Stroke recovery research involves distinct biological and clinical targets compared to the study of acute stroke. Guidelines are proposed for the pre-clinical modeling of stroke recovery and for the alignment of pre-clinical studies to clinical trials in stroke recovery.

We present results from two experiments that provide the first quantification of inter-particle force networks in stiff, 3D, opaque granular materials. Force vectors between all grains were determined using a mathematical optimization technique that seeks to satisfy grain equilibrium and strain measurements. Quantities needed in the optimization - the spatial location of the inter-particle contact

The rheology of dense granular flows is studied numerically in a shear cell controlled at constant pressure and shear stress, confined between two granular shear flows. We show that a liquid state can be achieved even far below the yield stress, whose flow can be described with the same rheology as above the yield stress. A non-local constitutive relation is derived from dimensional analysis throu

In this work, we extend the popular sparse iterative covariance-based estimator (SPICE) by generalizing the formulation to allow for different norm constraint on the signal and noise parameters in the covariance model. For any choice of norms, the resulting generalized SPICE method enjoys the same benefits as the regular SPICE method, including being hyperparameter free, although the choice of nor

In this paper, we present a technique for reducing the size of the dictionary in sparse signal reconstruction by formulating an initial dictionary containing elements that spans bands of the considered parameter space. We allow for the use of this banded dictionary in a first-stage estimation procedure, in which large parts of the parameter space is discarded for further analysis, thereby reducing

Purpose: The purpose of this paper is to investigate how modern network video technology could be used to improve different warehouse types and operations and how barriers may prevent its implementation. Design/methodology/approach: An exploratory multiple-case study with nine case companies was conducted, including on-site visits, interviews, questionnaires and a workshop. Findings: The authors i

Purpose: The Swedish government is likely to implement longer and heavier road freight vehicles, so-called high-capacity vehicles (HCVs), in the near future. The purpose of this paper is to analysis the expected effects on the whole transport system regarding tonne-kilometres, vehicle-kilometres on road, CO2 and socio-economics with three possible implementation strategies (HCVs on all roads, a de

Abstract Voronoi diagrams are a general framework covering many types of concrete diagrams for different types of sites or distance measures. Generalizing a famous result by Aggarwal et al. we prove the following. Suppose it is known that inside a closed domain D the Voronoi diagram V(S) is a tree, and for each subset S'⊂S, a forest with one face per site. If the order of Voronoi regions of V(S) a

The absorption spectrum of the MnO4 - ion has been a test-bed for quantum-chemical methods over the last decades. Its correct description requires highly-correlated multiconfigurational methods, which are incompatible with the inclusion of finite-temperature and solvent effects due to their high computational demands. Therefore, implicit solvent models are usually employed. Here we show that impli

Purpose: The purpose of this paper is to link humanitarian logistics (HL) and supply chain risk management (SCRM) to provide an understanding of risk mitigation strategies that humanitarian organisations use, or could use, to improve their logistics preparedness. Design/methodology/approach: Based on systematic reviews of RMS in SCRM and supply chain strategies (SCS) in HL literature, a framework

A helicopter flying through an atmosphere containing particulates may accumulate high electrostatic charges which can challenge its operational safety. In this paper we report on the in uence of the helicopter configuration on its electrification. Our study is based on a recently developed numerical approach according to which the turbulent air flow around the rotorcraft is estimated via large edd

Lytic polysaccharide monooxygenases (LPMOs) are copper metalloenzymes that can enhance polysaccharide depolymerization through an oxidative mechanism, making them interesting for the production of biofuel from cellulose. However, the details of this activation are unknown; in particular, the nature of the intermediate that attacks the glycoside C–H bond in the polysaccharide is not known, and a nu

We present a framework to segregate the roles of elastic and non-elastic deformations in the examination of real-space experiments of solid-solid Martensitic transitions. The Martensitic transformation of a body-centred-tetragonal (BCT) to a body-centred-orthorhombic (BCO) crystal structure has been studied in a model system of micron-scale ionic microgel colloids (P. S. Mohanty, P. Bagheri, S. Nö

To date, scholarly understanding of external dimensions of market driving for the purposes of 'societal change' is largely unexplored in both developed and emerging market contexts. This paper uses a multiple case study approach to understand how market driving social enterprises (across the hybrid spectrum) create societal change in emerging markets. By drawing on Scott's (1995) three-part concep

Lytic polysaccharide monooxygenase (LPMO) enzymes have attracted considerable attention owing to their ability to enhance polysaccharide depolymerization, making them interesting with respect to production of biofuel from cellulose. LPMOs are metalloenzymes that contain a mononuclear copper active site, capable of activating dioxygen. However, many details of this activation are unclear. Some aspe

In many of the first treatment trials with tacrine, heterogeneity in treatment response was observed and discussed. One third of the patients were considered to be responders to treatment, one third unchanged and one third non-responders. Factors outlined as possible positive predictors of treatment were among others old age, well preserved frontal lobes, and presence of the APOE e4 allele. Unfort

Over the past three decades, a range of attempts have been made to raise the importance of science, technology and innovation on the policy agenda in Africa. This article explores four themes along which growth paths and patterns may be realized, namely regional and global integration, inclusive innovation, priorities and approaches to diversify African economies, and the role of the state. The ou

In presence of high allergen dosis besides IgE also IgG antibodies can induce allergic reactions, whose severity is dependent on the induced type of IgG Fc glycosylation, what should be considered for new AIT protocols containing new adjuvants.

Background: Socioeconomic status and geographical factors are associated with health and use of healthcare. Well-performing primary care contributes to better health and more adequate healthcare. In a primary care system based on patient's choice of practice, this choice (listing) is a key to understand the system. Objective: To explore the relationship between population and practices in a primar