Filetype
Patients diagnosed with diffuse large B-cell lymphoma (DLBCL) show varying responses to conventional therapy, and this might be contributed to the differentiation stage of the tumor B-cells. The aim of the current study was to evaluate a panel of kinases (ZAP70, PKC-beta I and II and phosphorylated PKB/Akt) and phosphatases (PTEN, SHP1 and SHP2) known to be frequently deregulated in lymphoid malig
In Sweden a new red list was issued 2000, but there is no published list of the most important areas for biodiversity preservation. I use woodliving and red-listed beetles as indicators of “hot-spots” for biodiversity preservation, since these insects constitute a large proportion of the red-listed forest living species in Sweden. Based on museum and many large private collections of beetles from
[abstract missing]
Recension av Michelle Facos, Nationalism and the Nordic Imagination. Swedish Art in the 1890s.
The lactate dehydrogenase (LDH) activity and isoform distribution of LDH were investigated in tissue samples from the rat portal vein, aorta and urinary bladder. In addition, samples were obtained from hypertrophic urinary bladder. The total LDH activity per unit smooth muscle volume was higher in the urinary bladder compared to that in portal vein and aorta. Five LDH isoforms, reflecting differen
Cetyltrimethylammonium surfactants with a range of oligo carboxylate anions bearing. 2, 3, or 4 negative charges have been synthesized, and their respective behaviors in binary mixtures with water and in ternary mixtures with added decanol have been investigated. In binary mixtures with water, all surfactants formed nearly spherical micelles at high water contents; however, the interactions betwee
Car developers use digital human modeling tools to analyze and visualize car interiors in relation to human characteristics before the vehicles are actually constructed. Developers, reviewers and users of human simulation tools often claim that such tools can reduce development time and costs. In car industry companies today, human simulation tools are used by a single or a few experts in an infor
Objective. A refrigerator-stable formulation of ProQuad has been developed to expand the utility of ProQuad to areas in which maintenance of a frozen cold chain (- 15 degrees C or colder) during storage and transport may not be feasible. The objective of this study was to demonstrate that the immunogenicity and safety profiles of a refrigerator-stable formulation of ProQuad are similar to the rece
We apply the orthogonal portfolio approach to analyse the importance of risk factors potentially missing from the CAPM. We generalize the approach proposed by MacKinlay and Pastor (2000) [MacKinlay, A.C., Pastor, L., 2000. Asset pricing models: implications for expected returns and portfolio selection. Review of Financial Studies 13, 883–916] by estimating the Sharpe ratio of the optimal orthogona
Breast and prostate cancer preferentially metastasize in the skeleton, inducinglocally increased bone resorption by osteoclasts. Bisphosphonates (BPs), potent inhibitors of osteoclasts and bone resorption, are able to reduce metastatic bone lesions, but the metastasis-related cellular target molecules for BPs have not yet been identified. In osteoclasts, nitrogen-containing BPs inhibit the functio
In the Swedish National Care Programme for Hodgkin's lymphoma (HL) a less intensive chemotherapy regimen with individualized dosing (LVPP/OEPA) was introduced in 1989. In total, 139 patients, 77 between 1985 and 1988 and 62 between 1989 and 1992, were studied. Mean ages were 72 and 71 years, respectively. One hundred and nineteen patients were treated with curative intention, 63 (82%) between 1985
