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Novel diagnostic methods and potential treatments in cardiovascular autonomic dysfunction

General Aim: To investigate novel diagnostic tools and treatment options for cardiovascular autonomic dysfunction (CVAD) patients, focusing on syncope, orthostatic intolerance, and heart failure (HF).Background: CVAD includes common clinical entities such as vasovagal syncope (VVS) postural orthostatic tachycardia syndrome (POTS) and orthostatic hypotension (OH). Also, CVAD plays an important role

To wear or not to wear, was that the question? Understanding citizen responses to COVID-19 crisis management in social media across Europe

This study aims to gain qualitative insights about and compare public responses to COVID-19 crisis management during the different pandemic phases and across three countries—Norway, Sweden and Italy. To do so, we have carried out a qualitative content analysis of a selection of 2606 tweets containing the term ‘face mask’ in Italian, Norwegian, and Swedish published between March 1, 2020 and June 3

Distinct Infiltration of T Cell Populations in Bladder Cancer Molecular Subtypes

Bladder cancer is a heterogenous disease, and molecular subtyping is a promising method to capture this variability. Currently, the immune compartment in relation to subtypes is poorly characterized. Here, we analyzed the immune compartment in bladder tumors and normal bladder urothelium with a focus on T cell subpopulations using flow cytometry and RNA sequencing. The results were investigated in

Care according to age: A case of ageism or a conflict on needs?

Despite a strong emphasis that individual support services should be provided according to needs, the Swedish welfare system often use age to organize support. A change in the Social Service Act in 2018 allows municipalities to provide home care for people above a decided age without individual any assessment of needs. Political parties and pensioners’ organizations’ have proposed for the introduc

Tillitsstyrning istället för minutscheman är bra – men glöm inte att hjälpen är till för de äldre.

Istället för att kräva sin rätt har äldre förståelse för personalens stressiga situation och accepterar att inte få sina behov tillgodosedda, skriver Håkan Jönson, Tove Harnett och Glenn Möllergren, forskare vid Socialhögskolan i Lund.Företrädare för Kristdemokraterna i Malmö, Lars Hector, Anna Reimer och Henrik Reimer, kritiserar den så kallade minutstyrningen inom hemtjänsten i staden och förkla

The fifth international hackathon for developing computational cloud-based tools and resources for pan-structural variation and genomics

BackgroundThe goal of the Fifth Annual Baylor College of Medicine & DNAnexus Structural Variation Hackathon was to push forward the research on structural variants (SVs) by rapidly developing and deploying open-source software. The event took place in-person and virtually in August 2023, when 49 scientists from 14 countries and 8 U.S. states collaboratively worked on projects to address critic

Long-term toxicity and efficacy of FLASH radiotherapy in dogs with superficial malignant tumors

Introduction: FLASH radiotherapy (RT) has emerged as a promising modality, demonstrating both a normal tissue sparing effect and anticancer efficacy. We have previously reported on the safety and efficacy of single fraction FLASH RT in the treatment of oral tumors in canine cancer patients, showing tumor response but also a risk of radiation-induced severe late adverse effects (osteoradionecrosis)

Bloch equations in terahertz magnetic-resonance ellipsometry

A generalized approach derived from Bloch's equation of motion of nuclear magnetic moments is presented to model the frequency, magnetic field, spin density, and temperature dependencies in the electromagnetic permeability tensor for materials with magnetic resonances. The resulting tensor model predicts characteristic polarization signatures which can be observed, for example, in Mueller matrix e

Child-to-adult transition : a survey of current practices within the European Reference Network for Rare Neurological Diseases (ERN-RND)

Background: Transition from child-centered to adult-centered healthcare is a gradual process that addresses the medical, psychological, and educational needs of young people in the management of their autonomy in making decisions about their health and their future clinical assistance. This transfer is challenging across all chronic diseases but can be particularly arduous in rare neurological con

Geometry of plastic deformation in metals as piecewise isometric transformations

Deformation mechanisms of crystalline solids has been the subject of research for more than two centuries. The theory of dislocations dominates modern views but still has significant gaps demanding the introduction of additional concepts for the coherent quantitative description of physical phenomena. In this work, we propose a coherent geometric description of motion and deformation in crystallin

The impact of order fulfillment on consumer experience : text mining consumer reviews from Amazon US

Purpose – This research analyzes online consumer reviews and ratings to assess e-retail order fulfillment performance. The study aims to (1) identify consumer journey touchpoints in the order fulfillment process and (2) determine their relative importance for the consumer experience.Design/methodology/approach – Text mining and analytics were employed to examine over 100 m online purchase orders,