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Inflammation and ischemia are common causes of perinatal brain damage. Ventilation with pure oxygen has previously been the prime choice during resuscitation following fetal asphyxia. In an in vivo sheep model incorporating the transition from fetal to neonatal life we demonstrate that hyperoxic resuscitation increases cerebral inflammatory activation which may aggravate subsequent injury. Inflam

Upconverting nanoparticles have recently drawn increasingly attention as contrast agents for optical bioimaging. They enable autofluorescence-free imaging within the tissue optical window, and improved spatial resolution as compared to conventional fluorescence-based contrast agents. (C) 2012 Optical Society of America

Artikeln behandlar 1900-talets meningskris såsom den återspeglas i Emmanuel Levinas och Hans Jonas tänkande.

This article presents a survey of techniques for ranking results in search engines, with emphasis on link-based ranking methods and the PageRank algorithm. The problem of selecting, in relation to a user search query, the most relevant documents from an unstructured source such as the WWW is discussed in detail. The need for extending classical information retrieval techniques such as boolean sear

Popular Abstract in Swedish Kardiovaskulär sjukdom är ett samlingsnamn för sjukdomar som involverar hjärtat och/eller kärlen. De är orsaken till 41 % av alla dödsfall i Sverige, och 12 % av alla svenskar lider av följderna av dessa sjukdomar. Ateroskleros, som är en kardiovaskulär sjukdom, kan upptäckas redan hos barn. Då ser man ateroskleros som en förändring i kärlväggen (plack) och i detta stadAtherosclerosis is triggered by LDL entrapment in the vessel wall. Oxidation and enzymatic processing of LDL give rise to inflammatory mediators such as lyso-PC. These inflammatory mediators attract monocytes into the vessel wall where they differentiate into macrophages. The macrophages adopt different phenotypes depending on the environment. In vitro, ex vivo, and in vivo studies were combined

Qualitative measurements of both OH and polycyclic aromatic hydrocarbons (PAH) as well as quantitative data of soot volume fraction f(v) have been obtained in vaporized liquid fuels, with the main goal of providing experimental data for combustion models and numerical mechanism validation. Measurements were carried out in a laminar coflow burner which was designed, built and integrated with an eva

A common application of nanometer-sized gold particles is as seed particles for growth of semiconductor nanowires, which are believed to act as highly promising building blocks in future electronic devices. In a majority of the reports of successful nanowire growth, gold has been the seed particle material of choice. In this review article we identify the different types of gold particles used to

The major histocompatibility class I (MHC-I) genes are highly polymorphic and the proteins that they encode play a crucial role in both the innate and the adaptive immune response. A MHC-I molecule consists of three parts, one polymorphic heavy chain, one invariant light chain, β2-microglobulin and a peptide of usually between 8-11 amino acids in length. The maturation and quality control of MHC-I

Flow injection analysis provides a convenient platform for the use of biosensors in the monitoring of bio-processes. A major requirement in bioprocess monitoring is real time information about various process parameters like concentration of products and substrates, flow rates, and injection volumes. Depending on the application, the monitoring requirements vary and this results in a need for diff

This article is concerned with the linkages between events occurring at the macro-level and psychological phenomena. In particular it seeks to elaborate on the possible effects of globalization, migration, and multiculturalism on groups' and individuals' subjective experiences of security. Special attention is given to the concept of dialogicality in the light of the challenges posed by an increas

Background: The Freezing of Gait Questionnaire (FOGQ) was developed in response to the difficulties of observing and quantifying freezing of gait (FOG) clinically as well as in laboratory settings. However, as the FOGQ is a clinician-administered patient-reported rating scale it cannot be used in postal surveys. Here we report the development and measurement properties of a self-administered versi

There is a paucity of studies assessing changes in measures of human neurotransmission during stressful events, such as surgery. Thirty-five patients without any neurological disorders undergoing knee replacements with spinal bupivacaine anaesthesia and propofol sedation had cerebrospinal fluid (CSF) drawn from a spinal catheter before, three hours after and the morning after surgery. The CSF conc

Background: Cancer of unknown primary (CUP) is a fatal cancer, accounting for 3-5% of all diagnosed cancers. Finding the primary site is important for therapeutic choices and we believe that the organ which is designated as the cause of death may give clues about the primary site. Methods: A total of 20,570 patients with CUP were identified from the Swedish Family-Cancer Database. Causes of death

Modelling of the ultrafiltration process is crucial for effective optimization of full-scale modules, and considerable effort has been devoted to describing the permeate flux during ultrafiltration. Many models use a detailed description of the mass transport and are thus valuable for the understanding of the fundamental mechanisms of ultrafiltration. However, for the prediction of the flux in mul

ALICE (A Large Ion Collider Experiment) is studying the physics of strongly interacting matter, and in particular the properties of the Quark–Gluon Plasma (QGP), using proton–proton, proton–nucleus and nucleus–nucleus collisions at the CERN LHC (Large Hadron Collider). The ALICE Collaboration is preparing a major upgrade of the experimental apparatus, planned for installation in the second long LH

A search for a heavy, CP-odd Higgs boson, A, decaying into a Z boson and a 125 GeV Higgs boson, h, with the ATLAS detector at the LHC is presented. The search uses proton-proton collision data at a centre-of-mass energy of 8 TeV corresponding to an integrated luminosity of 20.3 fb(-1). Decays of CP-even h bosons to tau tau or bb pairs with the Z boson decaying to electron or muon pairs are conside

The critical shortage of surgeons in many low- and middle-income countries (LMICs) prevents adequate responses to surgical needs, but the factors that affect surgeon migration have remained incompletely understood. The goal of this study was to examine the importance of personal, professional, and infrastructural factors on surgeon migration from LMICs to the United States. We hypothesized that th

The Zumaya section, northern Spain, is a suitable candidate to define the Global Stratotype Section and Point for the base of the Selandian Stage (Palaeocene) because of its excellent accessibility, exposure and stratigraphic continuity. Uncertainties exist, however, with regard to the stratigraphic horizon where to place the Danian/Selandian (D/S) boundary. Five potential stratigraphic horizons (

The majority of human embryonic stem cell lines depend on a feeder cell layer for continuous growth in vitro, so that they can remain in an undifferentiated state. Limited knowledge is available concerning the molecular mechanisms that underlie the capacity of feeder cells to support both the proliferation and pluripotency of these cells. Importantly, feeder cells generally lose their capacity to