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Mass spectrometry and site-directed mutagenesis identify several autophosphorylated residues required for the activity of PrkC, a Ser/Thr kinase from Bacillus subtilis

We have shown recently that PrkC, which is involved in developmental processes in Bacillus subtilis, is a Ser/Thr kinase with features of the receptor kinase family of eukaryotic Hanks kinases. In this study, we expressed and purified from Escherichia coli the cytoplasmic domain of PrkC containing the kinase and a short juxtamembrane region. This fragment, which we designate PrkCc, undergoes autop

Molecular and microstructural inventory of an isolated fossil bird feather from the Eocene Fur Formation of Denmark

An isolated, yet virtually intact contour feather(FUM-1980) from the lower Eocene Fur Formation of Denmarkwas analysed using multiple imaging and moleculartechniques, including field emission gun scanning electronmicroscopy (FEG-SEM), X-ray absorption spectroscopy andtime-of-flight secondary ion mass spectrometry (ToF-SIMS).Additionally, synchrotron radiation X-ray tomographicmicroscopy (SRXTM) waAn isolated, yet virtually intact contour feather (FUM-1980) from the lower Eocene Fur Formation of Denmark was analysed using multiple imaging and molecular techniques, including field emission gun scanning electron microscopy (FEG-SEM), X-ray absorption spectroscopy and time-of-flight secondary ion mass spectrometry (ToF-SIMS). Additionally, synchrotron radiation X-ray tomographic microscopy (SR

Using a modified 3D-printer for mapping the magnetic field of RF coils designed for fetal and neonatal imaging

An experimental setup for characterizing the magnetic field of MRI RF coils was proposed and tested. The setup consisted of a specially configured 3D-printer, a network analyzer and a mid-performance desktop PC. The setup was tested on a single loop RF coil, part of a phased array for fetal imaging. Then, the setup was used for determining the magnetic field characteristics of a high-pass birdcage

Methods to improve patient recruitment and retention in stroke trials

Background: The success of randomized-controlled stroke trials is dependent on the recruitment and retention of a sufficient number of patients, but fewer than half of all trials meet their target number of patients. Methods: We performed a search and review of the literature, and conducted a survey and workshop among 56 European stroke trialists, to identify barriers, suggest methods to improve r

Heat transfer and friction factor in a dimple-pin fin wedge duct with various dimple depth and converging angle

Purpose - The dimple is adopted into a pin fin wedge duct which is widely used in modern gas turbine vane cooling structure trailing edge region. The purpose of this paper is to study the effects of dimple depth and duct converging angle on the endwall heat transfer and friction factor in this pin fin wedge duct. Design/methodology/approach - The study is carried out by using the numerical simulat

A Flexible Link Function for Discrete-Time Duration Models

This paper proposes a discrete-time hazard regression approach based on the relation between hazard rate models and excess over threshold models, which are frequently encountered in extreme value modelling. The proposed duration model employs a flexible link function and incorporates the grouped-duration analogue of the well-known Cox proportional hazards model and the proportional odds model as s

Influence of Nuclear Structure on Decay Properties of Heavy Nuclei

This dissertation deals with the effects of nuclear structure on the α-decay properties, and on the fission-yielddistributions from the decay of heavy nuclei. The nuclear-structure and decay properties of superheavynuclei is one of the central topics for investigation. α decay is treated in a microscopic approach employingSkyrme-Hartree-Fock-Bogoliubov wave functions to describe the formation of aThis dissertation deals with the effects of nuclear structure on the α-decay properties, and on the fission-yielddistributions from the decay of heavy nuclei. The nuclear-structure and decay properties of superheavynuclei is one of the central topics for investigation. α decay is treated in a microscopic approach employingSkyrme-Hartree-Fock-Bogoliubov wave functions to describe the formation of a

Strukturomvandling och automatisering : Konsekvenser på regionala arbetsmarknader

Denna rapport handlar om den regionala ekonomiska strukturomvandling som ägt rum i Västra Götaland och Skåne sedan 1990-talet, och om den fortsatta automatiseringens framtida regionala avtryck på svenska lokala arbetsmarknader. Rapporten beskriver och gör en sammanfattning av den debatt som på senare år varit intensiv om automatiseringens framtida effekter på arbetsmarknaden. Med utgångspunkt i de

Regional ojämlikhet i Sverige : En historisk analys

De regionala klyftorna i Sverige har ökat sedan 1980-talet. Den här utvecklingen innebär politiska utmaningar. Stora regionala ojämlikheter hotar sammanhållningen i samhället och kan minska legitimiteten i det kommunala omfördelningssystemet. Skriften sätter in de senaste 30 årens ökande regionala skillnader i ett historiskt perspektiv. För detta ändamål presenteras nya dataserier på BNP per capit

Greening the Economy - Sustainable Cities : Course Guide

How can we shape our urban development towards sustainable and prosperous futures? This course explores sustainable cities as engines for greening the economy in Europe and around the world. We place cities in the context of sustainable urban transformation and climate change. We connect the key trends of urbanization, decarbonisation and sustainability. We examine how visions, experiments and inn

Local Government Cooperation : A Better Way to Respond to Conditions?

Studies have shown that all Swedish municipalities are involved in cooperation with other municipalities, and most frequent in soft forms like agreements. Often each municipality have full control of its activities and then join forces with others on the margin. However, in this chapter it is showed that this situation is undergoing a change. Municipalities facing new a new landscape are looking f

Kinetic and Computational Study of Dissociative Substitution and Phosphine Exchange at Tetrahedrally Distorted cis-[Pt(SiMePh2)2(PMe2Ph)2]

The substitution kinetics of Me2PhP in cis-Pt(SiMePh2)2(PMe2Ph)2 (1) by the chelating ligand bis(diphenylphosphino)ethane has been followed at 25.0 °C in dichloromethane by stopped-flow spectrophotometry. Addition of the leaving ligand causes mass-law retardation compatible with a dissociative process via a three-coordinate transition state or intermediate. Exchange of Me2PhP in 1 has been studied

Markis Lagergren och katolicismen i Sverige I

Markis Claes Lagergren är en av den nyare svenska katolska kyrkohistoriens kanske märkligaste konvertiter. Han har i memoarverket "Mitt livs minnen" från 1920-talet skildrat sin konversion och sitt liv fram till 35-årsåldern, alltså perioden 1853 till 1887. Memoarerna bygger på hans dagboksanteckningar, vilka för den följande perioden utgivits i urval och som i original finns i hans samling på Nor