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Genetics of autoimmune diseases: a multistep process.
Abstract in UndeterminedIt has so far been difficult to identify genes behind polygenic autoimmune diseases such as rheumatoid arthritis (RA), multiple sclerosis (MS), and type I diabetes (T1D). With proper animal models, some of the complexity behind these diseases can be reduced. The use of linkage analysis and positional cloning of genes in animal models for RA resulted in the identification of
Utvärdering av cykelfälts effekter på cyklisters säkerhet och cykelns konkurrenskraft mot bil
Popular Abstract in Swedish Cykeln som transportmedel har många fördelar för individ och samhälle. Det är ett mycket energisnålt transportmedel, det förorenar inte, bullrar inte, tar liten plats och ger dem som cyklar välbefinnande och motion. Om fler cyklade istället för att åka bil skulle detta medföra trevligare stadsmiljöer. Ökad cykling hade också kunnat bidra till en ökad folkhälsa. För närThis work presents an evaluation of bicycle lane effects on cyclist safety and the ability of bicycles to compete with car traffic. Thirteen Swedish urban streets were studied before and after bicycle lanes were introduced. Data was collected using video recordings, speed studies, road side questionnaires/interviews with cyclists/car drivers, conflict studies and accident analysis. Results showed
Statsvetenskaplig metodologi i arbete : en utvärdering
Sambandet mellan kunskapssyn, undervisning och examinationsformer på 20-poängskursen i statsvetenskap vid Lunds Universitet.
Synthesis of boronate-contaming copolymers of N,N-dimethylacrylamide, their interaction with poly(vinyl alcohol) and rheological behaviour of the gels
Cross-linking of polyvinylalcohol (PVA) by boronate-containing copolymer of N,N-dimethylacrylamide (DMAA, 1) was studied and compared to cross-linking of PVA by borate buffers in weakly alkaline solutions. The copolymer of M-w = 19,000 g mor(-1) containing 9 mol% N-acryloyl-m-aminophenylboronic acid (NAAPBA, 2) was prepared by free radical polymerization of the monomers, exhibiting copolymerizatio
Hypoglycemic brain injury. II. Electron-microscopic findings in rat cerebral cortical neurons during profound insulin-induced hypoglycemia and in the recovery period following glucose administration
Severe hypoglycemia was induced in rats by insulin. The brain was fixed in situ by perfusion after the spontaneous EEG had disappeared for 30 or 60 min or after recovery had been induced for 30 or 180 min by glucose injection. Samples from the cerebral cortex from the area corresponding to the previous metabolic studies were processed for electron microscopy. The light-microscopic finding of two d
First-trimester diagnosis on chorionic villi obtained by direct vision technique
An improved technique for direct vision chorionic biopsy that gives a clear view of the amniotic sac was developed. With this technique, used in 48 women prior to vacuum aspiration and in six cases for diagnosis (karyotyping or enzyme analysis), it was possible to obtain chorionic villi free from contamination by maternal tissue. It was also possible to pick out villi (rich in blood vessels and wi
Secondary maternal cytomegalovirus infection - A significant cause of congenital disease
Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium
Cellular cardiomyoplasty is an attractive option for the treatment of severe heart failure. It is, however, still unclear and controversial which is the most promising cell source. Therefore, we investigated and examined the fate and functional impact of bone marrow (BM) cells and embryonic stem cell (ES cell)-derived cardiomyocytes after transplantation into the infarcted mouse heart. This proved
Exhibition enterprising: Six cases of realisation from idea to institution
No title
"al-Kaskari and as-Sukkari". A possible solution to the question of authorship of a treatise attributed to Yahya ibn Adi
Re: CYP17 promoter polymorphism and breast cancer in Australian women under age forty years
No title
A service life model for internal frost damage in concrete
The idea behind the service life model presented in this report was published in 1979. It has thereafter been described and developed in a number of reports and papers. The basis of the model is the observation that a well-defined critical, or maximum allowable, moisture content exists, above which the material is severely damaged by frost, and below which it is unharmed also when freezing is repe
Changes in height, weight, and body mass index in children with craniopharyngioma after three years of growth hormone therapy: Analysis of KIGS (Pfizer International Growth Database)
Extreme degrees of obesity may occur in association with hypothalamic tumors, usually after surgical intervention. This phenomenon has been reported to occur in as many as 25-75% of children undergoing extensive surgical extirpation of craniopharyngiomas (Cranio). Because less is known about the auxology of children with Cranio with milder alterations in growth, we undertook a 3-yr longitudinal an
Nya rön om behandling av djup ventrombos: Behandlingstidens längd föremål för internationella studier
Kinetics and mechanisms in the ammoxidation of toluene over a V2O5 catalyst. Part 1: Selective reactions
A thorough kinetic investigation of the ammoxidation of toluene over a V2O5 catalyst was carried out. Pressures of reactants were varied and rates for formation of benzonitrile and benzaldehyde were determined. Kinetic expressions completely describing experimental data were derived. A mechanisms is proposed on basis of both rate equations and other types of information published in the literature
Non-invasive measurement of arterial longitudinal movement
In arterial vessel wall characterisation the longitudinal movements of vessels have gained little or no attention. It has been presumed that the arterial vessels move very little in the longitudinal direction. With modern high resolution ultrasound it can, however, be seen that arterial vessels move not only in the circumferential, but also in longitudinal direction. This paper describes a non-inv
Gamma-ray Spectroscopy of Core-excited States in 51Mn
The level scheme of Mn-51 has been investigated using the Si-28(S-32 2alpha1p)Mn-51 fusion-evaporation reaction at 125 MeV beam energy. The gamma rays were detected in the Ge-detector array Gammasphere, which was coupled to the 4pi-charged-particle detector Microball and the Neutron Shell for the coincident detection of evaporated particles. Over 100 new gamma-ray transitions connecting some 50 ex
