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Hemoglobin (Hb)-based oxygen carriers (HBOC) have been engineered to replace or augment the oxygen-carrying capacity of erythrocytes. However, clinical results have generally been disappointing due to adverse side effects linked to intrinsic hememediated oxidative toxicity and nitric oxide (NO) scavenging. Redox-Active tyrosine residues can facilitate electron transfer between endogenous antioxida

We obtained osmotic pressure data of lysozyme solutions, describing their physical states over a wide concentration range, using osmotic stress for pressures between 0.05 bar and about 40 bar and volume fractions between 0.01 and 0.61. The osmotic pressure vs. volume fraction data consist of a dilute, gas-phase regime, a transition regime with a high-compressibility plateau, and a concentrated reg

A new subporphyrin was synthesized for use as a molecular sensitizer in electrochemical and dye-sensitized photoelectrochemical water oxidation. A photoelectrochemical cell with a TiO2 electrode modified with the sensitizer and a molecular water oxidation catalyst generated higher photocurrent than reference cells that have electrodes modified with either the photosensitizer or the catalyst under

Natural hazards such as landslides, floods, rockfalls, earthquakes, volcanic eruptions, sinkholes, and snow avalanches represent potential risks to our infrastructures, properties, and lives. That potential will continue to escalate with current and continued human encroachment into risk areas. With the help of geophysical techniques many of those risks can be better understood and quantified, the

Organic-inorganic halide CH3NH3PbI3 (MAPbI3) perovskite solar cells (PSCs) have attracted intensive attention due to their high power conversion efficiency and low fabrication cost. However, MAPbI3 is known to be very sensitive to humidity, and the intrinsic long-term stability of the MAPbI3 film remains a critical challenge. 2-Aminoethanethiol (2-AET) was used as a ligand to bridge the organic co

We report on our studies of the neutron-skin effects in high-pT observables at the LHC. We study the impact of the neutron-skin effect on the centrality dependence of inclusive direct photon, highpT hadron and W± production in nuclear collisions at the LHC. The neutron-skin effect refers to the observation that in spherical heavy nuclei, the tail of the neutron distribution extends farther than th

Dutch elm disease (DED), caused by the fungi Ophiostoma ulmi and O. novo-ulmi, has reduced elm populations severely in Europe and North America. Breeding programmes are in action to find less susceptible elm varieties suitable for re-establishing elm stands. Bark beetles, mainly Scolytus spp., are the only known natural vectors of DED. During twig feeding, beetles transfer Ophiostoma spores to hea

The paper presents an interdisciplinary study in the field of automatic gender and age identification, under the scope of sociolinguistic knowledge on gendered and age linguistic choices that social media users make. The authors investigated and gathered standard and novel text features used in text mining approaches on the author’s demographic information and profiling and they examined their eff

I de nordiska länderna betraktades jesuiterna av tradition som själva sinnebilden för den ”katolska faran” och för allt det onda som av hävd förknippades med katolicismen. Men trots det var det just jesuiterna som drog till sig flest konvertiter, och ”jesuitförsamlingarna” fungerade som dragplåster för intresserade protestanter. Vad var förklaringen till detta? Hur såg man på konversioner i den ka

The inclusive and exclusive processes associated with a leading neutron in ep collisions at high energies are described using the color dipole formalism. We demonstrate that the available experimental HERA data on the xL (Feynman momentum) distribution of leading neutrons can be very well described taking into account the nonlinear (saturation) effects in the QCD dynamics. Moreover, we present our

Characterization of highly duplicated genes, such as genes of the major histocompatibility complex (MHC), where multiple loci often co-amplify, has until recently been hindered by insufficient read depths per amplicon. Here, we used ultra-deep Illumina sequencing to resolve genotypes at exon 3 of MHC class I genes in the sedge warbler (Acrocephalus schoenobaenus). We sequenced 24 individuals in tw

We report a solid smectic phase that exhibits dodecagonal global order. It is composed of axially stacked hexagonally ordered particle layers, and its 12-fold rotational symmetry induced by the 30° rotation of adjacent layers with respect to each other. A quasicrystal was produced in a molecular-dynamics simulation of a single-component system of particles interacting via a spherically-symmetric p

We present a spectral and inverse spectral theory for the zero dispersion spectral problem associated with the Camassa-Holm equation. This is an alternative approach to that in [10] by Eckhardt and Teschl.

Angiogenesis provides growing tumors a source of nutrients and oxygen, and a route for metastatic dissemination. In recent years anti-angiogenic therapies that primarily target the vascular endothelial growth factor (VEGF) signaling cascade have entered the clinic. However in practice, these have encountered unexpected mechanisms of resistance in many solid tumors, highlighting the need for furthe

Background: Everyday life in a family with a young person with attention-deficit/hyperactivity disorder (ADHD) and/or autism spectrum disorder (ASD), is multifaceted and may be a burden to the caregivers. The aim was to explore experiences of the caregiver situation, and how they were affected when the young persons received Internet-Based Support and Coaching (IBSC). Method: A multiple descriptiv

Background Evidence for treating infantile colic with acupuncture is contradictory. Aim To evaluate and compare the effect of two types of acupuncture versus no acupuncture in infants with colic in public child health centres (CHCs). Methods A multicentre, randomised controlled, single-blind, three-armed trial (ACU-COL) comparing two styles of acupuncture with no acupuncture, as an adjunct to stan