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BACKGROUND: Monoclonal antibodies (mAbs) towards CGRP or the CGRP receptor show good prophylactic antimigraine efficacy. However, their site of action is still elusive. Due to lack of passage of mAbs across the blood-brain barrier the trigeminal system has been suggested a possible site of action because it lacks blood-brain barrier and hence is available to circulating molecules. The trigeminal g

The treatment of glaucoma is focused on reducing the intraocular pressure to a level at which progression is impeded. A diagnosis of glaucoma is not considered certain until progression is confirmed, and thus detecting progression is a central aspect in both the diagnosing and the monitoring of glaucoma patients. Progression can be identified either through examination of either functional changes

PURPOSE: There is a dearth of research on coping strategies of patients with malignant lymphoma. The aim of this article is to explore how these patients cope with cancer in everyday life.METHOD: Semi-structured interviews were conducted with nine patients in Sweden. A thematic analysis was made, inspired by Antonovsky’s theory of sense of coherence. The SRQR checklist was used. RESULTS: Patient’sPurposeThere is a dearth of research on coping strategies of patients with malignant lymphoma. The aim of this article is to explore how these patients cope with cancer in everyday life.MethodSemi-structured interviews were conducted with nine patients in Sweden. A thematic analysis was made, inspired by Antonovsky's theory of sense of coherence. The SRQR checklist was used.ResultsPatient's coping

Thrree poems by English poet Rachael Boast in translation to Swedish by Lars Gustaf Andersson

This article develops an analysis of Gender whereby D-gender entersgrammar as a feature variable (edge linker), without a fixed value,either probing n or scanning the context for a value. Only the latterstrategy is available in pronominal gender languages such as English,as they lack n-gender, whereas both strategies are applicable in ngenderlanguages, variably so for variable DPs, depending on th

Mechanical stimuli, such as wind, rain, and touch affect plant development, growth, pest resistance, and ultimately reproductive success. Using water spray to simulate rain, we demonstrate that jasmonic acid (JA) signaling plays a key role in early gene-expression changes, well before it leads to developmental changes in flowering and plant architecture. The JA-activated transcription factors MYC2

This paper discusses topicality in Icelandic grammar as realized in severalphenomena: referential third person pro drop in Old Icelandic, diverse typesof topic drop in Old and Modern Icelandic, and Narrative Inversion (declarativeVS clauses), also in both Old and Modern Icelandic. These phenomena all involveaboutness topics, given topics or both, thus showing that distinct types of topicality are This paper discusses topicality in Icelandic grammar as realized in several phenomena: referential third person pro drop in Old Icelandic, diverse types of topic drop in Old and Modern Icelandic, and Narrative Inversion (declarative VS clauses), also in both Old and Modern Icelandic. These phenomena all involve aboutness topics, given topics or both, thus showing that distinct types of topicality

Native speakers of Swedish use tones on stems to predict which suffix is to follow. This is seen behaviorally in reduced response times for matching tone-suffix pairs. Neurophysiologically, online prediction is reflected in the event-related potential (ERP) component pre-activation negativity (PrAN) occurring for tones with a higher predictive value. Invalid suffixes relative to the tone produce a

Forkhead box (Fox) transcription factors evolved early in animal evolution and represent important components of conserved gene regulatory networks (GRNs) during animal development. Most of the researches concerning Fox genes, however, are on vertebrates and only a relatively low number of studies investigate Fox gene function in invertebrates. In addition to this shortcoming, the focus of attenti

In Classical Athens, being at war was much more common than peace. The military expenditures were correspondingly large. The real enigmatic issue, however, is not financial but where they found the manpower needed for this policy. The number of warships (triremes) was so great that there is no way that the citizen could have dominated in the crews. The main source is likely the non-citizen, free p

The first measurement of the Υ(1S) elliptic flow coefficient (v2) is performed at forward rapidity (2.5

This study investigates the selection into lab experiments among university students based on data from two cohorts of a university’s first-year students. The analysis combines two experiments: a classroom experiment in which we elicited measures for risk, time, social preferences, confidence, and cognitive skills using standard measures from the experimental literature; and a recruitment experime

BACKGROUND: Factor affecting sperm retrieval rate (SRR) or pregnancy rates (PR) after testicular sperm extraction (TESE) in patients with non-obstructive azoospermia (NOA) have not been systematically evaluated. In addition, although micro-TESE (mTESE) has been advocated as the gold standard for sperm retrieval in men with NOA, its superiority over conventional TESE (cTESE) remains conflicting. OB