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Antinuclei found in cosmic rays could provide a smoking gun signal for dark matter as this signal is virtually background free. The study of 3He cosmic rays requires the knowledge of their production, propagation in the galaxy and annihilation cross-section. While the former two have been already estimated with data-driven methods, there were no experimental data available for the 3He inelastic cr
We measured a set of π±Σ∓, π0Σ0, and π−Σ0 invariant mass spectra below and above the K¯N mass threshold in K−-induced reactions on deuteron. The measured πΣ mass spectral shape is well reproduced via the two-step mechanism, i.e., a neutron knocked out at a forward angle from a deuteron by an incident K−, with the K¯ recoiled backward reacting with the residual nucleon to produce π and Σ. We deduce
Objective: Correct diagnosis of early rheumatoid arthritis (RA) is essential for optimal treatment choices. No pathognomonic test is available, and diagnosis is based on classification criteria, which can result in misdiagnosis. Here, we examined the differences between actual and misdiagnosed RA cases in a long-term cohort of patients included based on the ACR-1987 classification criteria. Method
The application of multiple omics technologies in biomedical cohorts has the potential to reveal patient-level disease characteristics and individualized response to treatment. However, the scale and heterogeneous nature of multi-modal data makes integration and inference a non-trivial task. We developed a deep-learning-based framework, multi-omics variational autoencoders (MOVE), to integrate suc
Background: The global community has committed to achieving universal access to sexual and reproductive health and rights (SRHR) services, but how to do it remains a challenge in many low-income countries. Capacity development is listed as a means of implementation for Agenda 2030. Although it has been a major element in international development cooperation, including SRHR, its effectiveness and
The Cherenkov Telescope Array (CTA) is a next generation ground-based very-high-energy gamma-ray observatory that will allow for observations in the >10 GeV range with unprecedented photon statistics and sensitivity. This will enable the investigation of the yet-marginally explored physics of short-time-scale transient events. CTA will thus become an invaluable instrument for the study of the phys
Tenosynovial giant cell tumour (TGCT) is a rare, locally aggressive, mesenchymal tumor arising from the joints, bursa and tendon sheaths. TGCT comprises a nodular- and a diffuse-type, with the former exhibiting mostly indolent course and the latter a locally aggressive behavior. Although usually not life-threatening, TGCT may cause chronic pain and adversely impact function and quality of life (Qo
In these proceedings we summarize the current status of the study of the sensitivity of the Cherenkov Telescope Array (CTA) to detect diffuse gamma-ray emission from the Perseus galaxy cluster. Gamma-ray emission is expected in galaxy clusters both from interactions of cosmic rays (CR) with the intra-cluster medium, or as a product of annihilation or decay of dark matter (DM) particles in case the
Laboratory and animal research support a protective role for vitamin D in breast carcinogenesis, but epidemiologic studies have been inconclusive. To examine comprehensively the relationship of circulating 25-hydroxyvitamin D [25(OH)D] to subsequent breast cancer incidence, we harmonized and pooled participant-level data from 10 U.S. and 7 European prospective cohorts. Included were 10,484 invasiv
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Structural changes and neuropathology in the hypothalamus have been suggested to contribute to the non-motor manifestations of Huntington's disease (HD), a neurodegenerative disorder caused by an expanded cytosine-adenine-guanine (CAG) repeat in the huntingtin (HTT) gene. In this study, we investigated whether hypothalamic HTT expression causes transcriptional changes. Hypothalamic RNA was isolate
The protochlorophyll(ide) present in primary roots of dark-grown corn (Zea mays) seedlings has an in vivo absorption maximum at 634 nm. Red light converts the pigment to chlorophyll(ide) a with an absorption maximum at 675 nm.
In acetonitrile, polyisoprene-b-poly(methyl methacrylate) (PI−PMMA) diblock copolymers form starlike micelles with a dense core of the insoluble PI blocks and a soft solvent-swollen corona of the soluble PMMA blocks. Static and dynamic light scattering experiments in combination with viscosity measurements show that these micelles behave hydrodynamically as hard spheres. The block copolymers are l
