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Popular Abstract in Swedish Populärvetenskaplig sammanfattning på svenska Denna avhandling handlar om kalretikulin (engelska: calreticulin; CRT), ett protein som bidrar till att andra protein får rätt struktur och som också är inblandat i en kvalitetskontroll av dessa. CRT ser också till att kalciumbalansen i cellen upprätthålls. Hur går detta då till och hur bidrar denna avhandling till att öka kCalreticulin (CRT) is an endoplasmic reticulum (ER)-located protein involved in quality control of newly synthesized proteins as well as in calcium homeostasis of the cell. Most of what is known about CRT arises from studies of mammalian systems. However, using a Arabidopsis thaliana CRT gene expressed in mouse fibroblasts deficient of endogenous CRT, the wild type phenotype could be rescued with

Popular Abstract in Swedish Dykresponsen Andningsuppehåll (apné) eller fridykning ställer stora krav på att så effektivt som möjligt disponera de förråd med syrgas som finns i kroppen. Känsliga organ såsom hjärnan och hjärtat kan inte klara sig utan syrgas någon längre tid. Huden, musklerna och magtarm-kanalen har däremot en större tolerans mot syrgasbrist. Kroppens syrgasförråd finns framför allThis thesis deals with cardiovascular and respiratory effects of apneas in humans. During apnea (breath-holding), a number of interacting cardiovascular reflexes are initiated, and together these reflexes are called the “diving response”. The main cardiovascular characteristics of the human diving response are reduced heart rate, decreased cardiac output, peripheral vasoconstriction, and increased

Klimatet förändras, och det är människans aktiviteter som är orsaken. Utsläpp av växthusgaser från fossila bränslen och ohållbar markanvändning på global, regional och lokal nivå driver den pågående uppvärmningen. Hur dessa drivkrafter utvecklas framöver avgör hur stora klimatförändringarna blir på sikt. Därmed återfinns klimatproblematikens orsaker, men även dess lösningar, i hur vi bygger och ut

The traditional presentation about historical time-passing consists in a linear succession of facts in which some aspects of the life world evolve from others in an irreversible manner. The presentation of change is connected to the presentation of gradual or revolutionary linear changes that are irrevocable. I believe that this presentation could be considered correct for living organisms, but do

Eicosanoids are important for a wide range of physiological and pathophysiological processes.How their essential fatty acid precursors are absorbed and tissue distributed is not well charactherized. When given orally to rats, arachidonic acid (20:4) was retained in the small intestine to a larger extent than linoleic acid (18:2).More 20:4 than 18:2 was incorporated in phospholipids (PL) of the sma

In this paper, we examine the impact of instruction level parallelism (ILP) on the full H.264 video encoding application and give quantitative performance measures of a superscalar architecture. Most research efforts have concentrated on the data intensive parts, such as kernels but these are taking less time from the entire execution as encoders are using new, more efficient algorithms. This impo

This work stages a conversation between the French phenomenological philosopher Maurice Merleau-Ponty and philosophical theology, specifically as developed along an Augustinian trajectory. As the conversation unfolds, the outline of a new ontology is progressively sketched out – one that seeks to preserve the integrity of human beings as part of the natural world, as well as the integrity of the n

Abstract not available

The scope of this study is to compare John Philoponus and Cosmas Indicopleustes, two Christian individuals of different backgrounds and belonging to different fractions of the Church in the turbulent time for the Church in sixth century Alexandria. Any Christian is likely to feel the need to define how the tenets of his or her faith relate to contemporary science. As long as Christianity has exis