Laser-induced Fluorescence Studies of Meso-tetra(hydroxyphenyl)chlorin In Malignant and Normal-tissues In Rats
meso-Tetra(hydroxyphenyl)chlorin (mTHPC) is an attractive second-generation dihydroporphyrin photosensitiser for use in photodynamic therapy. In this study, 1.3mgkg(-1) body weight mTHPC was administered intravenously, and laser-induced fluorescence was used to characterise and compare its localisation and retention in different rat tissues, including an induced experimental adenocarcinoma, 24 h a