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Background: The aim was to evaluate data quality and psychometric properties of an instrument for measurement of health-related quality of life: DISABKIDS Chronic Generic Module (DCGM-37) used in school-aged children with cancer. Methods: All school-children diagnosed with cancer in Sweden during a two-and-a-half year period were invited to participate in the study. Analysis was performed on combi

Popular Abstract in Swedish Bakgrund: Nio av tio patienter som läggs in på sjukhus efter hjärtstillestånd utanför sjukhus är medvetslösa och behöver intensivvård. Dödligheten och risken för varaktiga hjärnskador är stor. Förhöjd kroppstemperatur under intensivvården är förenat med sämre överlevnad och hjärnfunktion. Nedkylning har i djurexperimentella och preliminära kliniska studier visat sig varThis thesis is based on studies of the clinical use of induced hypothermia as an intervention to reduce mortality and neurological impairment after cardiac arrest. After the publication of two trials indicating benefit of induced hypothermia, we developed a registry to assess outcome, possible adverse events and conduct of induced hypothermia when this intervention was implemented in a clinical p

The brilliance of modern synchrotron radiation sources and capabilities of new instrumentation facilitate resonant inelastic soft X-ray scattering of liquids and molecular materials with high spectral quality. Especially, when the energy resolution approaches the natural line widths a detailed analysis provides information about local potential surfaces, dynamic coupling between nuclear and electr

A series of recent studies have provided initial evidence about the role of specific intra-molecular interactions in maintaining proteins in their soluble state and in protecting them from aggregation. Here we show that the amino acid sequence of the protein monellin contains two aggregation-prone regions that are prevented from initiating aggregation by multiple non-covalent interactions that fav

Abstract Objective: To assess the cost-effectiveness of insulin detemir compared with Neutral Protamine Hagedorn (NPH) insulin when initiating insulin treatment in people with type 2 diabetes mellitus (T2DM) in Denmark, Finland, Norway, and Sweden. Methods: Efficacy and safety data were derived from a 20-week multi-centre randomized controlled head-to-head clinical trial comparing insulin detemir

Macroinvertebrates and fish in the contaminated river are faced with a higher risk to suffer from exposure to Hg than humans eating contaminated fish and bacteria living in the groundwater. The river sediment is the most hazardous source for the macroinvertebrates, and macroinvertebrates make up the highest risk for fish. The distribution of body concentrations of Hg in fish in the mining areas of

The walrus (Odobenus rosmarus) is in some current systematic schemes divided into three subspecies: O. r. rosmarus in the North Atlantic, O. r. divergens in the North Pacific and O. r. laptevi in the Laptev Sea. These three subspecies have been described as differing in body size, but the taxonomic status of O. r. laptevi is disputed. The current study applies molecular and morphometric methods to

How professions should be defined and separated from other occupations has constituted an enduring theoretical and empirical problem in studies of the professions. In this article, the definitions of the so-called list approaches, involving enumerations of social attributes, are scrutinized. Weak-nesses are highlighted and analysed. It is argued that an alternative approach to the issue of definit

Retinopathy of prematurity (ROP) is a sight-threatening disease, requiring efficient screening and treatment. The present study aims to describe various aspects on treatment for ROP in Sweden.

Background. The leucine-rich repeats and immunoglobulin-like domains (LRIG) family of transmembrane proteins are involved in the regulation of cellular signal transduction. LRIG1 is an endogenous inhibitor of receptor tyrosine kinases (RTKs) and an emerging tumor suppressor. In the lung epithelium, the expression of LRIG1 is downregulated by tobacco smoking, and further downregulated in lung squam

The cover of the latest volume of the scientific flora Flora Nordica (2010) is illustrated with a picture of the mezereon plant, Daphne mezereum, taken from J. W. Palmstruch’s old Swedish flora Svensk botanik (1802). In his preface, Palmstruch states that the illustrations are most often depicted from nature, but ”sometimes borrowed, with or without improvements” from four quoted international wor

As n-ary operations, generalizing Lie and Poisson algebras, arise in many different physical contexts, it is interesting to study general ways of constructing explicit realizations of such multilinear structures. Generically, they describe the dynamics of a physical system, and there is a need of understanding their quantization. Hom-Nambu-Lie algebras provide a framework that might be an appropri

Radiochromic film, polymer gel and radiochromic plastic are three different kinds of dosimeters developed for radiation therapy and suitable for optical readout. In this study, different optical CT scanners are used to scan the dosimeters to find out if they could be used as multi-purpose scanners, i.e. for readout of the different kinds of dosimeters. Promising results are found but further devel

Aims and objectives. To investigate the factors that influence satisfaction with emergency care among individuals accompanying patients to the emergency department and explore agreement between the triage nurse and accompanying person regarding urgency. Background. Many patients seeking treatment in hospital are escorted by an accompanying person, who may be a friend, family member or carer. Sever

The transverse momentum(p(T)) spectrum and nuclear modification factor (R-AA) of reconstructed jets in 0-10% and 10-30% central Pb-Pb collisions at root s(NN) = 2.76 TeV were measured. Jets were reconstructed using the anti-k(T) jet algorithm with a resolution parameter of R = 0.2 from charged and neutral particles, utilizing the ALICE tracking detectors and Electromagnetic Calorimeter (EMCal). Th