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AIMS: To develop a sensitive mutation screening procedure suitable for routine analysis of the peripherin/RDS gene, and to estimate the nature and prevalence of peripherin/RDS gene mutations in Swedish patients with autosomal dominant retinitis pigmentosa. METHODS: To make the method as sensitive as possible, as many as eight segments, covering the three exons and the flanking intron sequences of
Biosensors based on whole bacterial cells and on bacterial heavy metal binding protein were used to determine the mercury concentration in soil. The soil samples were collected in a vegetable garden accidentally contaminated with elemental mercury 25 years earlier. Bioavailable mercury was measured using different sensors: a protein-based biosensor, a whole bacterial cell based biosensor, and a pl
Bostaden används mer och mer till att nyttja olika former av media, både individuellt och i grupp. Både stationär och bärbar hemelektronik har stor betydelse för hur vi möblerar och utnyttjar bostadens rum. Det gör att generellt utformade rum och flexibla rumssamband kommer att visa sig allt viktigare. Tekniken bidrar också till att det privata blir offentligt och det offentliga privat.
Background: Mutations in the PRSS1 gene explain most occurrences of hereditary pancreatitis (HP) but many HP families have no PRSS1 mutation. Recently, an association between the mutation N34S in the pancreatic secretary trypsin inhibitor (SPINK1 or PSTI) gene and idiopathic chronic pancreatitis (ICP) was reported. It is unclear whether the N34S mutation is a cause of pancreatitis per se, whether
Hittills har rättssociologi nästan uteslutande studerat rättens funktioner, utveckling och förändring inom dem samhälleliga ramar som inrättats i enlighet med den traditionella nationalstatens grundprinciper. Under de senare decennierna har det emellertid vuxit fram en omfattande metanationell verksamhet med sin egen utvecklingsmekanism och rationalitet, som i sitt verkningssätt tycks vara oberoen
Genetic engineering has been used to construct fusion proteins of Fusarium solani pisi cutinase and tryptophan-based tags, expressed in Saccharomyces cerevisiae, to increase the partitioning in aqueous two-phase systems. The separation systems were composed of thermoseparating polymers (random copolymers of ethylene oxide and propylene oxide, EOPO) and detergents (C12EOn). In this study, the fluor
This thesis concerns numerical calculations of compressible separated flows, with and without shocks, around wing sections using Large Eddy Simulations (LES). The considered geometries are the NACA 0012 wing section and the ONERA AT15A wing section. Compressible separated flows around wing sections are of considerable interest, for engineering and scientific reasons, since they involve transition,
We take our own life stories as points of departure to look at some of the ways in which women were politicized in Argentina and West Germany (our respective countries of origin), focusing on similarities as well as differences in our politicization processes. We aim at putting present discussions about global political movements into a historical perspective. We want also to illuminate the centra
A model of how to calculate the load distribution for a chain drive is presented. In the model the complete standard geometry is used without any assumptions. The rollers which are in contact with the sprockets can move freely along the tooth flanks and their positions are given be force equilibrium. Since the positions of the rollers and thereby also the load distribution are dependent on the two
Measurements are presented of inclusive charm and beauty cross sections in e(+)p collisions at HERA for values of photon virtuality Q(2) > 150 GeV2 and of inelasticity 0.1 < y < 0.7. The charm and beauty fractions are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured by the H1 vertex detector. The data are divided into fo
The burdens of childhood eczema are many and some can be assessed with quality of life (QoL) questionnaires. Seventy-eight Swedish children with mild-to-severe eczema ("atopic dermatitis", prurigo Besnier), fulfilling established diagnostic criteria, were investigated for the effect of eczema on QoL. This was measured with validated questionnaires: the Infants' Dermatitis Quality of Life Index (ID
Popular Abstract in Swedish Wellpapp är ett populärt material i förpackningar för transport och lagring av konsumentvaror. Den viktigaste anledningen till dess popularitet är materialets höga styvhet och styrka, i förhållande till vikt och kostnad. Ingenjörsmässig användning av wellpapp kompliceras av många faktorer. En väsentlig nackdel är materialets känslighet för fuktpåverkan, vilken dessutom The storage of compressive loaded boxes in an environment with naturally varying humidity is a practical issue in corrugated board employment. Time dependent variables such as moisture content, strain fields, stress fields and material strength play important roles for the time to failure. Supplementary, the stochastic nature of material and moisture load is obstructing the prediction of a reliabl
The article aims at pointing out the limitations of those archaeological approaches in the field of medieval studies that strictly follow the medieval social theory of the three and later four orders/estates. As an example of the possibilities offered by the use of an contextual approach in attempting to transcend the borders of the four-estate model, an analysis and interpretation of the pottery
Att prioritera betyder enligt Svenska Akademins ordlista att ge försteg eller förtur. Inom alla offentliga verksamheter råder resursbrist. Verksamheter präglas av prioriteringar mellan individer eller grupper av individer. För hälso- och sjukvårdens del har genom lag fastställts att den som har det största behovet också skall ges företräde till vård. Prioritering mellan individer skall göras utifr
New observations on the luminescence Of In2S3 and europium-doped In2S3 nanoparticles show a green (5 10 nm) emission from In2S3 and In1.8Eu0.2S3 nanoparticles while a blue (425 nm) emission is observed from ln(1.6)Eu(0.4)S(3) nanoparticles. Both the blue and green emissions have large Stokes shifts of 62 and 110 nm, respectively. Excitation with longer-wavelength photons causes the blue emission t
Two flavones, 4',5,7-trihydroxy-6-methoxy flavone (dinatin) and 4',5-dihydroxy-6, 7-dimethoxy flavone (skrofulein), were extracted from Artemisia herba alba L. Dinatin and skrofulein inhibited the binding of [methyl-3H]diazepam to rat brain membranes in vitro with IC50 of 1.3 and 23 mumol.L-1, respectively. The GABA-ratios (the ratio of IC50 values in the absence/presence of GABA in the binding as
