Observational epidemiology has made outstanding contributions to the discovery and elucidation of relations between lifestyle factors and common complex diseases such as type 2 diabetes. Recent major advances in the understanding of the human genetics of this disease have inspired studies that seek to determine whether the risk conveyed by bona fide risk loci might be modified by lifestyle factors

A new glacial geomorphological map of the Eyjabakkajokull forefield in Iceland is presented. The map covers c. 60 km(2) and is based on high-resolution aerial photographs recorded in August 2008 as well as field checking. Landforms are manually registered in a geographical information system (ArcGIS) based on inspection of orthorectified imagery and digital elevation models of the area. We mapped

Six strains isolated from fermented food were by 16S rDNA sequencing identified as Weissella species, clustering with the species-pair W. confusa/ W. cibaria. The strains were analysed for growth on glucose, xylose and xylooligosaccharides (XOS). All strains were xylose positive using the API CHL 50 test. Growth on XOS was observed for strain 85, 92, 145 and AV1, firstly by optical density measure

A methodology for evaluation of natural draft cooling tower (CT) performance and its application is presented. The study establishes the connection between CT performance and power output. It can estimate a change in a CT’s efficiency as well as an increase in power output as a function of cooling water temperature and load to the plant. The methodology consists of three subparts, i.e. Cooling Tow

The development and establishment of a Swedish translation of the Scale of Ethnocultural Empathy (SEE) was investigated in a sample of 788 participants. The SEE is a self-report instrument and is used to measure empathy directed toward people from ethnic cultural groups who are different from the respondent’s own ethnocultural group. Principal components factor analyses and confirmatory factor ana

The Archean Fiskenaesset Complex, SW Greenland, consists of an association of ca. 550-meter-thick layered anorthosite, leucogabbro, gabbro, and ultramafic rocks (peridotite, pyroxenite, dunite, hornblendite). The complex was intruded by tonalite, trondhjemite, and granodiorite (TTG) sheets (now orthogneisses) during thrusting that was followed by several phases of isoclinal folding. The trace elem

Charged-pion-interferometry measurements were made with respect to the second- and third-order event plane for Au+Au collisions at sqrt[s_{NN}]=200 GeV. A strong azimuthal-angle dependence of the extracted Gaussian-source radii was observed with respect to both the second- and third-order event planes. The results for the second-order dependence indicate that the initial eccentricity is reduced du

Objective A pay-for-performance (P4P) programme for primary care was introduced in 2011 by a Swedish county (with 1.6 million inhabitants). Effects on register entry practice and comparability of data for patients with diabetes mellitus were assessed. Design and setting Observational study analysing short-term outcomes before and after introduction of a P4P programme in the study county as compare

To investigate and describe the content, dissemination and effects of case management interventions for informal caregivers of older adults, focusing on outcomes related to patients' activities of daily living, nutrition assessment, pain measurement, depression, length of stay and to caregivers' satisfaction and difficulties.

We examined the association between perceived environmental barriers to outdoor mobility and loneliness among community-dwelling older people. In addition, we studied whether walking difficulties and autonomy in participation outdoors affected this association.

The focus of operations planning and control for manufacturing firms has expanded successively over the last 50 years. New principles, techniques, and systems have emerged that have allowed for new approaches. The perspective for planning and control has expanded from internal production operations to supply chain operations linking suppliers, manufacturers, and customers. In this paper, we take a

Objective. We evaluated in a proof-of-concept double-blind placebo-controlled randomized trial the efficacy and safety of intra-articular sprifermin (recombinant human fibroblast growth factor 18) in patients with symptomatic knee OA. Methods. Sprifermin was evaluated as intra-articular injection at 10, 30, and 100μg. Primary efficacy endpoint was change in central medial femorotibial compartment

In 2012 we celebrate the 125th anniversary of the unique molecule Troger's base (TB), first synthesized by Julius Troger in 1887. Being a V-shaped C2-symmetric chiral molecule, it possesses many interesting features. The TB field was reopened in 1985, when Craig S. Wilcox published the first crystallographic study of TB and described the synthesis and potential applications of TB analogues in supr

Traumatic brain injury (TBI) is one of the leading causes of death in children worldwide. Emerging evidence suggests that alterations in mitochondrial function are critical components of secondary injury cascade initiated by TBI that propogates neurodegeneration and limits neuroregeneration. Unfortunately, there is very little known about the cerebral mitochondrial bioenergetic response from the i

There are conflicting reports as to whether malignant peripheral nerve sheath tumor (MPNST) patients with neurofibromatosis type 1 (NF1) have worse prognosis than non-NF1 MPNST patients. Large clinical studies to address this problem are lacking due to the rareness of MPNST. We have performed meta-analyses testing the effect of NF1 status on MPNST survival based on publications from the last 50 ye

Background. Although there are putative mechanistic links between obesity and autoimmune diseases, obesity is not considered a risk factor for most autoimmune diseases. Methods. Using the nation-wide Hospital Discharge Register we defined a cohort of 29,665 patients hospitalized for obesity since year 1964. The patients were followed for hospitalization for any of 34 autoimmune or related conditio

The polychaete annelid Kingnites diamondi, a new paulinitid genus and species, is described from the Silurian of Baltoscandia. Its large maxillae differ morphologically from those of all other known paulinitids, particularly in being very elongate and having conspicuous myocoele openings and posterior portions of the first maxillae (MI). Albeit rare, this polychaete taxon is highly characteristic

Glial cell-line derived neurotrophic factor (GDNF) has demonstrated robust effects on dopamine (DA) neuron function and survival. A post-translational processing model of the human GDNF proprotein theorizes the formation of smaller, amidated peptide(s) from the proregion that exhibit neurobiological function, including an 11-amino-acid peptide named dopamine neuron stimulating peptide-11 (DNSP-11)