Immunoinformatics study of procyanidins as mast cell stabilizers
Background: Allergens are foreign proteins that stimulate the production of immunoglobulin E (IgE), when they come in contact with human body. These allergens after binding with IgE through FcεRI receptor, triggers the signal transduction reaction in mast cell and basophil cells, leading to allergic reactions by releasing some mediators. Four correctly written as surface-exposed tryptpphans Trp 87