Using Swedish registers, we examine whether the prescription of and the response to antidepressants (AD), mood stabilizers (MS), and antipsychotics (AP) in the treatment of, respectively, major depression (MD), bipolar disorder (BD), and schizophrenia (SZ), are influenced by familial-genetic risk. We examined individuals born in Sweden 1960–1995 with a first diagnosis of MD (n = 257,177), BD (n =

The experience of heritage sites through digital technology is an increasingly important topic for researchers and practitioners. Drawing upon telepresence theory, this study explores how a visitor’s destination image is formed and its impact on satisfaction in a virtual heritage site experience. The survey results show that telepresence, cognitive image, affective image, and satisfaction are posi

PURPOSE: To investigate estimated delivered dose distributions using weekly cone-beam computed tomography (CBCT) scans for pelvic organs at risk (OARs) in salvage radiotherapy (SRT) after radical prostatectomy. Furthermore, to compare them with the originally planned dose distributions and analyse associations with gastrointestinal (GI) and genitourinary (GU) side effects.METHODS: This study is pa

Background Prior research has reported an association between divorce and suicide attempt. We aimed to clarify this complex relationship, considering sex differences, temporal factors, and underlying etiologic pathways. Methods We used Swedish longitudinal national registry data for a cohort born 1960-1990 that was registered as married between 1978 and 2018 (N = 1 601 075). We used Cox proportion

Vårt land har inte blivit rikt och fritt genom monopol och korporativism. Striden mellan LO och Tesla pekar på en central fråga: ska det svenska samhället vila på individorienterad grund eller starka särintressen?

The pair-distribution function, which provides information about correlations in a system of interacting particles, is one of the key objects of theoretical soft matter physics. In particular, it allows for microscopic insights into the phase behavior of active particles. While this function is by now well studied for two-dimensional active matter systems, the more complex and more realistic case

Introduction: Although ischemic stroke incidence has decreased in Sweden over the past decade, trends in spontaneous intracerebral hemorrhage (ICH) incidence are less well delineated. In this time period, there has been a dramatic increase in use of oral anticoagulants (OAC). The aim of our study was to investigate incidence trends in spontaneous first-ever ICH in Sweden between 2010 and 2019, wit

Objectives: The objective of this study was twofold: to determine the prevalence of arterial and venous thromboembolic events in the Norwegian Hereditary Hemorrhagic Telangiectasia (HHT) population, and to explore potential factors linked to such events, with particular emphasis on FVIII. Methods: Patients with an HHT diagnosis attending the Otorhinolaryngology Department at Oslo University Hospit

The fascination with the “Eastern Wisdom” exhibited among esoteric movements in the late nineteenth and early twentieth century is often understood as an interest in spirituality. Existing research has focused on how these movements took an interest in beliefs in doctrines like karma and reincarnation, as well as in practices of meditation and divination. Although this characterization is broadly

Background and aims: Previous study showed that elevated circulating hepatokine follistatin (FST) associates with an increased risk of type 2 diabetes by inducing adipose tissue insulin resistance. Here we explore further the relationships between plasma FST levels with mortality and health outcomes. Methods and results: The population-based Malmö Diet Cancer cardiovascular cohort (n = 4733, age 4

TP53 is the most frequently mutated gene in human cancer. This gene shows not only loss-of-function mutations but also recurrent missense mutations with gain-of-function activity. We have studied the primary bone malignancy osteosarcoma, which harbours one of the most rearranged genomes of all cancers. This is odd since it primarily affects children and adolescents who have not lived the long life

Aim: The study aimed to explore the experiences of care and recovery among older patients treated for physical trauma. Design: A qualitative study with a constructivist grounded theory design. Methods: Fifteen in-depth interviews with older adults recovering from physical trauma were conducted and analysed between 2019 and 2023, in accordance with grounded theory methodology. Results: The findings

Purpose: The use of molecular radiotherapy (MRT) has been rapidly evolving over the last years. The aim of this study was to assess the current implementation of dosimetry for MRTs in Europe. Methods: A web-based questionnaire was open for treating centres between April and June 2022, and focused on 2020–2022. Questions addressed the application of 16 different MRTs, the availability and involveme

Shocked zircon from impactites from the Mien impact structure, Sweden, has been investigated with the aim to date the impact event and correlate the degree of U–Pb age resetting with shock-related microtextures. In situ U–Pb spot isotope analyses of granular and microporous–granular zircon grains from the impact melt rocks give an age of 120.0 ± 1.0 Ma. This essentially confirms the previous best

What is the purpose of lengthy negotiations when a coalition government forms? Do they make a difference in coalition policy-making? Negotiations that produce policy agreements between coalition partners have been suggested to strengthen the capacity of coalition governments to make policy reforms. We argue that bargaining time, regardless if it results in a written policy agreement or not, is an

In most non-fullerene organic solar cells comprising bulk-heterojunction active layers, the inter-domain connectivity of small-molecule acceptors is generally inferior to those of polymeric donors due to their intrinsic short-range ordering. This issue is even exacerbated by the physiochemical mismatch between acceptor-phases and metal-oxide electron transport layers in most inverted n-i-p devices

This paper aims to foreground the importance of emotions in water diplomacy in general and in Nile water diplomacy in particular. Water diplomacy does not operate from a clean slate, but in a socio-hydropolitically mediated context which is, in turn, imbued with emotions. The existing water diplomacy approach primarily operates with the assumption that the riparian state is a rational actor. Howev