Despite modern advances in the treatment of head and neck cancer, the survival rate fails to improve. Considering the different treatment modalities involved, quality of life has been thought of as an additional end point criterion for use in clinical trials. A Nordic protocol to measure the quality of life of head and neck cancer patients before, during, and after treatment was established. Befor

Allvarliga tillbud och olyckor inom flygtrafiken är relativt ovanligt, men när de inträffar ställs höga krav på kabinpersonalens förmåga att uppträda auktoritativt och effektivt. Det är dock inte bara vid ett direkt olyckstillbud det ställs stora krav på kabinpersonalens förmåga att hantera kritiska situationer. Det finns en hel flora av incidenter som kräver professionell hantering, t ex när passAlthough serious accidents or near-accidents are relatively rare in airline traffic, when they occur cabin attendants are expected to act effectively and with authority. However, the ability of cabin attendants to intervene professionally is also called for in other critical situations, such as when incidents that are frightening for the passengers occur or when passengers suddenly become ill. The

In this paper, problems related to simulation model documentation and model exchange between users are discussed. Complex simulation models have gained popularity in the environmental field, but require extensive documentation to allow independent implementation. The existence of different simulation platforms puts high demands on the quality of the original documentation. Recent experiences from

Det finns en stor potential för ett ökat utnyttjande av biomassa för energiändamål i Sverige. En ökad användning av biomassa skulle kunna bidra till att minska utsläppen av koldioxid från förbränning av fossila bränslen, minska beroendet av importerade fossila energibärare samt påverka den regionala och lokala miljösituationen såväl positivt som negativt. Föreliggande studie behandlar framför alltThere is a large potential for increasing the use of biomass for energy purposes in Sweden. Increasing the use of biomass can reduce emissions of carbon dioxide (CO2) from fossil-fuel combustion and dependence on imported fossil fuels. Furthermore, increased biomass use will affect emissions of other air pollutants than carbon dioxide as well as environmental impacts from land use. The study deals

Fatty acids, which are essential nutritional components, are also involved in cardiovascular and metabolic diseases. Here we report a human cell surface receptor that we name free fatty acid receptor (FFAR), because it is specifically activated by medium to long-chain free fatty acids. The receptor belongs to the class of seven-transmembrane, G-protein coupled receptors (GPCRs) and also mediates r

Airborne ultrafine particles (diameter

På Linköpings tekniska högskola har man tillgång till många olika sätt att mäta ättiksyra i en bioreaktor. Utrustningen för att mäta ättiksyra består av en NIR (near infrared spectroscopy) som mäter online och en samplingstid på sekund nivå kan uppnås. HPLC (high-performance liquid chromatography) finns det också tillgång till. Där räknar man med att ta prover var 15 min och att själva analysen ta

Objectives: The vascular biology of restenosis is complex and not fully understood, thus explaining the lack of effective therapy for its prevention in clinical settings. The role of c-Myc in arteriotomy-induced stenosis, smooth muscle cell (SMC) differentiation and apoptosis was investigated in rat carotids applying full phosphorothioate antisense ( AS) oligonucleotides (ODNs). Methods: Carotid a

Popular Abstract in Swedish En hjärtinfarkt, dvs död hjärtmuskel, uppstår då en del av hjärtats muskel inte blodförsörjs, exempelvis genom att en propp bildats i ett av hjärtats blodkärl. Detta tillstånd bör behandlas snarast möjligt för att rädda största möjliga del av hjärtmuskeln, eftersom en större infarkt innebär sämre pumpfunktion vilket ger patienten sämre prognos. Tidsförloppet för en hjärThe effect of duration of ischaemia on final infarct size is well established in animal studies, but not fully evaluated in humans. Delayed contrast-enhanced magnetic resonance imaging (DE-MRI) can be used to distinguish between viable and non-viable myocardium and thus to quantify infarct size. We therefore used DE-MRI to investigate how duration of ischaemia affects final infarct size normalized

The phase behaviour of mixtures of recombined milk membrane lipids dioleoylphosphatidylcholine (DOPC), sphingomyelin (SM), dioleoylphosphatidylethanolamine (DOPE), phosphatidylinositol (PI) and dioleoylphosphatidylserine (DOPS) in 60% water was examined as a function of temperature between 5 and 90 °C. The aim was to examine under which lipid composition the average properties turn from balanced o

The prevalence of obstructive lung diseases is increasing in Scandinavia and worldwide. The reasons for this are not known. The prevalence varies between countries but also between different areas within the same country. In northern Europe a north-south gradient and also an east-west gradient have been proposed. To our knowledge this is the first comprehensive epidemiological study concerning obs

This study examined the influence of affective personality, perfectionism, gender, arousal and dilemma content on moral reasoning. 264 participants were presented with moral dilemmas to which they had to provide a solution that reflected various degrees of justice and care. The results indicated that a) affective personality had an effect on moral reasoning, b) female participants reported higher

Measurements are presented of diffractive open charm production at HERA. The event topology is given by where the system X contains at least one charmed hadron and is well separated by a large rapidity gap from a leading low-mass proton remnant system Y. Two analysis techniques are used for the cross section measurements. In the first, the charm quark is tagged by the reconstruction of a D*±(2010)

This article deals with the concept of vicarious suffering in Is 53 and its relevance for present theological reflection and understanding of Christian belief. The issue is raised against the background of traditional critique of this concept, that is, its (bad) implications for both theology (e.g. F. Nietzsche) and anthropology (e.g. I. Kant). The article wants to contribute to this discourse by

In 19 consecutive patients with medial gonarthrosis, an arthroscopic examination with a biopsy of the load-bearing cartilage in the medial femoral condyle was undertaken at the same time as a proximal tibial osteotomy. A follow-up arthroscopic biopsy was performed on an average of 2 years after the osteotomy. In 9 knees there was an improvement in the cartilage quality, 8 knees were unchanged, whe

Heterozygosity-fitness correlations (HFCs) at noncoding genetic markers are commonly assumed to reflect fitness effects of heterozygosity at genomewide distributed genes in partially inbred populations. However, in populations with much linkage disequilibrium (LD), HFCs may arise also as a consequence of selection on fitness loci in the local chromosomal vicinity of the markers. Recent data sugges