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Sammanfattning Kapitel 2 Presentation av ett nytt tumör-behandlingskoncept med ”Pre-kirurgisk intermittent ultrahypofraktionerad strålbehandling” (PSiRT) ”kombinerad med immunterapi” (PSiRIT), särskilt immun¬kontrollpunktshämmare (anti-CTLA4 och anti-PD-1).Intermittent ultrahypofraktionerad strålbehandling innebär:• Optimal absorberad dos 6–8 Gy per fraktion • Doser >10 Gy kan öka immunosuppress
This chapter highlights the centrality of atmospheres in tightly controlled environments like courtrooms and youth detention homes. In courtrooms, social control is achieved through affective arrangements, such as reading emotional cues and using touch or its avoidance to manage order. Legal professionals rely on their ability to sense and act on shifting atmospheres as part of their implicit skil
Critical events frequently occur in hospital settings. Cinematic portrayals of medicine and medical environments can illuminate historical developments and perspectives on healthcare, medical professions, and specialisations. This article aimed to explore the interplay between structural framework, professional, and relational factors when facing critical events and their management in a hospital
BackgroundTo educate students and prepare them for life in society, school principals, teachers, and staff need proper work-related organizational preconditions, motivation, and good health. In this context, span of control (SoC, i.e., the number of employees a manager is accountable for) is an understudied modifiable organizational precondition that influences the relationships between managers a
Streptococcus pneumoniae resists host defenses through multiple surface factors, yet their specific contribution to protection against antimicrobial peptides remains incompletely understood. We examined the role of pneumococcal surface protein A (PspA) and the polysaccharide capsule in protection against the human defensin HNP-1. PspA conferred increased resistance to HNP-1-induced killing, show
Background: Helicobacter pylori (Hp) and its virulence factor Cytotoxin-associated gene A (CagA) have been linked to myocardial infarction (MI), but the mechanisms are unknown. This study aims to test if Hp infection and CagA are associated with pre-specified inflammatory and vascular biomarkers in patients with MI and to explore whether a broader biomarker panel can predict infection. Furthermore
This study investigated the retention of spatial knowledge in buildings following route-learning training in a virtual reality environment. A total of 121 participants were tested up to three months later on putting waypoints of the route in the correct order and recalling directions at waypoints. Memory accuracy declined over time, consistent with classic memory theory. Route knowledge was retain
We present the design and implementation of a portable transfer system equipped with an integrated electrochemical cell that enables the controlled transfer of samples between an electrochemical environment and an ultrahigh vacuum (UHV) system without air exposure. This setup allows for the preparation of well-defined model surfaces, their electrochemical modification, and subsequent structural an
This study presents high-fidelity Large Eddy Simulations (LES) of supersonic combustion in a Mach 2 cavity flameholder over the full stable fueling region from 40 to 200 slpm. The simulations employ Finite Rate Chemistry LES with the Z70 ethylene-air mechanism, the Localized Dynamic k-equation model, Partially Stirred Reactor turbulence-chemistry interaction model, conjugate heat transfer, and the
The shape of reef-building corals largely determines how they interact with their environment and the ecosystem services they provide. However, morphology is not fixed. As corals grow and develop from singular polyps to mature adult colonies, they experience pronounced changes in their morphology. This developmental trait variation remains poorly quantified in corals, despite their importance as e
The sheet metal forming process is integral to the automotive industry, producing a variety of components essential for vehicle construction, including body panels, chassis parts, and structural supports. The process involves shaping thin metal sheets into desired forms using techniques such as bending, stretching, drawing, and stamping. In order to build high quality cars it is vital with an effi
Background All hospital laboratories in Sweden use the Owren prothrombin time (PT) method primarily to monitor anticoagulant treatment. Direct international normalized ratio (INR) calibration was introduced in 1999 under the supervision of Equalis, the national organization for external quality assessment (EQA) in laboratory medicine. Objectives We present 25 years of combined experience in develo
We unbox developments in artificial intelligence (AI) to estimate how exposure tothese developments affect firm-level labour demand, using detailed register data from Denmark, Portugal and Sweden over two decades. Based on data on AI capabilities and occupational work content, we develop and validate a time-variant measure for occupational exposure to AI across subdomains of AI, such as language moWe unbox developments in artificial intelligence (AI) to estimate how exposure to these developments affect firm-level labour demand, using detailed register data from Denmark, Portugal and Sweden over two decades. Based on data on AI capabilities and occupational work content, we develop and validate a time-variant measure for occupational exposure to AI across subdomains of AI, such as language
Case study research plays an important role for social and political scientists working within the qualitative tradition, with the field of international relations (IR) being no exception. This article provides methodological reflections on the challenges of investigating ‘elusive’ cases within the global governance domain of IR. Taking stock of my experience of studying global multi-stakeholder p
