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The principal function of Saccharomyces cerevisiae Cdc13p is to provide a loading platform to recruit complexes that provide end protection and telomere replication. We isolated the Saccharomyces castellii Cdc13p homolog (scasCdc13p) and characterized the in vitro DNA binding features of the purified recombinant scasCdc13p. The full-length scasCdc13p binds specifically to G-rich single-stranded te
Popular Abstract in Swedish Avhandlingen handlar om hur kvinnlig omskärelse diskuteras av svensksomalier, men också om hur kvinnlig omskärelse diskuteras offentligt i det svenska samhället. Det konstateras att det finns en stor klyfta mellan dessa diskurser. Utifrån en analys av den interna debatten om kvinnlig omskärelse bland somalier i Malmö, hävdas att denna praktik debatteras och omvärderas 'Created by God' presents the views of Swedish Somalis on female circumcision and contrasts it to the Swedish public discourse on the issue. Despite the lack of documented illegal cases of female circumcision in Sweden, it is constantly claimed in the public discourse that female circumcision (female genital mutilation) is a practice upheld by the Somali exile group in Sweden. Based on an analys
Popular Abstract in Swedish Allt fler ungdomar i vårt land, liksom i många andra länder, lever i vardagen med mer än en kultur. En femtedel av eleverna i den svenska skolan är antingen själva födda i ett annat land eller har minst en förälder med utländsk bakgrund. För många av dessa barn och ungdomar har därför inte samhällets dominerande kultur funnits med från början av deras liv. Bekantskapen The present study is based on interviews with 22 youth and young adults. The perspective is phenomenological, since my aim has been to analyse and describe the everyday world as it presents itself to these young people. A process begins in the encounter with the majority culture and the emphasis is on how they think about events and experiences along the road to a more complex life-world. The proc
2,4,6-Trichlorophenol (2,4,6-TCP) was extracted from liquid samples (standards and spiked river water) using immuno-supported liquid membrane (ISLM) extraction followed by fluorescence flow immunoassay (FFIA) detection of the immuno-extracted analyte. ISLM-FFIA involves simultaneous on-line sample clean-up, enrichment and detection of analytes. The analyte is transported from a continuously flowin
The diffractive photoproduction of rho mesons, ep -> e rho Y, with large momentum transfer squared at the proton vertex, vertical bar t vertical bar, is studied with the H1 detector at HERA using an integrated luminosity of 20.1 pb(-1). The photon-proton centre of mass energy spans the range 75 < W < 95 GeV, the photon virtuality is restricted to Q(2) < 0.01 GeV2 and the mass My of the proton remn
The bacterial superantigen, staphylococcal enterotoxin A (SEA) activates T cells with high frequency and directs them to lyse MHC-class-II-expressing cells in superantigen-dependent cell-mediated cytotoxicity (SDCC). Treatment of mice with SEA induced strong CD8+ T-cell(CTL)-mediated SDCC, as well as abundant cytokine production from CD4+ and CD8+ T cells. However, both cytotoxicity and cytokine r
Popular Abstract in Swedish Alla regler system kan betraktas som system med begränsad kapacitet. Detta arbetet består av fyra delar. Den första delen betraktar reglering av låsningsfria bromsar (ABS). Den andra delen betraktar en tuning metod för PID regulatorer. Den tredje delen beskriver servoproblemet för styckvislinjära system samt en anti-windup syntes metod. Den sista delen beskriver ett späVirtually all real life systems are such that they present some kind of limitation on one or many of its variables, physical quantities. These systems are designated in this thesis as systems with limited capacity. This work is treating control related problems of a subclass of such systems, where the limitation is a critical factor. The thesis is composed of four parts. The first part is treatin
The following presentation is primarily intended to stimulate and facilitate a future development towards an improved situation for a reliability based structural fire engineering design of timber structures. The state of the art is reviewed and a structure of a design guide or a model code is outlined. The document is written in a partially operational manner, allowing practical application for s
Background Infant or maternal injury during vaginal delivery is a constant threat to all involved, but difficult to predict. Objective To estimate the risk of birth injuries in an institution favouring trial of vaginal birth when there was doubt of the best mode of delivery. Design A retrospective cohort study. Setting University Hospital. Population Singleton 14,359 vaginal deliveries in ceph
The response of a bacterial community to liming of a forest humus soil (pH 4.9 increased to pH 7.5) was studied in the laboratory at three temperatures (5, 20, and 30degreesC). As a comparison an unlimed soil (pH 4.9) and a soil limed in the field 15 years ago (pH around 6) were also included. The bacterial community tolerance of pH was measured using TdR incorporation. The pH of the bacterial sus
Objective: to evaluate the efficacy of a micromised purified flavonoid fraction (MPFF) in the treatment of chronic venous disease (CVD). Design: prospective doable blind, randomised, control shady. Patients and methods: one hundred and one patients with symptomatic CVD were randomly allocated to treatment for 60 days with either MPFF (51 patients) or placebo (50 patients) 500 mg twice daily. There
This paper presents an analysis of the impact of childbearing history on later-life mortality for ever-married men and women using historical micro-level data of high quality for southern Sweden. The analysis uses a Cox proportional hazards model, estimating the effects on old-age mortality of number of births and timing of first and last births. By studying the effects of previous childbearing on
An image solution for the forced response of a clamped finite beam is developed. The finite beam is replaced by an infinite beam under spatially periodic excitation and periodic support reactions. The response is then found by a Fourier transform approach, making use of the periodicity. An explicit expression is found, using the Poisson sum formula. The aim is to describe the potential of using th
The kinetics and mechanism of the reaction between [PtI3(AsPh3)](-) and pyridine in acetonitrile solvent has been studied by use of stopped-flow spectrophotometry. Substitution of iodide trans to arsine is irreversible under the conditions used and takes place via parallel direct and solvolytic pathways. By comparing the rate constants of the direct pathway with literature values of the correspond
We present an investigation of current cross correlators in mesoscopic conductors. Making an analogy to the optical Hanbury Brown Twiss experiment we discuss how quantum statistical effects and two-particle interference effects can be investigated with current cross correlations. We also discuss how current cross correlations can be used for detecting two-particle entanglement and to perform quant
The conditions for binding of antibodies to glycosphingolipids separated on a thin-layer plate have been optimized for polyclonal antisera. The method has a broad detection range with low background staining. Examples are shown for the detection of blood group A and B active glycosphingolipids.
Previous studies have shown that the functional efficacy of intrastriatal transplants of fetal dopamine (DA) neurons in the rat Parkinson model depends on their ability to establish a new functional innervation of the denervated striatum. Here we report that the survival, growth, and function of the grafted DA neurons greatly depend on the severity of the lesion of the host nigrostriatal system. F
