the concept of unstructured light clouds. The unstructured light cloud enables a compact representation of local lights in the model and real-time rendering of complex models with ful

New single clock CMOS latches and flipflops with improved speed and power savings

New dynamic, semistatic, and fully static single-clock CMOS latches and flipflops are proposed. By removing the speed and power bottlenecks of the original true-single-phase clocking (TSPC) and the existing differential latches and flipflops, both delays and power consumptions are considerably reduced. For the nondifferential dynamic, the differential dynamic, the semistatic, and the fully static

Fragmentation of the lamellae and fractionation of polymer coils upon mixing poly(dimethylacrylamide) with the lamellar phase of aerosol OT in water

The lamellar mesophase formed by surfactant 1,4-bis(2-ethylhexyl) sodium sulfosuccinate (AOT) in deuterated water is mixed with poly(dimethylacrylamide) (PDMAA) polymers of low molecular weight ((M) over bar (n) = (2-20) x 10(3)). The mixtures separate into microphases (lamellar plus isotropic polymer solution). Their microstructures are studied by microscopy, small-angle X-ray scattering (SAXS),

Do partial and regular migrants differ in their responses to weather?

Partial migration is often considered a transitory stage between migration and residency, and whether partial migrants take weather conditions into account during migration is largely unknown. To assess whether partial migrants differ from regular migrants in their responses to weather, we compared the migratory intensity of a partial migrant, the Blue Tit (Cyanistes caeruleus), with more regular

Biological variation of retinoids in man.

This investigation was undertaken to assess biological variation, especially the within-subject variations of all- trans retinoic acid, 13- cis retinoic acid and retinol in human serum. Diurnal variation and variation over a week, a month and a year were studied in 11 males (aged 21 - 54 years) and 17 females (aged 22 - 63 years), all subjectively healthy. We found no diurnal variation with the ex

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Objective:To study the time response of fission neutrons induced apoptosis in murine thymocytes with 60 Co γ-rays as the reference radiation and to investigate preliminarily its molecular mechanism. Methods: Apoptosis induction was detected by means of DNA gel electrophoresis, morphologic assay, flow cytometric (FCM) analysis and diphenylamine(DPA) method respectively. p53 and bcl-2 gene expressio

Effects of gradual bone lengthening on the rabbit tibial nerve

Little is known about the effect of gradual bone lengthening on peripheral nerves. In the present study, an external fixation device was applied to the rabbit tibia, which was then divided. After seven days, the tibia was subjected to 0.7 mm/day callus distraction for periods of up to one month. The tibial nerve was fixed in glutaraldehyde and plastic sections were cut in longitudinal and transver

Increased tolerance and conversion of inhibitors in lignocellulosic hydrolysates by Saccharomyces cerevisiae

During hydrolysis of lignocellulosic biomass, monomeric sugars and a broad range of inhibitory compounds are formed and released. These inhibitors, which can be organized around three main groups, furans, weak acids and phenolics, reduce ethanol yield and productivity by affecting the microorganism performance during the fermentation step. Among the microorganisms that have been evaluated for lign

A genomic map of a 6-Mb region at 13q21-q22 implicated in cancer development: identification and characterization of candidate genes

Chromosomal region 13q21-q22 harbors a putative breast cancer susceptibility gene and has been implicated as a common site for somatic deletions in a variety of malignant tumors. We have built a complete physical clone contig for a region between D13S1308 and AFM220YE9 based on 18 yeast artificial chromosome and 81 bacterial artificial chromosome (BAC) clones linked together by 22 genetic markers