Background: Despite significant symptomatic overlap between behavioral variant frontotemporal dementia (bvFTD) and primary psychiatric disorders (PPDs), a potential overlap in their structural anatomical changes has not been studied systematically. Methods: In this magnetic resonance imaging-based meta-analysis, we included studies on bvFTD, schizophrenia, bipolar disorder, and autism spectrum dis

Acrolein, as one of the most hazardous aldehydes, can be formed among the carbonyls from the combustion of bio-fuels or mixtures of bio- and conventional fuels. Moreover, acrolein is also an important combustion intermediate in the oxidations of higher unsaturated hydrocarbons. A deep understanding of acrolein combustion chemistry will be useful for the kinetic modeling of higher hydrocarbons and

Along with the ever-expanding interest in brands, the brand orientation concept has since its inception in the early 1990s steadily received more and more attention from scholars and practitioners alike. Brand orientation ultimately captures how organisations can develop sustainable competitive advantages in the form of brands. However, the conditions for brand management have dramatically changedAlong with the ever-expanding interest in brands, the brand orientation concept has since its inception in the early 1990s steadily received more and more attention from scholars and practitioners alike. Brand orientation ultimately captures how organisations can develop sustainable competitive advantages in the form of brands. However, the conditions for brand management have dramatically changed

Motivated by a need to characterize transient behaviors in large network systems in terms of relevant signal norms and worst-case input scenarios, we propose a novel approach based on existing theory for matrix pseudospectra. We extend pseudospectral theorems, pertaining to matrix exponentials, to an input-output setting, where matrix exponentials are pre- and post-multiplied by input and output m

Many long-term childhood cancer survivors suffer from treatment-related late effects, which may occur in any organ and include a wide spectrum of conditions. Long-term follow-up (LTFU) is recommended to facilitate early diagnosis and to ensure better health outcomes. Due to the heterogeneity of these sequelae, different specialists work together in the diagnosis and treatment of these conditions.

The role of mutations have been subject to many controversies since the formation of the Modern Synthesis of evolution in the early 1940ties. Geneticists in the early half of the twentieth century tended to view mutations as a limiting factor in evolutionary change. In contrast, natural selection was largely viewed as a “sieve” whose main role was to sort out the unfit but which could not create a

Neural network training and validation rely on the availability of large high-quality datasets. However, in many cases only incomplete datasets are available, particularly in health care applications, where each patient typically undergoes different clinical procedures or can drop out of a study. Since the data to train the neural networks need to be complete, most studies discard the incomplete d

Due to the migration megatrend, efficient and effective second-language acquisition is vital. One proposed solution involves AI-enabled conversational agents for person-centered interactive language practice. We present results from ongoing action research targeting quality assurance of proprietary generative dialog models trained for virtual job interviews. The action team elicited a set of 38 re

Background: Food access is an important aspect of health promotion for the elderly. The aim of this study was to investigate the relationship between distance to the nearest food store and diet variety in rural community-dwelling elderly Japanese. Methods: This cross-sectional study analyzed data from 1,103 elderly participants surveyed by mail in rural areas of Japan. Diversity of food intake was

Aims/hypothesis: Diabetic kidney disease (DKD) is the leading cause of kidney failure and has a substantial genetic component. Our aim was to identify novel genetic factors and genes contributing to DKD by performing meta-analysis of previous genome-wide association studies (GWAS) on DKD and by integrating the results with renal transcriptomics datasets. Methods: We performed GWAS meta-analyses us

BACKGROUND Ibrutinib, a Bruton's tyrosine kinase inhibitor, may have clinical benefit when administered in combination with bendamustine and rituximab and followed by rituximab maintenance therapy in older patients with untreated mantle-cell lymphoma. METHODS We randomly assigned patients 65 years of age or older to receive ibrutinib (560 mg, administered orally once daily until disease progressio

Verksamhet, människa och omvärld är den första boken på svenska om den kulturhistoriska verksamhetsteorin för de som arbetar med människor i social utsatthet. Centralt i teorin är att koppla ihop människan och hennes omvärld med begreppet verksamhet. Därigenom framkommer nya teoretiska perspektiv samt en helhetssyn på sociala problem som våld, gäng, sexuella övergrepp, missbruk, kriminalitet, mobb

We present the direct stabilization of the CEP of a high-repetition rate OPCPA by employing a Stereo-ATI pulsemeter for single-shot detection and feedback to the oscillator at the full OPCPA repetition rate.

Two-dimensional (2D) perovskites have emerged as promising building blocks for optoelectronic applications. To fabricate high-performance devices, the relation between the material structures and their function in terms of excited state and charge carrier dynamics need to be well understood. In this thesis, we investigate photophysics of 2D lead halide perovskite with different compositions to rev

The race to publish results during the outbreak of the new coronavirus (SARS-CoV-2) has highlighted the relevance of sharing data and research results more quickly and openly than the current scientific communication system, as well as the role of social media in this context. This paper aims to analyze the impact of open access on the production and dissemination of knowledge about COVID-19 in tr

Futures studies have shown an accelerated growth since the post-World War II period, in which governments and private companies have been attentive to the importance of "forecasting" new trends, mainly technological ones, for their security as an institution. Such studies have gained a new panorama from the proliferation of data on massive scales and the increasing processing capacity, leading to