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Effects of various protective clothing and thermal environments on heat strain of unacclimated men: The PHS (predicted heat strain) model revisited

Five protective garments were assessed on eight unacclimated male subjects at two WBGT temperatures: 19.0 and 24.5 °C. The thermophysiological responses and subjective sensations were reported. The PHS model (ISO7933) was used for predicting thermophysiological responses for each testing scenario. It was found that there were significant differences between clothing FIRE and other clothing on ther

Swedish coastal herring fisheries in the wake of an ITQ system

The European common fisheries policy (CFP) advocates measures to sustain small-scale fisheries; hence, in the European Commission's proposal for a reformed CFP, these are exempted from a mandatory system with tradable fishing concessions. This opens up for management actions designed for small-scale fisheries, but also implies new management issues. This article provides insights into the topic ba

A performance analysis of porous graphite foam heat exchangers in vehicles

Due to the increasing cooling power and space limitation in vehicles, a new compact heat exchanger graphite foam heat exchanger is proposed for vehicle cooling application. The graphite foam has high thermal conductivity (the effective thermal conductivity is 40-150 W/m K) and low density (0.2-0.6 g/cm(3)), but it has high flow resistance which is a problem in heat exchanger applications. In order

Vulnerability analysis of interdependent critical infrastructures : case study of the Swedish railway system

Critical infrastructures provide essential services which enable our society to function. Disruptions in infrastructures can have widespread effects, not only for the originating infrastructure but also, through mutual dependencies, for other infrastructures. Identifying vulnerabilities inherent in these system-of-systems is thus highly critical for the proactive management and avoidance of future

Optimizing Ethanol and Methane Production from Steam-pretreated, Phosphoric Acid-impregnated Corn Stover.

Pretreatment is of vital importance in the production of ethanol and methane from agricultural residues. In this study, the effects of steam pretreatment with phosphoric acid on enzymatic hydrolysis (EH), simultaneous saccharification and fermentation (SSF), anaerobic digestion (AD) and the total energy output at three different temperatures were investigated. The effect of separating the solids f

Human Papillomavirus neutralizing and cross-reactive antibodies induced in HIV-positive subjects after vaccination with quadrivalent and bivalent HPV vaccines.

Ninety-one HIV-infected individuals (61 men and 30 women) were randomized to vaccination either with quadrivalent (Gardasil™) or bivalent (Cervarix™) HPV vaccine. Neutralizing and specific HPV-binding serum antibodies were measured at baseline and 12 months after the first vaccine dose. Presence of neutralizing and binding antibodies had good agreement (average Kappa for HPV types 6, 11, 16, 18, 3

Body temperature changes during simulated bacterial infection in a songbird: fever at night and hypothermia during the day

Although fever (a closely regulated increase in body temperature in response to infection) typically is beneficial, it is energetically costly and may induce detrimentally high body temperatures. This can increase the susceptibility to energetic bottlenecks and risks of overheating in some organisms. Accordingly, it could be particularly interesting to study fever in small birds, which have compar

Diffractive gauge bosons production beyond QCD factorization

We discuss single diffractive gauge boson d (gamma*, W+/-, Z) production in proton-proton collisions at different (Large Hadron Collider and Relativistic Heavy Ion Collider) energies within the color dipole approach. The calculations are performed for gauge bosons produced at forward rapidities. The diffractive cross section is predicted as a function of the fractional momentum and invariant mass

Quantifying the relative importance of lake emissions in the carbon budget of a subarctic catchment

Climate change and thawing of permafrost will likely result in increased decomposition of terrestrial organic carbon and subsequent carbon emissions to the atmosphere from terrestrial and aquatic systems. The quantitative importance of mineralization of terrestrial organic carbon in lakes in relation to terrestrial carbon fluxes is poorly understood and a serious drawback for the understanding of

Landscape heterogeneity and farming practice alter the species composition and taxonomic breadth of pollinator communities

Effects of landscape heterogeneity and farming practice on species composition are less well known than those on species richness, in spite of the fact that community composition can be at least as important for ecosystem services, such as pollination. Here, we assessed the effect of organic farming and landscape heterogeneity on pollinator communities, focusing on multivariate patterns in species

TECHNOLOGICAL ADVANCES IN HYBRID IMAGING AND IMPACT ON DOSE.

New imaging technologies utilising X-rays and radiopharmaceuticals have developed rapidly. Clinical application of computed tomography (CT) has revolutionised medical imaging and plays an enormous role in medical care. Due to technical improvements, spatial, contrast and temporal resolutions have continuously improved. In spite of significant reduction of CT doses during recent years, CT is still

Characteristics of short fatigue crack growth in the vicinity of a low angle grain boundary

The influence on the crack growth behaviour of a short edge crack under fatigue due to different configurations of a nearby located low angle grain boundary is investigated under quasi-static and plane strain conditions. The geometry is modelled by distributed dislocation dipole elements in a boundary element method approach, and the plasticity is described by discrete dislocations, located along

NURR1 in Parkinson disease-from pathogenesis to therapeutic potential.

In Parkinson disease (PD), affected midbrain dopamine (DA) neurons lose specific dopaminergic properties before the neurons die. How the phenotype of DA neurons is normally established and the ways in which pathology affects the maintenance of cell identity are, therefore, important considerations. Orphan nuclear receptor NURR1 (NURR1, also known as NR4A2) is involved in the differentiation of mid

The Establishment of FRONTEX: A New Institutionalist Approach

As border management continues to be a contentious and fast developing policy area in the EU, a better understanding of FRONTEX is needed. This article takes the new institutionalist approach that the functioning of institutions is dependent on the conditions under which they emerge. Drawing on documentary resources and semi-structured interviews with EU officials, the article traces the process l

A systematic review of risk factors associated with transitioning from regional musculoskeletal pain to chronic widespread pain

Chronic widespread pain has limited treatment options and is associated with pronounced negative individual and socioeconomic consequences. Patients with local or regional pain may be at a risk for developing chronic widespread pain. Knowledge of such risk factors can help prevent chronic widespread pain. This study systematically reviews the literature that examines risk factors associated with d

Laser spectroscopic gas concentration measurements in situations with unknown optical path length enabled by absorption line shape analysis

The concentrations of molecular oxygen and nitrogen in a gas mixture were determined by their impact on the shape of a water vapor line in the near infrared region using diode laser absorption spectroscopy. The shape of the water vapor line depends on the composition of other gases in the mixture and can therefore be used to deduce the concentration of partner molecules, e. g., oxygen, in the buff

Acoustofluidics 20: Applications in acoustic trapping.

This part of the Acoustofluidics tutorial series reviews applications in acoustic trapping of micron-sized particles and cells in microfluidic systems. Acoustic trapping enables non-invasive and non-contact immobilisation of cells and particles in microfluidic systems. Acoustic trapping has been used for reducing the time needed to create 3D cell clusters, enhance particle-based bioassays and faci

Nuclear expression of Glycogen synthase kinase-3 beta and lack of membranous beta-catenin is correlated with poor survival in colon cancer

Dysregulation of Wnt/beta-catenin signaling is a hallmark of colon cancer. Glycogen synthase kinase-3 beta (GSK-3 beta) can be a positive regulator of survival and proliferation of cultured colon cancer cell but its role in clinical colon cancer is unknown. Our objectives were to evaluate the role of GSK-3 beta in colon cancer. A tumor tissue microarray of primary colon cancers and metastases was

Low BRAF and NRAS expression levels are associated with clinical benefit from DTIC therapy and prognosis in metastatic melanoma

Metastatic melanoma is characterized by a poor response to chemotherapy. Furthermore, there is a lack of established predictive and prognostic markers. In this single institution study, we correlated mutation status and expression levels of BRAF and NRAS to dacarbazine (DTIC) treatment response as well as progression-free and overall survival in a cohort of 85 patients diagnosed with advanced mela

Sexual Knowledge in Patients With a Myocardial Infarction and Their Partners.

BACKGROUND:: Sexual health and sexual activity are important elements of an individual's well-being. For couples, this topic is often affected after a myocardial infarction (MI). It has become increasingly clear that, after an MI, patients are insufficiently educated on how to resume normal sexual activity. However, sufficient data on the general knowledge that patients and partners have about sex