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Serine/threonine kinase 39 is a candidate gene for primary hypertension especially in women: results from two cohort studies in Swedes.

BACKGROUND: As recently pinpointed by a genome-wide association study the serine/threonine kinase 39 (STK39) is a candidate gene for hypertension. This kinase is strongly implicated in sodium reabsorption by the kidney through its modulating effect on furosemide-sensitive and thiazide-sensitive channels. The aim of our study was to test the effects of the STK39 rs35929607A>G polymorphism on blood

Detection of carbon using amplified laser-induced fluorescence

Radiative lifetimes and stimulated emission have been studied in two-photon-excited carbon atoms. A strong fluorescence enhancement was detected in the direction of the exciting laser beam. Rate equations for the energy levels involved have been calculated in order to obtain number densities from the emitted light. Lifetimes were measured for the 2p3p 3p and 3D states and for the A 3[Pi]g state of

Social capital, political trust, and health locus of control: A population-based study.

OBJECTIVE: To investigate the association between political trust in the Riksdag and lack of belief in the possibility to influence one's own health (external locus of control), taking horizontal trust into account. Design/setting/participants/measurements: The 2008 public health survey in Skåne is a cross-sectional postal questionnaire study with a 55% participation rate. A random sample of 28,19

Failure disjoint paths

Given a weighted directed graph where some arcs can fail while others are reliable, we aim to compute a shortest pair of failure-disjoint paths. If a reliable arc is used by both paths, its cost is counted only once. We present a polynomial time algorithm to solve the problem.

Hom-Lie Admissible Hom-coalgebras and Hom-Hopf Algebras

The aim of this paper is to generalize the concept of Lie-admissible coalgebra introduced by Goze and Remm to Hom-coalgebras and to introduce Hom-Hopf algebras with some properties. These structures are based on the Hom-algebra structures introduced by the authors.

Coffee Consumption and CYP1A2*1F Genotype Modify Age at Breast Cancer Diagnosis and Estrogen Receptor Status.

CYP1A2 plays a key role in the metabolism of both estrogen and coffee. Women with higher coffee intake and the CYP1A2*1F A/A genotype have a ratio of high 2-hydroxyestrone (2-OHE1) to 16alpha-OHE1. 2-OHE1 is a weak estrogen and may even block the estrogen receptor (ER), whereas 16alpha-OHE1 is procarcinogenic. We hypothesized that moderate to high coffee consumption (>/=2 cups per day) combined wi

Liberty, Law and Leviathan. Of Being Free from Impediments by Artifice

The argument in this paper is that Hobbes’ theory of freedom in Leviathan allows for four ways of being free to act – corporal freedom by nature, freedom from obligation by nature, the freedom to disobey, and the freedom of no-rule – each corresponding to a particular absence, some of which make sense only in the civil state. Contrary to what some have claimed, this complexity does not commit Hobb

Plasticity in hydraulic architecture of Scots pine across Eurasia

Widespread tree species must show physiological and structural plasticity to deal with contrasting water balance conditions. To investigate these plasticity mechanisms, a meta-analysis of Pinus sylvestris L. sap flow and its response to environmental variables was conducted using datasets from across its whole geographical range. For each site, a Jarvis-type, multiplicative model was used to fit t

Survival in cancer patients with previous hospitalization for sarcoidosis: a Swedish population-based cohort study during 1964-2006.

BACKGROUND: Sarcoidosis has been reported to be associated with an increased risk of cancer; however, little information is available about the prognosis for sarcoidosis patients diagnosed with cancer. PATIENTS AND METHODS: A population-based cohort of sarcoidosis patients was identified from Swedish registers. Cause-specific and overall hazard ratios (HRs) were estimated by using Cox regression m

Protein E of Haemophilus influenzae Is a Ubiquitous Highly Conserved Adhesin.

Protein E (PE) of nontypeable Haemophilus influenzae (NTHi) is involved in adhesion and activation of epithelial cells. A total of 186 clinical NTHi isolates, encapsulated H. influenzae, and culture collection strains were analyzed. PE was highly conserved in both NTHi and encapsulated H. influenzae (96.9%-100% identity without the signal peptide). PE also existed in other members of the genus Pas