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BACKGROUND: Patients with kidney failure have a high risk for cardiovascular events. We aimed to evaluate the prognostic importance of selected biomarkers related to haemostasis, endothelial function, and vascular regulation in patients with acute coronary syndrome (ACS), and to study whether this association differed in patients with renal dysfunction.METHODS: Plasma was collected in 1370 ACS pat

PURPOSE: Acquired chemoresistance is a frequent event in small cell lung cancer (SCLC), one of the deadliest human malignancies. Histone deacetylase inhibitors (HDACi) have been shown to synergize with different chemotherapeutic agents including cisplatin. Accordingly, we aimed to investigate the dual targeting of HDAC inhibition and chemotherapy in SCLC.EXPERIMENTAL DESIGN: The efficacy of HDACi

Residual problems may occur from neuroma despite surgery. In a 12-month follow-up study using national register data, symptoms, and disabilities related to surgical methods and sex were evaluated in patients surgically treated for a neuroma. Among 196 identified patients (55% men; lower age; preoperative response rate 20%), neurolysis for nerve tethering/scar formation was the most used surgical m

Recent advances have shown that sound fields can be accurately interpolated between microphone measurements when the spatial covariance matrix is known. This matrix may be estimated in various ways; one promising approach is to use a plane wave formulation with sparse priors, although this may require the use of a many microphones to suppress the noise. To overcome this, we introduce a time domain

Background: The immunogenicity, safety, and efficacy of recombinant factor VIII (rFVIII) have gained increasing interest after the introduction of extended half-life products with various modifications of the rFVIII molecule, such as covalent attachment of polyethylene glycol (PEG). Anti-PEG antibodies may be associated with a temporary reduction of FVIII recovery, but according to previous studie

In this conceptual article, we argue that artificial intelligence (AI) systems are contributing to the generation of an environment of affordances for everyday information practices through which they exert influence on people and the planet in ways that often are left unrecognised. We illustrate our insights by focusing on the practices of information seeking in everyday life, suggesting that the

A method that could assess the whole vehicle non-exhaust particle (NEP) emission from the whole vehicle level was proposed by combining sealed housing with the chassis dynamometer. The intake and exhaust systems were connected to the out of the chamber to avoid possible effects on NEP emissions. The most distinguishing feature of the proposed method is the whole vehicle assessment of the NEP. Base

Segregated bimetallic nanoparticles like core-shell nanoparticles are of interest in various fields including biomedicine, catalysis, and optoelectronics. Aerosol technology is an optimal platform to control nanoparticle size, structure, and composition, which are some of the most important parameters tuning the material performance for the intended applications. Here, we develop a novel evaporato

Background: It has been reported that caseload midwifery, which implies continuity of midwifery care during pregnancy, childbirth, and the postnatal period, improves the outcomes for the mother and child. The aim of this study was to review benefits and risks of caseload midwifery, compared with standard care comparable to the Swedish setting where the same midwife usually provides antenatal care

Fibril-reinforced poroviscoelastic material models are considered state-of-the-art in modeling articular cartilage biomechanics. Yet, cartilage material parameters are often based on bovine tissue properties in computational knee joint models, although bovine properties are distinctly different from those of humans. Thus, we aimed to investigate how cartilage mechanical responses are affected in t

Background: Obstructive sleep apnea (OSA) is associated with atrial fibrillation (AF) in cardiac cohorts. Less is known regarding the magnitude of this association in a sleep clinic cohort with vs. without excessive daytime sleepiness (EDS). Objectives: To explore the association of OSA severity with AF in a sleep clinic cohort stratified by EDS. Patients and methods: All consecutive adults (n = 3

The reformation and characterisation of the passive film formed on ultra-thin 316 L after hydrogen charging is investigated by combining EBSD, TMDS, XRD, Synchrotron-based XPS, and electrochemical experiments. The results show that ultra-thin foil reforms a passive film after 12 h of hydrogen release in NaCl solution. The reformed passive film is half the thickness of the as-received passive film

Background and Objectives: Cancer biomarkers provide information on the characteristics and extent of cancer progression and help inform clinical decision-making. However, they can also play functional roles in oncogenesis, from enabling metastases and inducing angiogenesis to promoting resistance to chemotherapy. The resulting evolution could bias estimates of cancer progression and lead to subop

Gas-phase transmission electron microscopy is an essential tool for elucidating the mechanisms involved in the synthesis of functional materials. Here, we review the latest developments in understanding the growth of novel nanostructural materials afforded by following the process in situ in electron microscopes. Particular focus is on investigations of catalyzed growth of one-dimensional carbon-b

Okara is a by-product from the production of soy beverages, which has a high content of protein and fiber. Even though it has a high nutritional value, it is generally discarded or used as animal feed or compost. The problem is its short shelf life due to its high water content and high water activity. The aim of this study was to investigate the effect of high-pressure pasteurization at 200 MPa,

In order to provide clinical utility for research of how art therapists perceive clients’ inner change, the authors created a structured observational framework. This note-taking and assessment consist of five themes and sub-themes: Therapeutic Alliance, Creating, Affect-Awareness, Self-Awareness, and Ego-Strength. The framework was designed to be clinically-friendly, adaptable to various settings

The issue of the short microbiological shelf life of residues from the plant-based beverage industry creates a large food waste problem. Today, the oat beverage residue, in this study referred to as oat okara, is generally converted to energy or used as animal feed. High-pressure pasteurization (200 MPa, 400 MPa, and 600 MPa) was applied to oat okara to investigate the effect on shelf life and mic

Enligt Hochschild (1983) kännetecknas emotionellt lönearbete av ett antal aspekter: institutionaliserade regler kring vad den arbetande får känna och hur de får visa det; reglerna förväntas följas av den arbetande (med hjälp av olika strategier); någon som säkerställer att reglerna följs – en ”emotional supervisor”; och att den arbetandes känslor har ett bytesvärde. I den här artikeln använder jag