Långverkande läkemedel har blivit allt viktigare i behandlingen av kroniska sjukdomar då det minskar behovet av frekvent dosering och kan på så sätt förbättra livskvaliteten hos patienter. Camurus är ett läkemedelsföretag i Lund som utvecklar sådana läkemedel med hjälp av sin FluidCrystal®-teknologi. Det är en injicerbar formulering som bildar en gel när den kommer i kontakt med vatten eller kroppIn recent years, long-acting drugs have emerged as a significant advancement in the treatment of chronic diseases. Camurus is a pharmaceutical company specializing in this area, with products based on FluidCrystal® technology—a lipid-based injectable drug delivery technology that, upon contact with water or physiological fluids, undergoes a phase transition into a liquid crystalline gel depot. Dru

The inauguration of President Trump in 2025 led to drastic changes in the U.S. market, notably great political as well as economical risks and uncertainties. The U.S. equity market was struck heavily by the policies, which also heavily affected global equity markets. In this case study, we study a long-short, market-neutral hedge fund situated in London, specifically HAFP (a pseudonym for the inte

The aim of this study is to identify what the relationship between ESG scores and capital structure is, and whether it differs depending on the selected capital structure measure. Building on previous literature on sustainability strategies and capital structure, this paper revises the current state of the interconnectivity between ESG and financing decisions. By employing a quantitative study wit

As markets become increasingly fierce in competition and rapid shifts disrupt the market dynamics, the pressure on firms to be able to adapt their business models and strategies has become a crucial aspect. The thesis adopts a qualitative multiple case study approach where the purpose is to investigate how firms are adapting their business models through dynamic capabilities in the plant-based ind

This thesis examines the development Forest Green Rovers has undergone since their current owner and Chairman joined the club. With a clear vision and agenda, the aim was to over time transform the club into something greater than just sporting achievements. For nearly fifteen years, the club's management has been dedicated to embedding sustainability in all aspects of the club's operation

This study examines the potential overlap between fear of retaliation and moral disengagement as explanations for peer bystander inaction in school bullying. Although typically seen as distinct barriers to peer intervention, the study investigates whether fear of retaliation can function as a moral disengagement mechanism, and whether fear-based and disengagement-based justifications are empirical

Mental Imagery (MI) allows us to simulate real-life experiences and visualise events we have never witnessed, but what happens when we change the language of the narrative? This study investigated how language context (L1 vs. L2) influences the vividness of mental imagery and the emotional intensity associated with that imagery during narrative comprehension. A total of 58 sequential bilinguals fr

This meta-analysis and systematic review examined the effects of psychedelic substances on death anxiety, specifically evaluating whether psychedelic experiences are associated with statistically significant reductions in death anxiety. Studies were eligible if they quantitatively assessed death anxiety or death acceptance using validated measures, or qualitatively explored attitudes toward death

Aims: More than 90% of patients with left bundle branch block (LBBB) and reduced left ventricular (LV) ejection fraction have LV dyssynchrony and a high probability of response to cardiac resynchronization therapy (CRT). A subgroup of patients with non-specific intraventricular conduction delay (IVCD) have a LBBB-like LV activation pattern when studied using invasive mapping and advanced echocardi

The regional variety of actors is considered a key determinant in the last decade's rich literature on the geography of eco-innovation and green regional development. However, little is known about the extent to which regions differ in their specialization in new and established eco-innovation actors. In this article, we propose a regional typology based on green specializations concerning both in

Background and hypothesis: KDIGO recommends proteinuria 30% eGFR decline. Compared with uACR < 0.3 g/g, any higher uACR category was strongly and incrementally associated with the risk of MAKE [adjusted hazard ratios (HR) ranging from 1.56 (95%CI 1.14-2.14) if uACR 0.3-0.5 g/g to 4.53 (3.36-6.11) if uACR ≥ 2.0 g/g], KRT (HR ranging from 1.39 to 4.65), and eGFR decline >30% (HR ranging from 1.76 to

Conventional dendritic cells (cDCs) are potent antigen-presenting cells (APCs) that integrate signals from their environment allowing them to direct situation-adapted immunity. Thereby they harbor great potential for being targeted in vaccination, autoimmunity, and cancer. Here, we use fate mapping, functional analyses, and comparative cross-species transcriptomics to show that RORγt+ DCs are a co

Background In congenital aortic stenosis (CAS), commissurotomy is an option in patients not suitable to receive a valve prosthesis. However, there is often a need for future additional interventions on the aortic valve. The fate of the aortic valve is, however, essentially unknown. This study reports the need for reinterventions after surgical commissurotomy, based on a national register. Material

Objectives: In SLE, anti-dsDNA can co-occur with autoantibodies against other chromatin components, like histones and nucleosomes. These antibodies induce type-1 interferon production, a hallmark of SLE. We measured ANA sub-specificities and investigated their associations to inflammatory biomarkers including interferon-regulated chemokines. Methods: We included 93 Sudanese and 480 Swedish SLE pat

The recycling and reuse of trace uranium from spent nuclear fuel is of great significance for the safety management of the nuclear fuel cycle. However, stabilization of low-valent uranium has always been a challenge due to the ultraoxidizable nature of uranium ions, which remains relatively uncharted territory in spent fuel treatment. In the current study, U4+ was immobilized in Cs2UCl6 single cry

Sveriges växande befolkning har lett till ökad efterfrågan på byggprojekt, men byggsektorns produktivitet har inte utvecklats i samma takt. För att möta framtidens behov krävs effektivare arbetssätt, där valet av affärsform, det vill säga kombinationen av entreprenadform, ersättningsmodell och samarbetsform, har en central betydelse. En väl anpassad affärsform kan bidra till bättre samarbete, högr

This study investigates the activist engagement strategies of U.S.-domiciled hedge funds when engaging with Japanese firms. The study forms a comparison of the engagement strategies both before Japan’s 2015 Corporate Governance Code and after. To create this comparison, two campaigns were examined. First, the U.S.-domiciled hedge fund Steel Partners and its campaign against Japanese firm Bull-Dog