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Human meconium contains significant amounts of alkaline sphingomyelinase, neutral ceramidase, and sphingolipid metabolites.

Intestinal alkaline sphingomyelinase (Alk-SMase) and neutral ceramidase may catalyze the hydrolysis of endogenous sphin-gomyelin (SM) and milk SM in human-milk fed infants. The enzymes generate sphingolipid metabolites that may influence gut maturation. Alk-SMase also inactivates platelet-activating factor (PAF) that is involved in the pathogenesis of necrotizing enterocolitis (NEC). We examined w

Effects of surface characteristics on infiltration patterns in an arid shrub desert

Precipitation is often the sole source of water replenishment in arid and semi-arid areas and, thus, plays a pertinent role in sustaining desert ecosystems. Revegetation over 40 years using mainly Artemisia ordosica and Caragana korshinskii at Shapotou Desert Experimental Research Station near Lanzhou, China, has established a dwarf-shrub and microbiotic soil crust cover on the stabilized sand dun

CA IX is an independent prognostic marker in premenopausal breast cancer patients with one to three positive lymph nodes and a putative marker of radiation resistance

Purpose: Hypoxia in breast cancer is associated with poor prognosis and down-regulation of the estrogen receptor. Carbonic anhydrase IX (CA IX) is a hypoxia-inducible gene that has been associated with poor outcome in many epithelial cancers. Previous studies of CA IX in breast cancer have been carried out on mixed cohorts of premenopausal and postmenopausal patients with locally advanced disease

Hurlbutite, the first Be mineral from Vastana iron mine, Skane, Sweden

Hurlbutite has been identified as the first Be mineral from the Vastan (a) over circle iron mine, Sk (a) over circle ne, Sweden. The mineral is yellowish to whitish and its microscopic habit is platy and porous. Associated minerals are pinkish apatite, hematite, quartz and svanbergite. The unit cell dimensions calculated from powder X-ray diffraction data are: a = 8.321(8) Angstrom, b = 8.834(8) A

New propranolol analogues: binding and chiral discrimination by cellobiohydrolase Cel7A

Novel propranolol analogues have been designed and synthesised and their enantioselective binding to the cellulose degrading enzyme, Cel7A, has been evaluated. Affinity and enantioselectivity have been determined by capillary electrophoresis experiments. Ligands with significantly improved affinity and selectivity have been obtained and an analysis of the results has led to insights concerning the

Effects of a large-scale introduction of the pneumococcal polysaccharide vaccine among elderly persons in Stockholm, Sweden

In October 1998 Stockholm County launched a 3-year vaccination campaign with the 23-valent pneumococcal polysaccharide vaccine (PPV-23) directed towards all elderly persons. We analysed the impact of this campaign on the incidence and serotype distribution of invasive pneumococcal disease (IPD) in Stockholm County, where the vaccine coverage was 36%, as compared to Skane County, where no vaccinati

Growth of arbuscular mycorrhizal mycelium in calcareous dune sand and its interaction with other soil microorganisms as estimated by measurement of specific fatty acids

Fatty acid analysis was used for determining the extent of the development of the external mycelium of AM fungi (mixed inoculum from a sand dune) growing from roots of Festuca rubra and Plantago lanceolata in calcareous dune sand. The plants were raised in chambers specially designed to permit the growth of AM mycelium in root-free compartments. In two separate experiments, growth of external myce

Toxic potential of five freshwater Phormidium species (Cyanoprokaryota)

Among the Cyanoprokaryota (blue-green algae), the genus Phormidium has thus far rarely been studied with respect to toxin production and potentially resulting human and environmental health effects. We here show that five previously unexplored freshwater species of this genus (Ph. bijugatum, Ph. molle, Ph. papyraceum, Ph. uncinatum, Ph. autumnale) are indeed capable of producing bioactive compound

The complement: A solution to liquid drop finite size effects in phase transitions

The effects of the finite size of a liquid drop undergoing a phase transition are described in terms of the complement, the largest (but mesoscopic) drop representing the liquid in equilibrium with the vapor. Vapor cluster concentrations, pressure, and density from fixed mean density lattice gas (Ising) calculations are explained in terms of the complement generalization of Fisher's model. Account

Boundary conditions in the envelope function approximation as applied to semiconductor heterostructures: The multi-band case

We have found the equations that determine the self-adjoint extensions, and thus the boundary conditions, of the differential operator used in the multi-band k.p-theory, when the coefficients in the Kane-matrix are piecewise constant. Both the one-dimensional and the three-dimensional case have been investigated. A numerical calculation shows that the choice of boundary conditions affects the ener

Socioeconomic differences in fat intake in a middle-aged population: report from the Malmö Diet and Cancer Study

Background: The objective was to investigate whether socioeconomic differences in fat intake may explain socioeconomic differences in cardiovascular diseases. Methods: The Malm Diet and Cancer Study is a prospective cohort study. The baseline examinations used in the present cross-sectional study were undertaken in 19921994. Dietary habits were assessed using a modified diet history method consist

The predissociation of highly excited states in acetylene by time-resolved photoelectron spectroscopy

We study the dynamics of highly excited states in acetylene initiated by an ultrashort vacuum ultraviolet laser pulse. Electronic states lying in the 4s-3d Rydberg region are excited with one femtosecond pulse, and the dynamic development of the states is monitored by a second short pulse which ionizes the system. We show that even for femtosecond pulses where the bandwidth of the exciting pulse c

Effect of fast CO2 pressure changes on the yield of lovage (Levisticum officinale Koch.) and celery (Apium graveolens L.) extracts

The effect of pressure alterations on the yield of CO2, extracts from different anatomical parts of lovage (Levisticum officinale Koch.) and celery (Apium graveolens L.) was studied. It was found that by applying frequent pressure changes in the extraction vessel it is possible to increase the rate of the isolation of CO2 soluble materials from lovage seeds and leaves, lovage and celery roots. How

A Jurassic (Pliensbachian) flora from Bornholm, Denmark - a study of a historic plant-fossil collection at Lund University, Sweden

A historic collection of plant fossils from the Baga Formation, Bornholm, Denmark registered at the Lund University is reviewed and found to be dominated by ferns with subsidiary Ginkgoales, Coniferales, Bennettitales and Equisitales. Ten genera are represented, of which six can be confidently identified to species level. The Baga Formation flora is most similar in age to the flora of the Middle J

C2-Symmetric Macrocyclic Carbohydrate/Amino Acid Hybrids through Copper(I)-Catalyzed Formation of 1,2,3-Triazoles

An efficient method was developed for the preparation of macrocyclic carbohydrate/amino acid hybrids by macrocyclization with copper(I)-catalyzed 1,2,3-triazole formation. Methyl 2-amino-6-azido-3,4-di-O-benzoyl-2,6-dideoxy--D-glucopyranoside was prepared and coupled to two different N-propiolyl dipeptides (propiolyl-Tyr-Tyr-OH and propiolyl-Arg(Mtr)-Tyr-OH) to obtain bifunctional molecules carryi

A traditional agroforestry system under threat: an analysis of the gum arabic market and cultivation in the Sudan

The main aim of this study is to review the environmental and socioeconomic sustainability of the gum arabic farming system in central Sudan. A further aim is to analyse some of the main factors influencing production in recent decades in order to understand the future trade potential and consequently the smallholder livelihood. The study shows that end-user imports of gum arabic have increased du

Role of chromoendoscopy in colon cancer surveillance in inflammatory bowel disease.

Inflammation in the intestine is a well-known risk factor for neoplastic changes in the mucosa. In fact, it has been shown that long-standing ulcerative colitis and colonic Crohn's disease have a significantly increased risk for developing colorectal cancer, although the estimates vary widely between studies. Conventional colonoscopy is effective in detecting polypoid changes in the mucosa. Howeve

Diesel fuel jet lift-off stabilization in the presence of laser-induced plasma ignition

The mechanisms affecting lift-off stabilization at diesel conditions were investigated by laser-igniting a diesel fuel jet upstream of its natural lift-off position. Single-nozzle fuel sprays penetrating into all optically accessible constant-volume chamber were ignited using laser-induced plasma formation both prior to natural autoignition or after a quasi-steady lift-off length was established.