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Educational inequalities in mortality associated with rheumatoid arthritis and other musculoskeletal disorders in Sweden

BACKGROUND: Musculoskeletal (MSK) disorders are less likely to be reported as an underlying cause of death (UCD) and since cause of death studies are generally limited to the UCD, little is known about socioeconomic inequalities in MSK disorders as cause of death in the general population. Using multiple-cause-of-death data, we aimed to quantify and compare educational inequalities in musculoskele

Ammonia measurements with femtosecond laser-induced plasma spectroscopy

Femtosecond laser-induced plasma spectroscopy for in situ ammonia (NH 3 ) measurements was demonstrated in NH 3 ∕N 2 mixtures. When a femtosecond laser at 800 nm was focused at the flow field, the parent NH 3 molecules would be photolyzed to generate electronics excited NH fragments, and then indirect measurements of NH 3 could be realized by detecting the NH fluorescence (A 3 Π − X 3 Σ −

Proteinase-3 and myeloperoxidase serotype in relation to demographic factors and geographic distribution in anti-neutrophil cytoplasmic antibody-associated glomerulonephritis

Background: In anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis, antigen specificity varies between myeloperoxidase (MPO) and proteinase 3 (PR3). This has been reported to vary in relation to age, gender, geography and extrarenal manifestations. However, studies are difficult to compare as criteria for inclusion vary. The aim of this study was to investigate the relationsh

Disentangling the genetics of lean mass

Background: Lean body mass (LM) plays an important role in mobility and metabolic function. We previously identified five loci associated with LM adjusted for fat mass in kilograms. Such an adjustment may reduce the power to identify genetic signals having an association with both lean mass and fat mass. Objectives: To determine the impact of different fat mass adjustments on genetic architecture

In situ calibration of large-radius jet energy and mass in 13 TeV proton–proton collisions with the ATLAS detector

The response of the ATLAS detector to large-radius jets is measured in situ using 36.2 fb - 1 of s=13 TeV proton–proton collisions provided by the LHC and recorded by the ATLAS experiment during 2015 and 2016. The jet energy scale is measured in events where the jet recoils against a reference object, which can be either a calibrated photon, a reconstructed Z boson, or a system of well-measured sm

Clinical implications of different risk factor profiles in patients with mesenteric venous thrombosis and systemic venous thromboembolism : a population-based study

It is unknown whether the risk factor profile for mesenteric venous thrombosis (MVT) is different from systemic venous thromboembolism (VTE). The aim of the present population-based study was to compare acquired and inherited risk factors in MVT versus VTE. Identification of all MVT patients at Skåne University Hospital between 2000 and 2015 was performed in patient records and AuriculA (Swedish a

Improved outcome with standardized plan for clinical management of acute decompensated chronic heart failure

Background Our overall goal is to improve clinical care for inpatients with chronic heart failure (CHF). A retrospective assessment of CHF patients admitted to our hospital over the past decade (2005 vs. 2014) indicated a need for better strategies to evaluate clinical treatment, implement best practices and achieve optimal patient outcome. To that purpose, we developed a standardized plan to impr

Decontamination after a nuclear fallout: A condensed review of case studies, methods and key references up to 2014

The objective of this work is to provide governmental agencies and the society a condensed overview of the current state of knowledge on the efficiency of applied restoration and remediation of areas affected by radioactive fallout. The most actual real-world case is the Fukushima accident in Japan in 2011: the accident and the following applied decontamination methods are in focus in this review

Stråldosen till boende i nedfallsdrabbade områden: Preliminära uppskattningar efter svenska förhållanden

Utifrån modeller som tagits fram efter radioekologiska studier av svenska förhållanden utförda efter Tjernobylolyckan 1986 visar preliminära beräkningar att de avstyrda stråldoser som kan åstadkommas med sanering av byggnadshus respektive strikta livsmedelsrestriktioner är relativt lika (ca 25%). En kombination av dessa åtgärder kan teoretiskt sänka den summerade stråldosen med 50% under ett 50-år

Microstructural white matter alterations associated to neurocognitive deficits in childhood leukemia survivors treated with cranial radiotherapy–a diffusional kurtosis study

Background: Cranial radiotherapy (CRT) is a known risk factor for neurocognitive impairment in survivors of childhood acute lymphoblastic leukemia (ALL). Diffusion tensor imaging (DTI) and diffusional kurtosis imaging (DKI) are MRI techniques that quantify microstructural changes in brain white matter (WM) and DKI is regarded as the more sensitive of them. Our aim was to more thoroughly understand

Long-term follow-up study of low-weight avoidant restrictive food intake disorder compared with childhood-onset anorexia nervosa : Psychiatric and occupational outcome in 56 patients

Objective: To compare long term outcome between childhood-onset Anorexia Nervosa (AN) and low-weight Avoidant/Restrictive Food Intake Disorder (ARFID) in regard to psychiatric diagnoses, social and occupational functioning. Method: A consecutive series of 56 children originally treated for low-weight restrictive eating disorder (ED) were followed up after a mean of 15.9 years. ARFID-diagnoses were

Exosomes in Parkinson's Disease : Current Perspectives and Future Challenges

Exosomes, which are lipid bilayer membrane vesicles, have been implicated as carriers of biological macromolecules. In recent years, the functions of exosomes in the spreading of pathological conversion of proteins among neurons have drawn particular attention in Parkinson's disease research. Extracellular α-synuclein is proven to be associated with exosomes in vivo and in vitro. The contents of t

Increased antibody levels to stage-specific Epstein–Barr virus antigens in systemic autoimmune diseases reveal a common pathology

The immune responses to antigens from different stages of the Epstein–Barr virus (EBV) life cycle were investigated in systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren’s syndrome (SS), and systemic sclerosis (SSc) to gain knowledge of EBV’s involvement in the etiology of systemic autoimmune diseases (SADs) and for an overview of the humoral immune responses against EBV. Inves

The impact of an individualised neonatal parent support programme on parental stress : a quasi-experimental study

Aim: To evaluate the impact on parental stress of an individualised neonatal parent support programme. Method: A quasi-experimental design. Parents of preterm infants, at a level II NICU, were consecutively assigned to a control group (n = 130) and to an intervention group (n = 101). The programme focused on person-centred communication and consisted of four individual nurse–parent dialogues durin

Effect of diabetes mellitus on the recovery of changes in renal functions and glomerular permeability following reversible 24-hour unilateral ureteral obstruction

Background: Following reversal of short periods of ureteral obstruction (UO), glomerular and tubular renal dysfunction recovers with time. Diabetes mellitus (DM) affects glomerular function; thus, the ability of diabetic kidneys to recover from UO may be impaired. This study investigated the effects of long-term DM on the recovery of glomerular and tubular function, as well as permeability of the

End-Stage Kidney Diseases in Immigrant Groups : A Nationwide Cohort Study in Sweden

Background: Our aim was to study the association between the country of birth and incident end-stage kidney disease (ESKD) in several immigrant groups in Sweden, using individuals born in Sweden or with Swedish-born parents as referents. Methods: A cohort study of first- and second-generation immigrants residing in Sweden between January 1, 1998 and December 31, 2012 was performed. Outcomes were d

Weak effects of farming practices corresponding to agricultural greening measures on farmland bird diversity in boreal landscapes

Context: The current Common Agricultural Policy (CAP) of the European Union includes three greening measures, which are partly intended to benefit farmland biodiversity. However, the relative biodiversity effects of the greening measures, including joint effects of landscape context, are not well understood. Objectives: We studied the effects of increasing crop diversity, proportions of production