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Leukotriene antagonists are effective in the treatment of exercise-induced bronchoconstriction. Montelukast is a specific cysteinyl-leukotriene receptor1 antagonist without known effects on the pulmonary vessels, which in theory should be advantageous with respect to gas exchange. In addition to lung function, we investigated the effects of montelukast on parameters of gas exchange and physical pe

Human alpha 1-microglobulin (alpha 1-m), a 26 kilodalton serum glycoprotein, was found to exert mitogenic effects on human peripheral blood lymphocytes (PBL) in serum-free medium. Purified T cells, but not B cells, responded with proliferation to alpha 1-m, but only in the presence of monocytes. The mitogenic activity could be partially neutralized by a mouse monoclonal antibody against alpha 1-m.

Religion and intersectionality Categories frequently discussed in terms of intersectionality are gender, class, race, ethnicity and sexual orientation. This paper argues that religion often is a relevant dimension in intersectional analyses. Religion may not be inevitable as the other dimensions, but in large parts of the world it is nevertheless an unavoidable social element and even in the secu

Among psychiatric illnesses, genetically determined disorders usually have an early onset and a severe and complicated course. Gene-environmental interaction is of importance for aggressive impulsive behaviour. For example, alcoholism type II has a high family loading, a severe course, and is often associated with antisocial behaviour. In order to gain further understanding of aggressive and impul

Alanine metabolism in the ectomycorrhizal fungus Paxillus involutus was investigated using [N-15]alanine. Short-term exposure of mycelial discs to [N-15]alanine showed that the greatest flow of N-15 was to glutamate and to aspartate. Levels of enrichment were as high as 15-20% for glutamate and 13-18% for aspartate, whereas that of alanine reached 30%. Label was also detected in the amino-N of glu

Genome-wide nonparametric linkage analysis of 480 sib-pairs affected with type 2 diabetes revealed linkage to a previously unreported susceptibility locus on chromosome 18p11. This result improved with stringent subphenotyping using age- and sex-adjusted BMI, ultimately reaching a logarithm of odds of 3.82 (allele sharing 0.6654) at a point between markers D18S976 and D18S391 when the most obese 2

Members of the parasitic dinoflagellate genus Amoebophrya lethally infect other marine dinoflagellates, including red tide forming and toxin-producing species. The known geographical distribution of Amoebophrya sp. parasites in costal waters of the northern hemisphere is more likely reflecting a lack of information from other areas rather than the actual picture. We investigated the presence of Am

The big Malmö newpapers Sydsvenska Dagbladet and Kvällsposten, both owned by the family Wahlgren, involved themselves heavily in Swedish party politics in the 1960s. The Social Democrats had in 1962 been in almost permanent power in Sweden since 1932. There was a desperate wish for change in power among many Swedishy voters. In this atmosphere Olof Wahlgren, Sydsvenska Dagbladet´s deputy editor,