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Highlights of the São Paulo ISEV workshop on extracellular vesicles in cross-kingdom communication

In the past years, extracellular vesicles (EVs) have become an important field of research since EVs have been found to play a central role in biological processes. In pathogens, EVs are involved in several events during the host–pathogen interaction, including invasion, immunomodulation, and pathology as well as parasite–parasite communication. In this report, we summarised the role of EVs in inf

Evidence for Two Levels of Intimate Partner Violence and Aggression Among Incarcerated Young Male Violent Offenders

Furthering knowledge of the subset of incarcerated partner violent offenders distinguished by aggression, anger, and hostility is relevant, as these offenders are guilty of the more severe kinds of intimate partner violence (IPV). Our aim was to identify groups with different patterns of IPV among convicted young Swedish male offenders, using data from the Development of Aggressive Antisocial Beha

An attenuation method for reducing count rate losses in preclinical PET during intratherapeutic imaging

In pre-clinical imaging, tumor response to radionuclide therapy can be monitored with PET imaging. Radionuclides used for therapy such as 177Lu emit a significant amount of low energy photons. These photons may have an energy high enough to penetrate the imaged object and are the prone to be detected. Although these phtons are likely to be rejected electronically, they add dead-time to the system

Genotype-based recall to study metabolic effects of genetic variation : a pilot study of PPARG Pro12Ala carriers

Aim: To assess practical implications of genotype-based recall (GBR) studies, an increasingly popular approach for in-depth characterization of genotype–phenotype relationships. Methods: We genotyped 2500 participants from the Swedish EpiHealth cohort and considered loss-of-function and missense variants in genes with relation to cardiometabolic traits as the basis for our GBR study. Therefore, we

Changes in blood volume shunting in patients with atrial septal defects : Assessment of heart function with cardiovascular magnetic resonance during dobutamine stress

Background: The purpose of this study was to determine the effect of stress on left-to-right shunting in patients with atrial septal defect (ASD) and to investigate if the degree of shunting, cardiac output (CO), and right ventricular (RV) volumes are related to exercise capacity. Methods: Twenty-six patients with a secundum ASD and 16 healthy volunteers were studied with rest/stress cardiac magne

Promoting sustainable travel behaviour through the use of smartphone applications: A review and development of a conceptual model

The negative effects of transport in terms of pollution, congestion and climate change has urged the need for higher shares of cleaner and more efficient modes of transport, especially in urban settings. While new tech- nology can solve some of these issues, behaviour changes has also been identified as an important factor to achieve a modal shift from cars to walking, cycling or public transport.The negative effects of transport in terms of pollution, congestion and climate change has urged the need for higher shares of cleaner and more efficient modes of transport, especially in urban settings. While new technologycan solve some of these issues, behaviour changes has also been identified as an important factor to achieve a modal shift from cars to walking, cycling or public transport. Th

Factors Predicting the Off-treatment Duration in Patients with Prostate Cancer Receiving Degarelix as Intermittent Androgen Deprivation Therapy

Background: Intermittent androgen deprivation therapy (IAD) is commonly used in prostate cancer because of the benefits of the off-treatment period (OTP). The off-treatment time for patients depends on cancer progression, often measured as a rise in prostate-specific antigen (PSA). Objective: To evaluate if certain factors can predict OTP duration following 7-mo degarelix therapy. Design, setting,

Designing Scandinavia: A Cultural Semiotics Approach to Dialogic Image making.

Evaluations of the other culture is a strong force, not only in cultural dialogue but, consequently, in a culture’s formation of itself. Cultures are formed, as it were, in encounters that include domination, conflict, and dismissal as much as appreciation and smooth exchange. In this paper, the construction of cultural identity is discussed, in a study of a Scandinavian Theme Park proposal that w

Cultural adaptation and validation of the Swedish VEINES-QOL/Sym in patients with venous insufficiency

Objectives: To translate and evaluate the psychometric properties of the Venous Insufficiency Epidemiological and Economic Studies (VEINES) questionnaire, divided into two subscales; symptoms (VEINES-Sym) and quality of life (VEINES-QOL), in a Swedish cohort of patients with venous disease. Methods: The original questionnaire was translated into Swedish with forward–backward translation and admini

Genomskinligheten

Short afterword to an edition with the poem "Ett glas vatten" ("A Glass of Water") from 1966, by Swedish poet Lasse Söderberg (b. 1931).

New Directions in Judicial Review? Proportionality, Subsidiarity and Impact Assessment in the Tobacco Product Directive Case

In this essay in honour of Christina Moëll, we focus on one particular recent case: the Philip Morris case delivered in May 2016 where the European Court of Justice (ECJ) rules on the validity of the Tobacco Product Directive case.1 It is a key case on the application of the principle of proportionality but not only since it connects this principle with other constitutional principles putting limi