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Fiber intake and total and cause-specific mortality in the European Prospective Investigation into Cancer and Nutrition cohort

Background: Previous studies have shown that high fiber intake is associated with lower mortality. However, little is known about the association of dietary fiber with specific causes of death other than cardiovascular disease (CVD). Objective: The aim of this study was to assess the relation between fiber intake, mortality, and cause-specific mortality in a large European prospective study of 452

Impulse oscillometry may be of value in detecting early manifestations of COPD.

BACKGROUND: Spirometry is used to diagnose chronic obstructive pulmonary disease (COPD). The Impulse oscillometry system (IOS) allows determination of respiratory impedance indices, which might be of potential value in early COPD, although previous experience is limited. We examined pulmonary resistance and reactance measured by IOS in subjects with or without self-reported chronic bronchitis or

Cancer risk among patients hospitalized for Type 1 diabetes mellitus: a population-based cohort study in Sweden

P>Aims Type 1 diabetes mellitus (T1DM) is an autoimmune disease with potential mechanistic links to immune-related cancers. We aimed at examining the overall and specific cancer risks among hospitalized T1DM patients from the national registers in Sweden. Methods A T1DM research cohort was created by identifying T1DM patients from the Hospital Discharge Register and linking them with the Cancer Re

Pro-Inflammatory Cytokines Reduce the Proliferation of NG2 Cells and Increase Shedding of NG2 In Vivo and In Vitro.

Neuron glial 2 (NG2) cells become strongly activated in injured brain areas. The activation is characterized by increased proliferation as well as increased expression and shedding of the proteoglycan NG2 expressed on their cell surface. It is currently not known how these cells respond to low-grade neuroinflammation provoked by systemic inflammation. To investigate this, we analyzed NG2 cell prol

A Dynamic Framework of Tourist Experiences: Spatial Temporalities and Performances in the Experience Economy

This article outlines a conceptual model that allows a discussion regarding tourist experiences. Through the notion and deconstruction of the concept experience design it is argued that in order to be able to analyze tourism and develop new innovative strategic approaches to tourism management, dynamic notions of space, time and performance have to be especially attended to. This is done through a

Microstructure evolution influenced by dislocation density gradients modeled in a reaction-diffusion system

Macroscopic properties of metallic materials are to a large extent dictated by the grain size and the presence and arrangement of grain boundaries. Plastic slip deformation will lead to the formation of dislocation pile-ups at grain boundaries, causing a heterogeneous distribution of dislocation density. This will on the macroscale manifest itself as a grain size dependence of the yield stress. Co

Inbreeding and homozygosity in breast cancer survival.

Genome-wide association studies (GWASs) help to understand the effects of single nucleotide polymorphisms (SNPs) on breast cancer (BC) progression and survival. We performed multiple analyses on data from a previously conducted GWAS for the influence of individual SNPs, runs of homozygosity (ROHs) and inbreeding on BC survival. (I.) The association of individual SNPs indicated no differences in th

Fin- eller fuletanol - vad avgör?

Syftet med denna studie är att beskriva etanols energieffektivitet och klimatnytta och hur dessa parametrar beror av lokala förutsättningar och beräkningsmetodik. Andra aspekter som påverkan på biologisk mångfald, arbetsmiljöförhållanden mm analyseras ej här. Fokus ligger på svensk spannmålsbaserad etanol men kopplingar görs till andra produktionssystem för etanol. Hur klimateffektiv etanol är som

Kanikerna i Dalby: tre studier

The Canons of Dalby. Three Studies I. When did the brothers in Dalby become Augustinians? There are different opinions among historians about what kind of community Egino founded in Dalby in the late 1060s. Some say it was Benedictine, others say it was a community of canons. Among the latter, some say they were regular canons, others that they were secular, and one distinguished historian has ev

Re-evaluation of the reaction rate coefficient of CH3Br + OH with implications for the atmospheric budget of methyl bromide

The reaction rate coefficient k(CH3Br + OH) has been determined in the temperature range 298-373 K, using pulse radiolysis/UV kinetic spectroscopy, and at 298 K using a relative rate method. The Arrhenius expression obtained from a fit to the experimental results is (2.9 +/- 0.9) x 10(-12) exp(-(1230 +/- 125)/T) cm(3) molecule(-1) s(-1), which is greater than the expression currently recommended.

Wideband 4×8 Array Antennas with Aperture Coupled Patch Antenna Elements on LTCC

We proposed a 4×8 array antenna with aperture-coupled patch antenna elements. The antenna was designed for 60 GHz operation and fabrication on the low-temperature cofired ceramic(LTCC) substrate(εr=5.8). The feedline with the stub was designed to enhance the radiating element bandwidth and the transition characteristics between the waveguide (WG) and microstrip line(MSL). Through the optimization

Studies on the Roles of PDGFRA and EGFR in the Classification and Identification of Therapeutic Targets for Human Gliomas

Popular Abstract in Swedish Gliom är den vanligaste typen av hjärntumörer hos vuxna. Den mikroskopiska klassificeringen av de olika formerna av gliom är subjektiv och i vissa fall t.o.m. felaktig, vilket leder till klinisk oklarhet som kan hindra utvecklingen av terapier som riktas mot speciella egenskaper som kännetecknar speciella typer av gliom. EGFR och PDGFRA är en cellreceptor som har en cenGlioma is the most common type of primary tumor in the adult central nervous system (CNS). However, the current classification of gliomas is highly subjective and even inaccurate in some cases, which leads to clinical confusion and hinders the development of targeted therapies. EGFR and PDGFRA play crucial roles in glia development and glioma pathogenesis. In this thesis we aim to establish a glia

Sex differences in learning ability in a common songbird, the great tit-females are better observational learners than males

In mammals, including humans, the most consistent cognitive sex difference appears to be a male advantage in spatial ability. Usually, some sex-correlated selective advantage is inferred to explain this, for example, the need for males to navigate over large territories. In birds, sex differences in learning abilities are rare. Here, we show that females of a common European songbird, the great ti

Evaluation of retinol binding protein 4 and carbamoylated haemoglobin as potential renal toxicity biomarkers in adult mice treated with Lu-177-octreotate

Background: The kidneys are regarded as one of the main dose-limiting organs in the treatment of neuroendocrine tumours with Lu-177-[DOTA(0), Tyr(3)]-octreotate (Lu-177-octreotate), despite the successful use of kidney uptake blocking agents such as lysine and arginine. To avoid renal toxicity but still give each patient as high amount of Lu-177-octreotate as possible, there is a need for methods/

Investigations of blue emitting phosphors for thermometry

Blue emitting phosphors are investigated and reported for possible use in thermometry. Currently reported thermographic phosphors in general have the drawback of long emission lifetimes obstructing the possibility to time gate for background discrimination. An additional problem is that many thermographic phosphors have emission in the red spectral region, making them vulnerable for black body rad

Transfer of tactile input from an artificial hand to the forearm: experiments in amputees and able-bodied volunteers

Abstract in UndeterminedPurpose:This study explores the possibilities of transferring peripheral tactile stimulations from an artificial hand to the forearm skin.Method:A tactile display applied to the forearm skin was used to transfer tactile input to the forearm from various locations on a hand displayed on a computer screen. Discernment of location, levels of pressure and a combination of the t