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Cognitive behavioural therapy in multiple sclerosis: A randomized controlled pilot study of acceptance and commitment therapy.
OBJECTIVE: The aim of this study was to design a trial that could evaluate the effect of acceptance and commitment therapy as a group-intervention for multiple sclerosis patients with psychological distress. DESIGN: Randomized controlled trial with assessment at pretreatment, end of treatment, and at 3-month follow-up. SUBJECTS: Multiple sclerosis outpatients with elevated symptoms of anxiety and/
Low haemosporidian diversity and one key-host species in a bird malaria community on a mid-atlantic island (sao miguel, azores)
When host species colonize new areas, the parasite assemblage infecting the hosts might change, with some parasite species being lost and others newly acquired. These changes would likely lead to novel selective forces on both host and its parasites. We investigated the avian blood parasites in the passerine bird community on the mid-Atlantic island of Sao Miguel, Azores, a bird community originat
Human neural stem cells: region-specific properties and prospects for cell therapy
Popular Abstract in Swedish Stroke är en sjukdom som främst drabbar äldre och är den största anledningen till att människor får olika slags handikapp såsom förlamning och afasi. Det finns ännu ingen effektiv behandling för att lindra symtom och lidande efter en stroke, förutom rehabilitering, och därför kostar stroke samhället enormt mycket pengar. Befolkningen blir allt äldre, vilket även medför Cell replacement by neural transplantation can, in animal models of neurodegenerative diseases, reconstruct damaged brain circuitry. In the clinical situation, the graft material used for cell therapy must, most likely, be of human origin. The human fetal brain is one potential source of neural stem cells (NSCs) for cell replacement therapy in neurodegenerative disorders such as stroke. Stroke is
MetCap: a bioinformatics probe design pipeline for large-scale targeted metagenomics
Background: Massive sequencing of genes from different environments has evolved metagenomics as central to enhancing the understanding of the wide diversity of micro-organisms and their roles in driving ecological processes. Reduced cost and high throughput sequencing has made large-scale projects achievable to a wider group of researchers, though complete metagenome sequencing is still a daunting
Passive as an indicator of alignment change in terms of transitivity
Struggling to survive for the sake of the unborn baby: a grounded theory model of exposure to intimate partner violence during pregnancy
Background: Intimate partner violence (IPV) during pregnancy is a serious matter which threatens maternal and fetal health. The aim of this study was to develop a grounded theoretical model of women's experience of IPV during pregnancy and how they handle their situation. Method: Ten interviews with women who had experience of being exposed to IPV during pregnancy were analyzed using the grounded
Elevated Serum GAD65 and GAD65-GADA Immune Complexes in Stiff Person Syndrome.
Glutamic acid decarboxylase 65 (GAD65) and autoantibodies specific for GAD65 (GADA) are associated with autoimmune diseases including Stiff Person Syndrome (SPS) and Type 1 diabetes (T1D). GADA is recognized as a biomarker of value for clinical diagnosis and prognostication in these diseases. Nonetheless, it remains medically interesting to develop sensitive and specific assays to detect GAD65 pre
Human complement activation by smooth and rough Proteus mirabilis lipopolysaccharides
Proteus mirabilis bacilli play an important role in human urinary tract infections, bacteremia, and rheumatoid arthritis. The authors previously studied human complement C3 conversion by smooth-form P. mirabilis O10, O23, O30, and O43 lipopolysaccharides (LPSs) and showed that smooth Proteus LPSs fragmented C3 in a dose- and time-dependent manner. In the present study, one smooth P. mirabilis S195
Swirl sign in intracerebral haemorrhage: definition, prevalence, reliability and prognostic value
Background: Swirl sign has previously been described in epidural hematomas as areas of low attenuation, radiolucency or irregular density. The aims of this study were to describe swirl sign in ICH, study its prevalence, study the reliability of the subjective evaluation on computed tomography (CT), and to explore its prognostic value. Methods: CTs of 203 patients with ICH were retrospectively eval
Arkeologi och identitet
In this book several authors from the Nordic countries discuss the concept of identity as used within archaeology. Identity is as well part of the cultural heritage as an active component in today's political discussion. Ranging from present uses of identity today to the use of identity in the past, the 17 articles in the book show how identity works within archaeology.
Signatures of Wigner localization in epitaxially grown nanowires
It was predicted by Wigner in 1934 that an electron gas will undergo a transition to a crystallized state when its density is very low. Whereas significant progress has been made toward the detection of electronic Wigner states, their clear and direct experimental verification still remains a challenge. Here we address signatures of Wigner molecule formation in the transport properties of InSb nan
General-purpose event generators for LHC physics
We review the physics basis, main features and use of general-purpose Monte Carlo event generators for the simulation of proton-proton collisions at the Large Hadron Collider. Topics included are: the generation of hard scattering matrix elements for processes of interest, at both leading and next-to-leading QCD perturbative order; their matching to approximate treatments of higher orders based on
Laser pulse propagation and enhanced energy coupling to fast electrons in dense plasma gradients
Laser energy absorption to fast electrons during the interaction of an ultra-intense (10(20) Wcm(-2)), picosecond laser pulse with a solid is investigated, experimentally and numerically, as a function of the plasma density scale length at the irradiated surface. It is shown that there is an optimum density gradient for efficient energy coupling to electrons and that this arises due to strong self
Safety and efficacy of drug-eluting vs. bare metal stents in patients with diabetes mellitus: long-term follow-up in the Swedish Coronary Angiography and Angioplasty Registry (SCAAR)
Patients with diabetes mellitus have more extensive coronary artery disease, more disease progression, and restenosis. The use of drug-eluting stents (DES) in these patients is widespread, despite uncertain long-term safety and efficacy. All consecutive patients with diabetes mellitus in Sweden who underwent percutaneous coronary intervention were entered into the Swedish Coronary Angiography and
Frequency-dependent echolocation beam pattern of the bottlenose dolphin.
Moore and others (2008) previously showed that bottlenose dolphins are capable of beam steering and controlling the vertical and horizontal widths of the echolocation beam. A follow-on study was performed using the same methods as the previous study, but with a younger animal and a higher resolution diamond-shaped hydrophone array for characterizing the beam. The dolphin performed a target detecti
Two-dimensional elastic contact model for rubber covered rollers
A model for the contact between a rubber covered roller and a rigid roller was developed using analytical functions. The model, being two-dimensional, connects the line load, geometric properties (roller radii, rubber thickness) and the shear modulus of the rubber to nip properties in the roller contact. The output from the model is the indentation of the rigid roller into the rubber, the nip maxi
Three-dimensional ultrasound studies of normal and abnormal ovaries
Popular Abstract in Swedish Äggstockarna genomgår förändringar under en normal menstruationscykel. I samband med tumörväxt i äggstockarna utvecklas nya blodkärl. Dessa förändringar kan upptäckas med både tvådimensionellt (2D) och tredimensionellt (3D) gråskale- och Doppler-ultraljud. Med Doppler-ultraljud kan man upptäcka blodkärl och uppskatta blodflödeshastigheterna i blodkärlen. Referensvärden The aims of this work were: 1) to estimate the number of follicles, ovarian volume and power Doppler vascular indices and their changes with age using three-dimensional (3D) transvaginal grey-scale and power Doppler ultrasound in asymptomatic women of fertile age either with natural menstrual cycles or using combined oral contraceptives, and 2) to determine whether tumour vascularity, assessed by
Global transcriptional analysis of pheromone biosynthesis-related genes in the female turnip moth, Agrotis segetum (Noctuidae) using a custom-made cDNA microarray.
Using a custom-made cDNA microarray, global transcriptional analyses were conducted to identify genes differentially regulated in the pheromone gland as compared to the remaining insect tissue of the moth Agrotis segetum (Noctuidae). A two-fold or larger difference in relative expression levels was found for 227 of 864 genes investigated comparing the two tissues. Unexpectedly, an antennal binding
