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Niche recycling through division-independent egress of hematopoietic stem cells

Hematopoietic stem cells (HSCs) are thought to reside in discrete niches through stable adhesion, yet previous studies have suggested that host HSCs can be replaced by transplanted donor HSCs, even in the absence of cytoreductive conditioning. To explain this apparent paradox, we calculated, through cell surface phenotyping and transplantation of unfractionated blood, that similar to 1-5% of the t

Reactivity of phenyldi(2-thienyl) phosphine towards group 7 metal carbonyls: Carbon-phosphorus bond activation

Addition of phenyldi(2-thienyl) phosphine (PPhTh2) to [Re-2(CO)(10-n)(NCMe)(n)] (n = 1, 2) affords the substitution products [Re-2(CO)(10-n)(PhPTh2)(n)] (1, 2) together with small amounts of fac-[ClRe(CO)(3)(PPhTh2)(2)] (3) (n = 2). Reaction of [Re-2(CO)(10)] with PPhTh2 in refluxing xylene affords a mixture which includes 2, [Re-2(CO)(7)(PPhTh2)(mu-PPhTh)(mu-H)] (4), [Re-2(CO)(7)(PPhTh2)(mu-PPhTh

A Gradient-Enhanced Continuum Damage Model for Residually Stressed Fibre-Reinforced Materials at Finite Strains

The modelling of damage effects in materials constitutes a major challenge in various engineering-related disciplines. However, the assumption of purely local continuum damage formulations may lead to ill-posed boundary value problems and—with regard to numerical methods such as the finite element method—to mesh-dependent solutions, a vanishing localised damage zone upon mesh refinement, and hence

A toxicological and dermatological assessment of alkyl cyclic ketones when used as fragrance ingredients The RIFM Expert Panel

The alkyl cyclic ketone (ACK) fragrance ingredients are a diverse group of structures with Similar metabolic and toxicity profiles. ACK fragrance materials demonstrate low acute toxicity. Upon repeat dose testing, some adverse effects in biochemical and hematological parameters, and slightly increased liver and kidney weights were reported, primarily at high doses, resulting from adaptive effects.

Valence bond liquid phase in the honeycomb lattice material Li2RuO3

The honeycomb lattice material Li2RuO3 undergoes a dimerization of Ru4+ cations on cooling below 270 degrees C, where the magnetic susceptibility vanishes. We use density functional theory calculations to show that this reflects the formation of a valence bond crystal, with a strong structural bond disproportionation. On warming, x-ray diffraction shows that discrete threefold symmetry is regained

Hydrogen intercalation of graphene grown on 6H-SiC(0001)

Atomic hydrogen exposures on a monolayer graphene grown on the SiC(0001) surface are shown to result in hydrogen intercalation. The hydrogen intercalation induces a transformation of the monolayer graphene and the carbon buffer layer to bi-layer graphene without a buffer layer. The STM, LEED, and core-level photoelectron spectroscopy measurements reveal that hydrogen atoms can go underneath the gr

Unveiling the Pandemic Paradox

Purpose: This paper aimed to present new insights into how Covid-19 has affected the European IPO market both in the short and long-term and how underlying factors can explain this phenomenon. Additionally, the paper's findings provide valuable insights into the effects of the pandemic on financial markets. It can help investors and policymakers to better understand the risks and opportunities

Improving life situations through scholarship programs - The case of Tanzanian beneficiaries

Det fjärde globala målet i 2030 års agenda för hållbar utveckling handlar om God utbildning för alla och syftar till att "säkerställa en inkluderande och likvärdig utbildning av god kvalitet och främja livslångt lärande för alla". Globalt sett ökar antalet studenter vid universitet och högskolor. Dock ligger regionen söder om Sahara långt efter och har med sina 9% den lägsta bruttoinskriThe fourth goal of the 2030 Agenda for Sustainable Development regards Quality education, aiming to “ensure inclusive and equitable quality education and promote lifelong learning opportunities for all". Globally, enrollment in university education is increasing. However, the sub-Saharan Africa region is lacking behind and with 9% it has the lowest global gross enrollment rate (GER). Low inco

Towards a Sustainable Energy Future: A Case Study of Luxembourg’s Transition to Renewable Energy and Carbon Neutrality

Climate change poses a significant threat to humanity, with devastating consequences already occurring. Transitioning to a low-carbon economy is crucial for mitigating the effects of climate change. High per capita energy consumption and emissions make this transition an urgency for Luxembourg. This study focuses on the sustainable energy transition in Luxembourg, examining challenges and opportun

Scope of Labour Law, Negative Freedom of Association and Minimum Wage Setting - Comparing Japan and EU

This essay compares the labour law regulations in Japan and EU/Sweden. The focus of the paper is the definition of workers, negative freedom of association, and minimum wage settings. This paper firstly illustrates who is classified as a ‘worker’ and discusses the issues of unclear categorisation of platform workers and the potential impact of gigification in the labour markets. The EU proposal re

Investigating House Price Predictors: A Random Forest Application

In macroeconomics, the housing market has been well-researched due to its significance for economic and financial stability. This study investigated the predictive importance of selected fundamental and non-fundamental determinants of house price in three different markets: the United States, Sweden, and Japan, across three different periods. By applying a random forest model, this thesis attempte

Foreign Exchange Rate Derivatives and Firm Value

Using Tobin’s Q as an approximation of firm value, this paper aims to examine the effect of foreign exchange rate derivatives on firm value. Risk management is viewed by many as one of the most vital aspects of corporate- and business strategy. On the topic of risk, foreign exchange rate exposure is a distinctive form of risk confronted by numerous internationally operating firms. The mitigation o

Hur man behåller anställda inom transportbranschen

Sammanfattning Examensarbetets titel: Förbli på rätt spår: En uppsats om hur man behåller anställda inom transportbranschen. Seminariedatum: 2023-06-01 Ämne/kurs: FEKH69, Examensarbete i redovisning på kandidatnivå, 15 högskolepoäng Författare: Max Brigge, Ebba Kilström och Gustaf Mannerstam Handledare: Anna Glenngård Nyckelord: Incitament, motivation, transportbranschen, personalomsättning Abstract Title: "On the Right Track: Employee Retention Strategies in the Transport Industry" Seminar date: 2023-06-01 Course: FEKH69, Degree Project Undergraduate level, Business Administration, Undergraduate level, 15 University Credit Points (UPC) or ECTS-credits Authors: Max Brigge, Ebba Kilström och Gustaf Mannerstam Supervisor: Anna Glenngård Key words: Incentives, motivati

Tradition vs. Human Rights? Analyzing Racialized Branding from a Business and Human Rights Perspective

Systemic racism is a prevalent and longstanding problem in society that gained widespread public interest through the Black Lives Matter movement. Following the murder of George Floyd in May 2020, the movement expanded to Austria and brought heightened attention to the racialized branding of an Austrian brewery. Here, this expansion contributed to an existing resistance of the NO MOHR campaign aga

How is carbon stored in boreal forest soils? - A method development which investigates at what protein concentration ferrihydrite and goethite are saturated.

Marken är en viktig spelare när det kommer till att lagra kol, särskilt i boreala skogar. Dessa skogar lagrar nämligen största delen av sitt kol i jorden och fungerar som en viktig kolsänka. Men vi vet faktiskt inte helt vad det är som styr detta. Ny forskning har dock lyft ektomykorrhizasvampar som en viktig faktor. Mer konkret så föreslås nu ektomykorrhizasvampars förmåga att frigöra grundämnet Boreal forests store the majority of their carbon in the soil and play an important role in the global carbon cycle. However, the mechanisms that control carbon storage in boreal soils are not well understood. In recent studies, there has been a specific focus on how ectomycorrhizal (ECM) fungi influence carbon dynamics in boreal forests, particularly through their nitrogen acquisition. A major pa

Quantifying the Swiss Custom Strategy and Its Impact on Economic Development from 1870 to 1913

The late 19th century witnessed a remarkable surge in globalization, resulting in a substantial flow of goods, labour, and capital across national and continental borders. Switzerland, despite its limited domestic market and resource constraints, capitalized on this era of globalization and transformed itself from a relatively impoverished agrarian state to one of the world's wealthiest nation

Associativ språkinlärning med händerna - Lär vi oss språk bättre i en kontext?

I studien undersöktes associativ språkinlärning via Virtual Reality (VR) och jämfördes sedan med en mer traditionell ordinlärning via en datorskärm, för att se om det förekom någon skillnad i inlärningen mellan dessa. Syfte. Studien syftade till att undersöka om inlärning av ett nytt språk gynnas av associativ inlärning med flera av våra sinnen genom VR. Vår hypotes var att språkinlärning kan gynThe study examined associative language learning through Virtual Reality (VR) and then compared it to more traditional word learning through a computer screen, in order to see if there was any difference in learning between these two. Purpose. The aim of this study to investigate whether learning a new language benefits from associative learning, with several of our senses, through VR. Our hypoth

Community-based Water Management for Sustainable and Collective Action in Rural Costa Rica

The aim of this study was to deepen the understanding of how community-based water management approaches facilitate sustainable and collective action (SCA) in the context of increasing water insecurity in Costa Rica. Applying a qualitative approach, based on fieldwork in Guanacaste, Costa Rica, including semi-structured interviews and a digital community survey, the study uncovers facilitating fac

Design, synthesis, and evaluation of 4-aryltriazolyl threitol derivatives as galactose-mimicking inhibitors of galectin-3

Galektiner är proteiner som finns i människor och i de flesta andra djur. De binder till kolhydrater, särskilt de som innehåller galaktos och förekommer naturligt på cellernas yta och omgivning. Galektinernas interaktion med kolhydrater gör att de spelar stor roll i en rad olika biologiska processer, bland annat kommunikation mellan celler, celldöd och celltillväxt. Idag finns 15 olika identifieraGalectins are small soluble proteins that bind to carbohydrates. They have a high affinity for glycoconjugates containing galactose that exist naturally on the surface of cells and in the extracellular surroundings. This allows them to be involved in many different physiological and pathological process in the human body. Galectin-3, that is the focus in this report, works proinflammatory which no

När infaller lovplikten för ridanläggningar? - En studie av skillnaden mellan idrottsplats och idrottsanläggning

Ridanläggningar är både arealkrävande och påverkande på sin omgivning ändock är det inte helt självklart huruvida dessa anläggningar kräver bygglov eller ej. Likväl är begreppen idrottsplats och idrottsanläggning inte heller helt självklara vad de innebär och speciellt inte i förhållande till en ridanläggning, det vill säga under vilken av definitionerna som en ridanläggning platsar. Syftet med deKnowing whether a riding facility requires a building permit or not is not always straightforward. Neither is it easy to understand how a riding facility compares to a sports field or sports facility. The aim of this thesis is therefore to define the differences between the definitions and understand how the duty of permit is affected by the definition of the riding facility. It is also investigat