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Popular Abstract in Swedish En typisk egenskap för de flesta proteiner är att de kan binda specifikt och reversibelt till olika ämnen. Välkända exempel är enzymer som kan binda till olika substrat och inhibitorer samt antikroppar som binder till antigen. Under min tid som doktorand vid avdelningen för mikrobiologisk ekologi vid Lunds universitet har jag studerat en grupp av proteiner i svamp som kLectins defined as non-enzyme, non-immunoglobulin carbohydrate binding proteins, have been found in a wide variety of viruses, bacteria, fungi, plants and animals. Although lectins have been purified from more than 60 different species of fungi, the structure and biological functions of these proteins are not well known. I examined the molecular structure of a lectin (designated AOL) isolated from

1. All monodeoxy TMSEt globotriosides (GbO3) and double-chain bis-sulfone GbO3-lipids were synthesised. The alpha-glycosylation with deoxygenated glycosyl donors (fluoride, ethylthio- and thiopyridin-2-yl-) was investigated in the syntheses of the TMSEt 2"-, 3",- 4"- and 6"-deoxy GbO3, and activation of the thiopyridin-2-yl-glycosides with AgOTf gave the best yield and selectivity. Glycosylation w

Min berättelse börjar med ett telefonsamtal i början på sommaren 1976, från Chefarbetsterapeuten på Universitetssjukhuset i Lund. Hon frågade om jag ville börja arbeta på Rehabiliteringsklinikens dagavdelning i Lund, med början i augusti. Jag skulle i samma veva just ringa besked till sjukhuset i Boden, där jag varit och tittat på jobb under sommaren. På 1970-talet var det vanligt att sjukhus i No

Popular Abstract in Swedish Den här avhandlingen beskriver elektrontransport i nanometerstora halvledarstrukturer vid mycket låga temperaturer (1 nanometer = 1 miljondels millimeter). De här strukturerna har helt andra elektriska egenskaper än vanliga ledare. Man ser effekter av enskilda elektroners transport, och av kvantmekaniska fenomen som kvantiserad energi och våginterferens. Området är föreIn this thesis, electron transport in mesoscopic semiconductor nanostructures, in particular so-called electron billiards or quantum dots, is studied. The thesis can be divided into two areas: the linear response regime of transport, and the nonlinear response regime of transport. The classical and quantum mechanical electron dynamics are studied for triangular and square-shaped electron billiard

We compare different block preconditioners in the context of parallel time adaptive higher order implicit time integration using Jacobian-free Newton–Krylov (JFNK) solvers for discontinuous Galerkin (DG) discretizations of the three dimensional time dependent Navier–Stokes equations. A special emphasis of this work is the performance for a relative high number of processors, i.e. with a low number

Computer-based design analysis is nowadays a common activity in most development projects. Used for design evaluation, verification, validation, or as a support for design exploration, it fulfils an important support function for the engineering designer, thus making it essential to have an operationally efficient and effective integration between both the engineering design and design analysis ac

This dissertation discusses the reception of Karl Barth in Swedish theology, with particular emphasis on the period since 1947. Harmonising tendencies arechar2cteristic of Swedish theology, and therefore, by its emphasis on discontinuity between I iod and man Barth's theology becomes the natural 'other' of Swedish theology. Barth's theoiogy is trivialised either through exclusion or through subsum

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Popular Abstract in Swedish Summary in swedish I en rad olika inflammatoriska sjukdomar såsom astma, reumatoid artrit och parodontit är makrofager involverade. Makrofager är vita blodkroppar som finns i kroppens olika vävnader. De reagerar på främmande partiklar, t ex bakterier, och bekämpar dessa genom att ”dels äta upp” främmande partiklar, sk fagocytos, och dels genom att utsöndra olika substaEicosanoids include prostaglandins, thromboxanes and leukotrienes, which are arachidonic acid oxygenation products. These lipids make important contributions to the signs and symptoms of inflammatory diseases. The level of free arachidonic acid seems to be a rate-limiting factor in the synthesis of eicosanoids and the enzyme cytosolic phospholipase A2 (cPLA2) has been shown to preferentially liber