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Validation of models to diagnose ovarian cancer in patients managed surgically or conservatively : multicentre cohort study

OBJECTIVE: To evaluate the performance of diagnostic prediction models for ovarian malignancy in all patients with an ovarian mass managed surgically or conservatively. DESIGN: Multicentre cohort study. SETTING: 36 oncology referral centres (tertiary centres with a specific gynaecological oncology unit) or other types of centre. PARTICIPANTS: Consecutive adult patients presenting with an adnexal m

A probabilistic approach to evaluate the risk of decreased total triiodothyronine hormone levels following chronic exposure to PFOS and PFHxS via contaminated drinking water

BACKGROUND: Extensive exposure to per-and polyfluoroalkyl substances (PFAS) have been observed in many countries. Current deterministic frame-works for risk assessment lack the ability to predict the likelihood of effects and to assess uncertainty. When exposure exceeds tolerable intake levels, these shortcomings hamper risk management and communication. OBJECTIVE: The integrated probabilistic ris

Positive effects of co-inoculation with Rhizophagus irregularis and Serendipita indica on tomato growth under saline conditions, and their individual colonization estimated by signature lipids

Tomato roots can be colonized by both mycorrhizal fungi and the endophytic fungus Serendipita indica. This study was aimed at assessment of the impact of single or dual inoculation with R. irregularis and S. indica on tomato growth under saline conditions. We used signature compounds to estimate the abundance of each of these two fungi (fatty acid 16:1ω5 for R. irregularis and ergosterol for S. in

Science Goals and Mission Objectives for the Future Exploration of Ice Giants Systems : A Horizon 2061 Perspective

The comparative study of planetary systems is a unique source of new scientific insight: following the six “key science questions” of the “Planetary Exploration, Horizon 2061” long-term foresight exercise, it can reveal to us the diversity of their objects (Question 1) and of their architectures (Question 2), help us better understand their origins (Question 3) and how they work (Question 4), find

Chronic pain 1–5 years after heart transplantation—A nationwide cross-sectional cohort study

Aim: To provide a multidimensional assessment of self-reported chronic pain 1–5 years after heart transplantation and its relationship with self-reported well-being, fatigue, recovery, self-efficacy and socio-economic factors and to explore differences between heart recipients and a cohort of lung recipients. Design: This multicentre, cross-sectional, cohort study is a part of the Swedish national

Low-level cadmium exposure is associated with decreased cortical thickness, cortical area and trabecular bone volume fraction in elderly men : The MrOS Sweden study

It is well known that high-level exposure to cadmium can cause bone disease such as osteoporosis, osteomalacia and fractures. However, the effect of low-level exposure, as found in the general population (mainly derived from diet and smoking), has only been assessed recently. The aim of this study was to examine if cadmium exposure in the general Swedish population causes other bone changes than d

Recommendations for the management of patients with immune-mediated kidney disease during the severe acute respiratory syndrome coronavirus 2 pandemic

The coronavirus disease 2019 (COVID-19) pandemic has created major challenges for all countries around the globe. Retrospective studies have identified hypertension, cardiovascular disease, diabetes and older age as risk factors for high morbidity and mortality from COVID-19. There is a general concern that patients with immune-mediated kidney diseases, namely those on immunosuppressive therapies

Surgical Complications in Postchemotherapy Retroperitoneal Lymph Node Dissection for Nonseminoma Germ Cell Tumour : A Population-based Study from the Swedish Norwegian Testicular Cancer Group

BACKGROUND: Reports on perioperative complications after postchemotherapy retroperitoneal lymph node dissection (PC-RPLND) for nonseminoma germ cell tumour (NSGCT) are from experienced single centres, with a lack of population-based studies. OBJECTIVE: To assess the complications of bilateral and unilateral PC-RPLND. DESIGN, SETTING, AND PARTICIPANTS: A prospective, population-based, observational

Rolling Shutter Camera Absolute Pose

We present minimal, non-iterative solutions to the absolute pose problem for images from rolling shutter cameras. The absolute pose problem is a key problem in computer vision and rolling shutter is present in a vast majority of today's digital cameras. We discuss several camera motion models and propose two feasible rolling shutter camera models for a polynomial solver. In previous work a lineari

Development and content validity evaluation of a candidate instrument to assess image quality in digital mammography : A mixed-method study

Purpose: To develop a candidate instrument to assess image quality in digital mammography, by identifying clinically relevant features in images that are affected by lower image quality. Methods: Interviews with fifteen expert breast radiologists from five countries were conducted and analysed by using adapted directed content analysis. During these interviews, 45 mammographic cases, containing 44

The Angantyr model for heavy ions in Pythia8

Pythia8 is the only general purpose event generator able to produce complete fully exclusive hadronic final states in collisions involving heavy ions. The model that allows this is called Angantyr and will be discussed in this contribution. The contribution also discusses models based on interactions between strings in an extention of the Lund model that are able to describe some collective effect

Essential fragmentation metrics for agricultural policies : Linking landscape pattern, ecosystem service and land use management in urbanizing China

Fragmentation, as one of the most distinct characteristics of agricultural landscapes worldwide, has resulted in a diversity of ecological consequences. It remains as a gap in the literature on how provisioning service changes in association with agricultural fragmentation and land use management. Addressing such a gap at a national level should provide essential insights for policymakers. This pa

Identification of two additional behaviorally active gland constituents of female Diatraea saccharalis (Fabricius) (Lepidoptera Crambidae)

The sugarcane borer, Diatraea saccharalis (Fabricius), is the major pest insect attacking sugarcane crops in Brazil. Population control by insecticide treatment is not efficient due to simultaneous presence of all developmental stages of the insect throughout the year, and alternative control methods are needed. Two female-produced sex pheromone components, (Z,E)-hexadeca-9,11-dienal and (Z)- hexa

An investigation on early evolution of soot in n-dodecane spray combustion using large eddy simulation

Numerical simulations using large eddy simulation (LES) and Unsteady Reynolds Averaged Navier–Stokes (URANS) are carried out to identify the underlying mechanisms that govern the early soot evolution process in an n-dodecane spray flame at 21% O2 by molar concentration. A two-equation phenomenological soot model is used here to simulate soot formation and oxidation. Both ignition delay time (IDT)

Combustion characteristics of n-heptane spray combustion in a low temperature reform gas/air environment

This paper presents a large eddy simulation study of n-heptane spray combustion in an n-heptane low temperature reform (LTR) gas environment in a constant volume combustion chamber, under conditions relevant to single-fuel reactivity controlled compression ignition (RCCI) combustion engines. The LTR gas is made up of partially oxidized intermediate species from rich n-heptane/air mixture in an ext

The fabrication of atomically thin-MoS2 based photoanodes for photoelectrochemical energy conversion and environment remediation : A review

Photoelectrochemical (PEC) technology has been proved a promising approach to solve the problems of energy shortages and environmental pollution damages. It can convert unlimited solar energy resources into energy forms needed by mankind. The development of highly efficient photoanodes is a key step in realizing the large-scale practical application of PEC systems. However, the development of PEC

Paso doble : A two-step Late Pleistocene range expansion in the Tyrrhenian tree frog Hyla sarda

The Tyrrhenian tree frog, Hyla sarda, is an amphibian endemic to the Tyrrhenian islands (Western Mediterranean). Previous investigations of its Pleistocene evolutionary history suggested that it colonised the northern portion of its current range, through a spatial diffusion process from the Sardinia island, during the last glaciation. However, southern and northern portions of the species’ range

Tuning electrochemically driven surface transformation in atomically flat LaNiO3 thin films for enhanced water electrolysis

Structure–activity relationships built on descriptors of bulk and bulk-terminated surfaces are the basis for the rational design of electrocatalysts. However, electrochemically driven surface transformations complicate the identification of such descriptors. Here we demonstrate how the as-prepared surface composition of (001)-terminated LaNiO3 epitaxial thin films dictates the surface transformati