The Emerging Pathogen Non-typeable Haemophilus influenzae : Roles of EF-Tu and P5 in Host-pathogen Interactions
Non-typeable Haemophilus influenzae (NTHi) is an emerging respiratory pathogen that causes a significant disease burden worldwide, yet an effective vaccine is still lacking. The focus of this thesis is to elucidate the critical molecular interactions governing NTHi pathogenesis and host immunity. We identified Elongation Factor Tu (EF-Tu) as a surface-exposed protein on NTHi, demonstrating its imm