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The main objective of this thesis was to gain further insight into the relationship between the exposed surfaces and the functional properties of antibodies and their complexes with antigens in solution. To study this relationship, a new technique, liquid-liquid partition chromatography (LLPC) in aqueous two-phase systems, was developed further with respect to sensitivity, selectivity and reproduc
This thesis concerns a highly efficient nanoparticle-based capillary electrochromatography separation technique and its coupling with mass spectrometric detection. From chromatographic theory, it is well known that the separation efficiency increases with decreasing particle size. However, as the particle size decreases, the pressure required to push a liquid through the column also increases. Thi
Many cells are mechanoregulated; their activities are performed at a rate partly determined by the biophysical stimulus acting on them. Computer simulations that would capture this could be used to predict the effect of physical exercise on tissue health. They could also be used to simulate how the tissues surrounding a medical device would respond to the placement of that device. Since cells are
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Abstract in Undetermined Astra- och Microsoft-fallen väntar på avgöranden i Förstainstansrätten. Bägge väcker viktiga principfrågor i skärningspunkten mellan immaterialrätt och konkurrensrätt. Astra1 har fällts av kommissionen för att företaget missbrukat sin dominerande ställning. Med tveksamma och delvis felaktiga uppgifter har Astras ”blockbuster” Losec fått ett förlängt patentskydd. Trots ins
In this article the mediatisation of Zlatan Ibrahimovic's autobiography, written by the journalist David Lagercrantz, is investigated through the reception of the book as well as of other media formats in which it was made public. A main point made is that the processes of mediatisation is a main factor in creating a literary trademark and bestseller. The footballer's mythic life story, as express
This Technical Design Report (TDR) for the High-level Trigger (HLT), Data Acquisition (DAQ) and Controls of the ATLAS experiment builds on the earlier documents published on these systems: Trigger Performance Status Report, DAQ, EF, LVL2 and DCS Technical Progress Report, and High-Level Triggers, DAQ and DCS Technical Proposal. Much background and preparatory work relevant to this TDR is reference
