Abstract L-DOPA-induced dyskinesia in Parkinson's Disease (PD) is associated with large increases in brain dopamine (DA) levels following drug dosing, but the precise significance of this phenomenon is not understood. Here we compare DA efflux and metabolism in the striatum and the substantia nigra (SN) in dyskinetic and non-dyskinetic animals following a standard dose of L-DOPA. Rats with 6-OHDA

AIM: The long-term effects of gastrectomy and various reconstructions of the gastrointestinal tract on fasting plasma levels of gastrointestinal hormones known to contribute to the control of gastrointestinal motor function were evaluated in pigs. MATERIALS AND METHODS: Domestic pigs were randomly selected to sham surgery or total gastrectomy (TG) followed by reconstruction with oesophago-jejunost

An evaluation of the four CFD software; CFX, FDS, SMAFS and SOFIE, have been performed. This report describes the final validation study.

BACKGROUND: Improved surgical techniques and oncological treatment render many advanced pelvic tumors amenable to curative resection. We evaluated morbidity, survival, and quality of life (QoL) after extended pelvic procedures. METHODS: From January 2003 to November 2008, 85 patients underwent multivisceral pelvic resection; 87% had colorectal or anal malignancies. Preoperatively, endoscopy and im

The pathophysiology behind gastrointestinal dysmotility in diabetes mellitus is unknown. Both esophageal dysmotility and gastroparesis have been shown to be associated with retinopathy, suggesting that microangiopathy is important in the common etiology. The aim of the present study was to examine whether patients with diabetes exhibit microangiopathy in the colon, and if present, to correlate mic

The FIPEC project is a research project funded by DG XII of the European Commission and co-financed by several European cable manufacturers, compounders, cable users and governmental research bodies. The FIPEC project has developed different levels of testing ranging from a small-scale, cone calorimeter test procedure developed for cables and materials, a full-scale test procedure based on the IEC

The extended mind debate is, to large extent, a debate over where and how to locate the boundary between cognitive mind and non-cognitive world. Concepts of “internal” and “external”, taken from the domain of physical volumes, are metaphorical, at best, applied to entities like mind. Strongly held intuitions betray metaphysical starting points that prejudice the debate. If one does not accept thes

Abstract OBJECTIVE: Anaemia is a common complication of renal failure. It can be treated with erythropoietin (EPO) administration, red blood cell transfusion (RBCT), or a combination of both. EPO has been registered for the treatment of renal anaemia in Sweden since the beginning of the 1990s, and is the primary treatment regimen for anaemia related to renal failure. The objective of this study wa

We consider the clustering structure of wireless MIMO channels, and the impact that multiple clusters have on the performance of MIMO systems. We show that multiple clusters frequently occur in urban environments. We then proceed to demonstrate that a channel with multiple scatterer clusters behaves differently than a channel with one cluster and the same rms angular spread. The differences are qu

STUDY DESIGN: Qualitative descriptive. INTRODUCTION: Cold sensitivity is a common and persistent complaint after hand injuries. PURPOSE OF THE STUDY: To explore the experiences of severe cold sensitivity, its consequences for daily life, and the strategies for enduring and enabling occupation. METHODS: Fifteen hand-injured patients with abnormal cold sensitivity were interviewed. The transcribed t

Low oxygen pressure (hypoxia) is a physiological condition that has been linked to tumor progression and increased malignancy in several cancer forms. Cells of the childhood neoplasm neuroblastoma respond to hypoxia by attaining a lower grade of differentiation, which clinically is associated with poor prognosis. Furthermore, expression of the hypoxia inducible factor-2alpha correlates to poor out